Analisa Dan Perbandingan PC Cloning Menggunakan Software Softxpand Dengan Software Aster V7

Personal Computer (PC) Cloning merupakan suatu konsep jaringan komputer yang menekankan pada proses komputasi di sisi server dan sisi client yang berkinerja seminimal mungkin. Software PC Cloning tersedia dalam beberapa versi, antara lain Softxpand dan Aster V7. Analisa ini bertujuan agar mengetahui software yang lebih mumpuni dalam kinerjanya sebagai PC Cloning sehingga komputer server dapat bekerja secara optimal. Metodologi penelitian “Analisa dan Perbandingan Pc cloning menggunakan software softxpand dengan software Aster v7" ini melalui beberapa proses, hal ini bertujuan agar hasil dapat maksimal. Tahapan yang dimulai dengan analisa kebutuhan, pengumpulan perlengkapan, uji coba aplikasi, pengumpulan data, percobaan analisa, hasil analisa sampai dengan tahapan paling akhir adalah pembuatan laporan. Hasil yang telah dicapai dari penelitian tentang analisa dan perbandingan pc cloning menggunakan software softxpand dengan software aster v7. Dengan membandingkan beberapa parameter seperti setting konfigurasi, pemakaian memori, kinerja software saat aplikasi dijalankan secara bersamaan. Dan kinerja software saat implementasi adalah untuk menentukan software yang mumpuni dalam penggunaannya sebagai PC Cloning. Hasil yang didapat yaitu software Softxpand lebih unggul dari pada software Aster V7

New Fractional Spline Polynomial for Computing Fractional Differential Equations

هذا البحث يوضح كيفية تركيب لاكونري كسري لمتعددة حدود من الدرجة الرابعة بأستخدام دالة سبلاين. من ناحية أخرى, تمت مناقشة و اثبات الوحدوية و حدود الخطأ لهذه الدوال. الهدف من هذه الطريقة هو حل المعادلات التفاضلية الكسرية. تم توضيح كفاءة وملاءمة هذه الطرق الجديدة من خلال اعطاء أمثلة حسابية عددية This paper illustrates how fractional lacunary for quartic polynomial using spline function has been constructed.  On the other hand the existence, the uniqueness and error bounded for these functions have been discussed and proved. The goal of this method is to solve fractional differential equations. The efficiency and pertinence of these new methods are illustrated by giving numerically computing examples

Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers

Background: DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a serine threonine kinase belonging to the PIKK family (phosphoinositide 3-kinase-like-family of protein kinase), is a critical component of the non-homologous end joining (NHEJ) pathway required for the repair of DNA double strand breaks. DNA-PKcs may be involved in breast cancer pathogenesis. Methods: We evaluated clinicopathological significance of DNA-PKcs protein expression in 1161 tumours and DNA-PKcs mRNA expression in 1950 tumours. We correlated DNA-PKcs to other markers of aggressive phenotypes, DNA repair, apoptosis and cell cycle regulation. Results: Low DNA-PKcs protein expression was associated with higher tumour grade, higher mitotic index, tumour de-differentiation and tumour type (ps<0.05). Absence of BRCA1, low XRCC1/SMUG1/APE1/Polβ were also more likely in low DNA-PKcs expressing tumours (ps<0.05). Low DNA-PKcs protein expression was significantly associated with worse breast cancer specific survival (BCCS) in univariate and multivariate analysis (ps<0.01). At the mRNA level, low DNA-PKcs was associated with PAM50.Her2 and PAM50.LumA molecular phenotypes (ps<0.01) and poor BCSS. In patients with ER positive tumours who received endocrine therapy, low DNA-PKcs (protein and mRNA) was associated with poor survival. In ER negative patients, low DNA-PKcs mRNA remains significantly associated with adverse outcome. Conclusions: Our study suggests that low DNA-PKcs expression may have prognostic and predictive significance in breast cancers

INTERPOLICY DYNAMICS BETWEEN NONFORMAL EDUCATION POLICY AND LANGUAGE POLICY OF INTERNATIONALISATION THROUGH ILFS TEACHING IN INDONESIA

Republic of Indonesia’s Act Number 24 Year 2009 has mandated among other: (1) the obligation for overseas employees and workers to be proficient in Indonesian language, otherwise they need to be trained in Indonesian language classes; (2) the establishment of a language national agency which must be directly responsible to the minister; and (3) the increasing of Indonesian as the state language function to be an international language. Furthermore, the Government Regulation Number 57 Year 2014 emphasises the policy of Indonesian language internationalisation and it is stated that the policy is undertaken through Bahasa Indonesia bagi Penutur Asing (BIPA) or Indonesian Language for Foreign Speakers (ILFS) teaching program. Within the ILFS field itself, there are three major teaching providers which are: (1) universities, (2) agreement of cooperation schools, and (3) nonformal course and training institutions. This article is a policy analysis report which intends to expose the interpolicy dynamics existing in two education policies implementation; the internationalisation of Indonesian state language policy and the nonformal education policy. The research which is done qualitatively finds that there is an interpolicy synergy or a two-ways-support between the two policies in their implementation process. This is possible due to a good will for intersectoral cooperation and coordination among policy actors; two main governmental leading sectors of the Indonesian Ministry of Education and Culture (MEC), which are (1) the Directorate of Nonformal Courses and Trainings Nurturance (CTN) and (2) the Agency of Language Development and Nurturance (Language Agency), and some nongovernmental ILFS stakeholders, such as the ILFS professional association “APPBIPA”, and the nonformal course and training providers (CTP) themselves. The combination of these organisations has become a unique education policy network in Indonesia.  Article visualizations

Rethinking Museum Space: Interaction Between Spatial Layout Design and Digital Sensory Environments

Over the past decade, there has been a growing awareness of architectural and spatial design in the functioning of museums and the creation of distinctive visitor experiences. This issue has itself become more complex as digital technologies offer new potentials to mediate between museum content and visitors, and in particular technologies which have the capacity to amplify senses and facilitate interactive, whole body, immersive and sensorial experience. The paper will explore for the first time the role of spatial layout in the sensory environments created through digital media in museums. Among the key questions raised are: how are they integrated into the museum itinerary spatially and conceptually? In what kind of spaces are they installed and how do they relate to them? Are they arranged so as to exploit key spatial properties? We investigate these questions initially through the identification and review of existing experimental projects, and then through the in-depth study of examples of the museum work of two well-established creative studios which combine architecture and interaction: Jason Bruges Studio and United Visual Artists. The analysis is based, on the one hand, on interviews with the designers involved in their creation and, on the other, on syntactic concepts and techniques. By looking in parallel at the work of the two studios, from their first installations until now, and through syntactic analysis, we unravel the way these projects become integrated in the museum, both in literal terms (spatial positioning) and in metaphorical (curatorial practice). The analysis shows that as these works become with time more symbolic, they also become less intrinsically spatial and their experience less dependent on movement. More interestingly, it brings to surface aspects of the design of digital sensory environments which have a relation of correspondence with syntactic properties, such as integration, and types of space. Having shown that space plays a key but variable role, the paper ends by proposing a model for the spatial understanding of these novel technology-mediated experiences and for rethinking museum space

CpG Methylation of a Silent Controlling Element in the Murine Avy Allele Is Incomplete and Unresponsive to Methyl Donor Supplementation

Background: The viable yellow allele of agouti (A vy) is remarkable for its unstable and partially heritable epigenetic state, which produces wide variation in phenotypes of isogenic mice. In the A vy allele an inserted intracisternal A particle (IAP) acts as a controlling element which deregulates expression of agouti by transcription from the LTR of the IAP; the phenotypic state has been linked to CpG methylation of the LTR. Phenotypic variation between A vy mice indicates that the epigenetic state of the IAP is unstable in the germline. Principal Findings: We have made a detailed examination of somatic methylation of the IAP using bisulphite allelic sequencing, and find that the promoter is incompletely methylated even when it is transcriptionally silent. In utero exposure to supplementary methyl donors, which alters the spectrum of A vy phenotypes, does not increase the density of CpG methylation in the silent LTR. Conclusions: Our findings suggest that, contrary to previous supposition, methyl donor supplementation acts through an indirect mechanism to silence A vy. The incomplete cytosine methylation we observe at the somatically silent A vy allele ma