1,539 research outputs found
The 3D Spin Geometry of the Quantum Two-Sphere
We study a three-dimensional differential calculus on the standard Podles
quantum two-sphere S^2_q, coming from the Woronowicz 4D+ differential calculus
on the quantum group SU_q(2). We use a frame bundle approach to give an
explicit description of the space of forms on S^2_q and its associated spin
geometry in terms of a natural spectral triple over S^2_q. We equip this
spectral triple with a real structure for which the commutant property and the
first order condition are satisfied up to infinitesimals of arbitrary order.Comment: v2: 25 pages; minor change
The ADHM Construction of Instantons on Noncommutative Spaces
We present an account of the ADHM construction of instantons on Euclidean
space-time from the point of view of noncommutative geometry. We
recall the main ingredients of the classical construction in a coordinate
algebra format, which we then deform using a cocycle twisting procedure to
obtain a method for constructing families of instantons on noncommutative
space-time, parameterised by solutions to an appropriate set of ADHM equations.
We illustrate the noncommutative construction in two special cases: the
Moyal-Groenewold plane and the Connes-Landi plane
.Comment: Latex, 40 page
Towards a Holistic Migration Research Strategic Agenda: Integration, Partnerships, and Impact
The London International Development Centre Migration Leadership Team (LIDC-MLT) was commissioned by the UK Economic and Social Research Council (ESRC) and the Arts and Humanities Research Council (AHRC), which are part of UK Research and Innovation (UKRI), to develop a shared interdisciplinary and participatory strategic agenda for supporting migration research. This document sets out proposals for ESRC/AHRC and wider UKRI-funded migration research for the next five years (2020-2025) making clear recommendations about future agenda-setting and work prioritie
Phosphorylation of proteins in chick ciliary ganglion under conditions that induce long-lasting changes in synaptic transmission:phosphoprotein targets for nitric oxide action
Correlations Between Variations in Solar EUV and Soft X-Ray Irradiance and Photoelectron Energy Spectra Observed on Mars and Earth
Solar extreme ultraviolet (EUV; 10-120 nm) and soft X-ray (XUV; 0-10 nm) radiation are major heat sources for the Mars thermosphere as well as the primary source of ionization that creates the ionosphere. In investigations of Mars thermospheric chemistry and dynamics, solar irradiance models are used to account for variations in this radiation. Because of limited proxies, irradiance models do a poor job of tracking the significant variations in irradiance intensity in the EUV and XUV ranges over solar rotation time scales when the Mars-Sun-Earth angle is large. Recent results from Earth observations show that variations in photoelectron energy spectra are useful monitors of EUV and XUV irradiance variability. Here we investigate photoelectron energy spectra observed by the Mars Global Surveyor (MGS) Electron Reflectometer (ER) and the FAST satellite during the interval in 2005 when Earth, Mars, and the Sun were aligned. The Earth photoelectron data in selected bands correlate well with calculations based on 1 nm resolution observations above 27 nm supplemented by broadband observations and a solar model in the 0-27 nm range. At Mars, we find that instrumental and orbital limitations to the identifications of photoelectron energy spectra in MGS/ER data preclude their use as a monitor of solar EUV and XUV variability. However, observations with higher temporal and energy resolution obtained at lower altitudes on Mars might allow the separation of the solar wind and ionospheric components of electron energy spectra so that they could be used as reliable monitors of variations in solar EUV and XUV irradiance than the time shifted, Earth-based, F(10.7) index currently used
Cost-Effectiveness of a national initiative to improve hand hygiene compliance using the outcome of healthcare associated staphylococcus aureus bacteraemia
© 2016 Graves et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Background The objective is to estimate the incremental cost-effectiveness of the Australian National Hand Hygiene Inititiave implemented between 2009 and 2012 using healthcare associated Staphylococcus aureus bacteraemia as the outcome. Baseline comparators are the eight existing state and territory hand hygiene programmes. The setting is the Australian public healthcare system and 1,294,656 admissions from the 50 largest Australian hospitals are included. Methods The design is a cost-effectiveness modelling study using a before and after quasi-experimental design. The primary outcome is cost per life year saved from reduced cases of healthcare associated Staphylococcus aureus bacteraemia, with cost estimated by the annual on-going maintenance costs less the costs saved from fewer infections. Data were harvested from existing sources or were collected prospectively and the time horizon for the model was 12 months, 2011-2012. Findings No useable pre-implementation Staphylococcus aureus bacteraemia data were made available from the 11 study hospitals in Victoria or the single hospital in Northern Territory leaving 38 hospitals among six states and territories available for cost-effectiveness analyses. Total annual costs increased by 29,700 per life year gained. Probabilistic sensitivity analysis revealed a 100% chance the initiative was cost effective in the AustralianCapital Territory and Queensland, with ICERs of 8,988 respectively. There was an 81% chance it was cost effective in New South Wales with an ICER of 64,729 and a 1% chance for Tasmania and Western Australia. The 12 hospitals in Victoria and the Northern Territory incur annual on-going maintenance costs of 42,000 per life year gained. The return on investment varied among the states and territories of Australia
Recognition of cancer warning signs and anticipated time to help-seeking in a population sample of adults in the UK
Background: Not recognising a symptom as suspicious is a common reason given by cancer patients for delayed help-seeking; but inevitably this is retrospective. We therefore investigated associations between recognition of warning signs for breast, colorectal and lung cancer and anticipated time to help-seeking for symptoms of each cancer.
Methods: Computer-assisted telephone interviews were conducted with a population-representative sample (N=6965) of UK adults age greater than or equal to50 years, using the Awareness and Beliefs about Cancer scale. Anticipated time to help-seeking for persistent cough, rectal bleeding and breast changes was categorised as >2 vs less than or equal to2 weeks. Recognition of persistent cough, unexplained bleeding and unexplained lump as cancer warning signs was assessed (yes/no). Associations between recognition and help-seeking were examined for each symptom controlling for demographics and perceived ease of health-care access.
Results: For each symptom, the odds of waiting for >2 weeks were significantly increased in those who did not recognise the related warning sign: breast changes: OR=2.45, 95% CI 1.47–4.08; rectal bleeding: OR=1.77, 1.36–2.30; persistent cough: OR=1.30, 1.17–1.46, independent of demographics and health-care access.
Conclusion: Recognition of warning signs was associated with anticipating faster help-seeking for potential symptoms of cancer. Strategies to improve recognition are likely to facilitate earlier diagnosis
Finitely-Generated Projective Modules over the Theta-deformed 4-sphere
We investigate the "theta-deformed spheres" C(S^{3}_{theta}) and
C(S^{4}_{theta}), where theta is any real number. We show that all
finitely-generated projective modules over C(S^{3}_{theta}) are free, and that
C(S^{4}_{theta}) has the cancellation property. We classify and construct all
finitely-generated projective modules over C(S^{4}_{\theta}) up to isomorphism.
An interesting feature is that if theta is irrational then there are nontrivial
"rank-1" modules over C(S^{4}_{\theta}). In that case, every finitely-generated
projective module over C(S^{4}_{\theta}) is a sum of a rank-1 module and a free
module. If theta is rational, the situation mirrors that for the commutative
case theta=0.Comment: 34 page
Mammographic screening for young women with a family history of breast cancer: knowledge and views of those at risk
Although the effectiveness of mammography for women under the age of 50 years with a family history of breast cancer (FHBC) has not yet been proven, annual screening is being offered to these women to manage breast cancer risk. This study investigates women's awareness and interpretation of their familial risk and knowledge and views about mammographic screening. A total of 2231 women from 21 familial/breast/genetics centres who were assessed as moderate risk (17–30% lifetime risk) or high risk (>30% lifetime risk) completed a questionnaire before their mammographic screening appointment. Most women (70%) believed they were likely, very likely or definitely going to develop breast cancer in their lifetime. Almost all women (97%) understood that the purpose of mammographic screening was to allow the early detection of breast cancer. However, 20% believed that a normal mammogram result meant there was definitely no breast cancer present, and only 4% understood that screening has not been proven to save lives in women under the age of 50 years. Women held positive views on mammography but did not appear to be well informed about the potential disadvantages. These findings suggest that further attention should be paid to improving information provision to women with an FHBC being offered routine screening
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