3,055 research outputs found

    On the role of information in strategic and individual decision making

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    This dissertation comprises four independent chapters, each exploring the impact of information on decision-making processes within economic contexts. The overarching theme across these chapters is the role of information in shaping human behaviour and economic outcomes. The first two chapters investigate strategic interactions involving a sender possessing information desired by a receiver. The first chapter employs game theory to analyse these interactions, while the second chapter adopts an experimental approach to delve into how habits affect strategic communication. The third chapter investigates the influence of irrelevant information on individuals' valuation of goods, exploring whether market interactions mitigate this effect. The fourth chapter studies the decision-making process surrounding the disclosure of information pertaining to corporate fraud through whistleblowing mechanisms. Through these diverse topics, this dissertation contributes to the broader understanding of how information intersects with economic decision-making processes

    Anchoring on valuations and perceived informativeness

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    Anchoring is a cognitive bias whereby individuals’ decisions are influenced by an uninformative number, the anchor. Anchoring bias for valuations of goods has important implications for consumer decisions, but its’ robustness has been questioned by recent studies. We investigate the effect of the perceived informativeness of the anchor on valuations of goods. In an online experiment, we vary the amount of information about the process by which the anchor was determined, and hypothesise that the more information provided, the less scope is left for the anchor to be perceived as non-random/informative, thus mitigating anchoring effects. Our results provide evidence that the perceived informativeness of the anchor does affect anchoring effects. Contrary to our prediction, we find stronger anchoring effects when more information is presented.</p

    On the role of information in strategic and individual decision making

    Get PDF
    This dissertation comprises four independent chapters, each exploring the impact of information on decision-making processes within economic contexts. The overarching theme across these chapters is the role of information in shaping human behaviour and economic outcomes. The first two chapters investigate strategic interactions involving a sender possessing information desired by a receiver. The first chapter employs game theory to analyse these interactions, while the second chapter adopts an experimental approach to delve into how habits affect strategic communication. The third chapter investigates the influence of irrelevant information on individuals' valuation of goods, exploring whether market interactions mitigate this effect. The fourth chapter studies the decision-making process surrounding the disclosure of information pertaining to corporate fraud through whistleblowing mechanisms. Through these diverse topics, this dissertation contributes to the broader understanding of how information intersects with economic decision-making processes

    xPF: Packet Filtering for Low-Cost Network Monitoring

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    The ever-increasing complexity in network infrastructures is making critical the demand for network monitoring tools. While the majority of network operators rely on low-cost open-source tools based on commodity hardware and operating systems, the increasing link speeds and complexity of network monitoring applications have revealed inefficiencies in the existing software organization, which may prohibit the use of such tools in high-speed networks. Although several new architectures have been proposed to address these problems, they require significant effort in re-engineering the existing body of applications. We present an alternative approach that addresses the primary sources of inefficiency without significantly altering the software structure. Specifically, we enhance the computational model of the Berkeley packet filter (BPF) to move much of the processing associated with monitoring into the kernel, thereby removing the overhead associated with context switching between kernel and applications. The resulting packet filter, called xPF, allows new tools to be more efficiently implemented and existing tools to be easily optimized for high-speed networks. We present the design and implementation of xPF as well as several example applications that demonstrate the efficiency of our approach

    Selection in Reported Epidemiological Risks: An Empirical Assessment

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    BACKGROUND: Epidemiological studies may be subject to selective reporting, but empirical evidence thereof is limited. We empirically evaluated the extent of selection of significant results and large effect sizes in a large sample of recent articles. METHODS AND FINDINGS: We evaluated 389 articles of epidemiological studies that reported, in their respective abstracts, at least one relative risk for a continuous risk factor in contrasts based on median, tertile, quartile, or quintile categorizations. We examined the proportion and correlates of reporting statistically significant and nonsignificant results in the abstract and whether the magnitude of the relative risks presented (coined to be consistently ≥1.00) differs depending on the type of contrast used for the risk factor. In 342 articles (87.9%), ≥1 statistically significant relative risk was reported in the abstract, while only 169 articles (43.4%) reported ≥1 statistically nonsignificant relative risk in the abstract. Reporting of statistically significant results was more common with structured abstracts, and was less common in US-based studies and in cancer outcomes. Among 50 randomly selected articles in which the full text was examined, a median of nine (interquartile range 5–16) statistically significant and six (interquartile range 3–16) statistically nonsignificant relative risks were presented (p = 0.25). Paradoxically, the smallest presented relative risks were based on the contrasts of extreme quintiles; on average, the relative risk magnitude was 1.41-, 1.42-, and 1.36-fold larger in contrasts of extreme quartiles, extreme tertiles, and above-versus-below median values, respectively (p < 0.001). CONCLUSIONS: Published epidemiological investigations almost universally highlight significant associations between risk factors and outcomes. For continuous risk factors, investigators selectively present contrasts between more extreme groups, when relative risks are inherently lower

    Local Literature Bias in Genetic Epidemiology: An Empirical Evaluation of the Chinese Literature

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    BACKGROUND: Postulated epidemiological associations are subject to several biases. We evaluated whether the Chinese literature on human genome epidemiology may offer insights on the operation of selective reporting and language biases. METHODS AND FINDINGS: We targeted 13 gene-disease associations, each already assessed by meta-analyses, including at least 15 non-Chinese studies. We searched the Chinese Journal Full-Text Database for additional Chinese studies on the same topics. We identified 161 Chinese studies on 12 of these gene-disease associations; only 20 were PubMed-indexed (seven English full-text). Many studies (14–35 per topic) were available for six topics, covering diseases common in China. With one exception, the first Chinese study appeared with a time lag (2–21 y) after the first non-Chinese study on the topic. Chinese studies showed significantly more prominent genetic effects than non-Chinese studies, and 48% were statistically significant per se, despite their smaller sample size (median sample size 146 versus 268, p < 0.001). The largest genetic effects were often seen in PubMed-indexed Chinese studies (65% statistically significant per se). Non-Chinese studies of Asian-descent populations (27% significant per se) also tended to show somewhat more prominent genetic effects than studies of non-Asian descent (17% significant per se). CONCLUSION: Our data provide evidence for the interplay of selective reporting and language biases in human genome epidemiology. These biases may not be limited to the Chinese literature and point to the need for a global, transparent, comprehensive outlook in molecular population genetics and epidemiologic studies in general

    Investigating the value of radiomics stemming from DSC quantitative biomarkers in IDH mutation prediction in gliomas

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    Objective: This study aims to assess the value of biomarker based radiomics to predict IDH mutation in gliomas. The patient cohort consists of 160 patients histopathologicaly proven of primary glioma (WHO grades 2–4) from 3 different centers. Methods: To quantify the DSC perfusion signal two different mathematical modeling methods were used (Gamma fitting, leakage correction algorithms) considering the assumptions about the compartments contributing in the blood flow between the extra- and intra vascular space. Results: The Mean slope of increase (MSI) and the K1 parameter of the bidirectional exchange model exhibited the highest performance with (ACC 74.3% AUROC 74.2%) and (ACC 75% AUROC 70.5%) respectively. Conclusion: The proposed framework on DSC-MRI radiogenomics in gliomas has the potential of becoming a reliable diagnostic support tool exploiting the mathematical modeling of the DSC signal to characterize IDH mutation status through a more reproducible and standardized signal analysis scheme for facilitating clinical translation
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