447 research outputs found
Social Support and the Perception of Geographical Slant.
The visual perception of geographical slant is influenced by physiological resources, such as physical fitness, age, and being physically refreshed. In two studies we tested whether a psychosocial resource, social support, can also affect the visual perception of slants. Participants accompanied by a friend estimated a hill to be less steep when compared to participants who were alone (Study 1). Similarly, participants who thought of a supportive friend during an imagery task saw a hill as less steep than participants who either thought of a neutral person or a disliked person (Study 2). In both studies, the effects of social relationships on visual perception appear to be mediated by relationship quality (i.e., relationship duration, interpersonal closeness, warmth). Artifacts such as mood, social desirability, and social facilitation did not account for these effects. This research demonstrates that an interpersonal phenomenon, social support, can influence visual perception
Schooling for violence and peace : how does peace education differ from ânormalâ schooling?
This article reviews literature on the roles of schooling in both reproducing and actively perpetrating violence, and sets out an historical explanation of why schools are socially constructed in such a way as to make these roles possible. It then discusses notions of peace education in relation to one particular project in England before using empirical data from research on the project to examine contrasts between peace education approaches and ânormalâ schooling from the viewpoints of project workers, pupils and teachers. It concludes that such contrasts and tensions do indeed exist and that this raises serious questions about the compatibility of peace education and formal schooling
Reference Standards for Body Fat Measure Using GE Dual Energy X-Ray Absorptiometry in Caucasian Adults
Background Dual energy x-ray absorptiometry (DXA) is an established technique for the measurement of body composition. Reference values for these variables, particularly those related to fat mass, are necessary for interpretation and accurate classification of those at risk for obesityrelated health complications and in need of lifestyle modifications (diet, physical activity, etc.). Currently, there are no reference values available for GE-Healthcare DXA systems and it is known that whole-body and regional fat mass measures differ by DXA manufacturer.
Objective To develop reference values by age and sex for DXA-derived fat mass measurements with GE-Healthcare systems.
Methods A de-identified sample of 3,327 participants (2,076 women, 1,251 men) was obtained from Ball State University\u27s Clinical Exercise Physiology Laboratory and University of Wisconsin- Milwaukee\u27s Physical Activity & Health Research Laboratory. All scans were completed using a GE Lunar Prodigy or iDXA and data reported included percent body fat (%BF), fat mass index (FMI), and ratios of android-to-gynoid (A/G), trunk/limb, and trunk/leg fat measurements. Percentiles were calculated and a factorial ANOVA was used to determine differences in the mean values for each variable between age and sex.
Results Normative reference values for fat mass variables from DXA measurements obtained from GE-Healthcare DXA systems are presented as percentiles for both women and men in 10- year age groups. Women had higher (p\u3c0.01) mean %BF and FMI than men, whereas men had higher (p\u3c0.01) mean ratios of A/G, trunk/limb, and trunk/leg fat measurements than women
Social support and the perception of geographical slant
The visual perception of geographical slant is influenced by physiological resources, such as physical fitness, age, and being physically refreshed. In two studies we tested whether a psychosocial resource, social support, can also affect the visual perception of slants. Participants accompanied by a friend estimated a hill to be less steep when compared to participants who were alone (Study 1). Similarly, participants who thought of a supportive friend during an imagery task saw a hill as less steep than participants who either thought of a neutral person or a disliked person (Study 2). In both studies, the effects of social relationships on visual perception appear to be mediated by relationship quality (i.e., relationship duration, interpersonal closeness, warmth). Artifacts such as mood, social desirability, and social facilitation did not account for these effects. This research demonstrates that an interpersonal phenomenon, social support, can influence visual perception
Normal-superfluid interaction dynamics in a spinor Bose gas
Coherent behavior of spinor Bose-Einstein condensates is studied in the
presence of a significant uncondensed (normal) component. Normal-superfluid
exchange scattering leads to a near-perfect local alignment between the spin
fields of the two components. Through this spin locking, spin-domain formation
in the condensate is vastly accelerated as the spin populations in the
condensate are entrained by large-amplitude spin waves in the normal component.
We present data evincing the normal-superfluid spin dynamics in this regime of
complicated interdependent behavior.Comment: 5 pages, 4 fig
Urinary ATP and visualization of intracellular bacteria: a superior diagnostic marker for recurrent UTI in renal transplant recipients?
Renal transplant recipients (RTR) are highly susceptible to urinary tract infections (UTIs) with over 50% of patients having at least one UTI within the first year. Yet it is generally acknowledged that there is considerable insensitivity and inaccuracy in routine urinalysis when screening for UTIs. Thus a large number of transplant patients with genuine urine infections may go undiagnosed and develop chronic recalcitrant infections, which can be associated with graft loss and morbidity. Given a recent study demonstrating ATP is released by urothelial cells in response to bacteria exposure, possibly acting at metabotropic P2Y receptors mediating a proinflammatory response, we have investigated alternative, and possibly more appropriate, urinalysis techniques in a cohort of RTRs.Mid-stream urine (MSU) samples were collected from 53 outpatient RTRs. Conventional leukocyte esterase and nitrite dipstick tests, and microscopic pyuria counts (in 1 ?l), ATP concentration measurements, and identification of intracellular bacteria in shed urothelial cells, were performed on fresh unspun samples and compared to âgold-standardâ bacterial culture results.Of the 53 RTRs, 22% were deemed to have a UTI by âgold-standardâ conventional bacteria culture, whereas 87%, 8% and 4% showed evidence of UTIs according to leukocyte esterase dipstick, nitrite dipstick, and a combination of both dipsticks, respectively. Intracellular bacteria were visualized in shed urothelial cells of 44% of RTRs, however only 1 of the 23 RTRs (44%) was deemed to have a UTI by conventional bacteria culture. A significant association of the âgold-standardâ test with urinary ATP concentration combined with visualization of intracellular bacteria in shed urothelial cells was determined using the Fisherâs exact test.It is apparent that standard bedside tests for UTIs give variable results and that seemingly quiescent bacteria in urothelial cells are very common in RTRs and may represent a focus of subclinical infection. Furthermore, our results suggest urinary ATP concentration combined with detection of intracellular bacteria in shed urinary epithelial cells may be a sensitive means by which to detect âoccultâ infection in RTRs
A trapped-ion local field probe
We introduce a measurement scheme that utilizes a single ion as a local field
probe. The ion is confined in a segmented Paul trap and shuttled around to
reach different probing sites. By the use of a single atom probe, it becomes
possible characterizing fields with spatial resolution of a few nm within an
extensive region of millimeters. We demonstrate the scheme by accurately
investigating the electric fields providing the confinement for the ion. For
this we present all theoretical and practical methods necessary to generate
these potentials. We find sub-percent agreement between measured and calculated
electric field values
Defining the Dose of Altitude Training: How High to Live for Optimal Sea Level Performance Enhancement
Defining the dose of altitude training: how high to live for optimal sea level performance enhancement. J Appl Physiol 116: 595-603, 2014. First published October 24, 2013; doi:10.1152/japplphysiol.00634.2013.-Chronic living at altitudes of 2,500 m causes consistent hematological acclimatization in most, but not all, groups of athletes; however, responses of erythropoietin (EPO) and red cell mass to a given altitude show substantial individual variability. We hypothesized that athletes living at higher altitudes would experience greater improvements in sea level performance, secondary to greater hematological acclimatization, compared with athletes living at lower altitudes. After 4 wk of group sea level training and testing, 48 collegiate distance runners (32 men, 16 women) were randomly assigned to one of four living altitudes (1,780, 2,085, 2,454, or 2,800 m). All athletes trained together daily at a common altitude from 1,250-3,000 m following a modified live high-train low model. Subjects completed hematological, metabolic, and performance measures at sea level, before and after altitude training; EPO was assessed at various time points while at altitude. On return from altitude, 3,000-m time trial performance was significantly improved in groups living at the middle two altitudes (2,085 and 2,454 m), but not in groups living at 1,780 and 2,800 m. EPO was significantly higher in all groups at 24 and 48 h, but returned to sea level baseline after 72 h in the 1,780-m group. Erythrocyte volume was significantly higher within all groups after return from altitude and was not different between groups. These data suggest that, when completing a 4-wk altitude camp following the live high-train low model, there is a target altitude between 2,000 and 2,500 m that produces an optimal acclimatization response for sea level performance
Observation of anomalous spin-state segregation in a trapped ultra-cold vapor
We observe counter-intuitive spin segregation in an inhomogeneous sample of
ultra-cold, non-condensed Rubidium atoms in a magnetic trap. We use spatially
selective microwave spectroscopy to verify a model that accounts for the
differential forces on two internal spin states. In any simple understanding of
the cloud dynamics, the forces are far too small to account for the dramatic
transient spin polarizations observed. The underlying mechanism remains to be
elucidated.Comment: 5 pages, 3 figure
Persistent low-level variants in a subset of viral genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infection
ABSTRACT
Background
Human cytomegalovirus is the most common and serious opportunistic infection after solid organ and haematopoietic stem cell transplantation. In this study, we used whole-genome cytomegalovirus data to investigate viral factors associated with the clinical outcome.
Methods
We sequenced cytomegalovirus samples from 16 immunocompromised paediatric patients with persistent viraemia. 8/16 patients died of complications due to cytomegalovirus infection. We also sequenced samples from 35 infected solid organ adult recipients of whom one died with cytomegalovirus infection.
Results
We showed that samples from both groups have fixed variants at resistance sites and mixed infections. NGS sequencing also revealed non-fixed variants at resistance sites in most of the patients who died (6/9). A machine learning approach identified 10 genes with non-fixed variants in these patients. These genes formed a viral signature which discriminated patients with cytomegalovirus infection who died from those that survived with high accuracy (AUC=0.96). Lymphocyte numbers for a subset of patients showed no recovery post-transplant in the patients who died.
Conclusions
We hypothesise that the viral signature identified in this study may be a useful biomarker for poor response to antiviral drug treatment and indirectly for poor T cell function, potentially identifying early, those patients requiring non-pharmacological interventions
- âŠ