Opportunities and Challenges of Youths in a Globalized India

This study centers around the impact of Globalization on the new generation. Globalization is a procedure of collaboration and coordination among individuals, organizations, governments, around the world. Economically, globalization includes mechanization, administrations, financial assets, capital, innovation, and information. Globalization is a progression of ground-breaking forms that give the both chances and dangers. The procedure of globalization for the most part depicts the adjustments in the general society or country, however once in a while tended to the effect of globalization on youth’s points of view. The general outcome indicated that globalization advances a brilliant future for the more youthful age. Youth’s measurements positively affect development in this way; globalization is a key driver of the uncommon highlights for young people and an outcome we presently live in a world with much high poverty, joblessness, and different impediments that are impacted by young people. With this, we can say globalization may have negative outcomes, and yet the greater extent, it presents positive outcomes to the young people of the new generation

Socio-Economics Status of an Irrigation Scheme's Beneficiaries with Non-Beneficiaries: A Comparative Study in Karnataka

India is predominantly an agriculture based country. Agriculture is the source of livelihood security for majority of the rural population. Among 30 states of India, Karnataka is a major state which contributes 8.2 percent in the financial year 2010-2011 and witnessed several transformations with implementations of schemes and programmes during the period of 1970-90. Ganga Kalyana Scheme is a programme which was implemented to uplift SC/STs communities by giving subsidised bore well facilities. So the study intended to compare the socio-economic status of beneficiaries with non-beneficiaries of GKS in Karnataka. The study framed multi-stage simple random sampling design to decide the sampling and collected information directly from the beneficiaries and non-beneficiaries by using proper questionnaire schedule with personal interview and analysed the data with Chi-square, t-test and Extension exposure scores. Finally, this programme has induced our benefitted farmers to have a better socio-economic condition compared to non-benefitted farmers of Ganga Kalyana Scheme

A Study on the Relationship between the Ground Water Resources and the Sustainability of Agricultural and Non-Agricultural Aspects

Human wellbeing and environmental sustainability are the key factors for economic development, which are directly dependent on the water source. Water resources of the state continue to play a crucial role in the sustainable development of the states in the years to come. Groundwater is another vital source for meeting nearly half of the demand for irrigation, industrial production, and municipal water needs for both rural and urban areas. Underdeveloped countries depend on the primary sector more for their livelihood, and groundwater resource is the primary source for their agronomic practices. Because 1/3rd of the agricultural land depends on rainfall in India, the others have been cultivated with surface water and groundwater resources. The surface water source will not be available longer than groundwater. Farmers depend more on groundwater. Due to large output and productivity nowadays, farmers have been digging more bore wells in the land than required and, at the same time-consuming, more power to lift water. These scenarios destroy the agricultural lands' quality of soil by over lifting the water, and there might be land sliding, groundwater exploitation, loss of fossil water, etc. Agricultural dependency has been declining for several reasons, and if agriculture continues the exploitation scenario, what are the severe problems for the future generation? Therefore, the study aims to analyze the influence of the exploitation of groundwater resources through digging bore wells on the sustainability of agricultural lands. The study planned to consider the primary and secondary data using descriptive research analysis

N-[4-Cyano-3-(trifluoro­meth­yl)phen­yl]-2-meth­oxy­benzamide

In the title compound, C16H11F3N2O2, the carboxamide group connecting the two aromatic rings is in a syn-periplanar configuration; the mol­ecule is non-planar; the dihedral angle between the two aromatic rings is 13.95 (18)°. Intra­molecular N—H⋯O and C—H⋯O hydrogen bonds occur. In the crystal, mol­ecules are linked by inter­molecular C—H⋯O hydrogen bonds

Clinical trials for stem cell therapies

In recent years, clinical trials with stem cells have taken the emerging field in many new directions. While numerous teams continue to refine and expand the role of bone marrow and cord blood stem cells for their vanguard uses in blood and immune disorders, many others are looking to expand the uses of the various types of stem cells found in bone marrow and cord blood, in particular mesenchymal stem cells, to uses beyond those that could be corrected by replacing cells in their own lineage. Early results from these trials have produced mixed results often showing minor or transitory improvements that may be attributed to extracellular factors. More research teams are accelerating the use of other types of adult stem cells, in particular neural stem cells for diseases where beneficial outcome could result from either in-lineage cell replacement or extracellular factors. At the same time, the first three trials using cells derived from pluripotent cells have begun

Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method.

Coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented pressure on healthcare system globally. Lack of high-quality evidence on the respiratory management of COVID-19-related acute respiratory failure (C-ARF) has resulted in wide variation in clinical practice. Using a Delphi process, an international panel of 39 experts developed clinical practice statements on the respiratory management of C-ARF in areas where evidence is absent or limited. Agreement was defined as achieved when > 70% experts voted for a given option on the Likert scale statement or > 80% voted for a particular option in multiple-choice questions. Stability was assessed between the two concluding rounds for each statement, using the non-parametric Chi-square (χ <sup>2</sup> ) test (p < 0·05 was considered as unstable). Agreement was achieved for 27 (73%) management strategies which were then used to develop expert clinical practice statements. Experts agreed that COVID-19-related acute respiratory distress syndrome (ARDS) is clinically similar to other forms of ARDS. The Delphi process yielded strong suggestions for use of systemic corticosteroids for critical COVID-19; awake self-proning to improve oxygenation and high flow nasal oxygen to potentially reduce tracheal intubation; non-invasive ventilation for patients with mixed hypoxemic-hypercapnic respiratory failure; tracheal intubation for poor mentation, hemodynamic instability or severe hypoxemia; closed suction systems; lung protective ventilation; prone ventilation (for 16-24 h per day) to improve oxygenation; neuromuscular blocking agents for patient-ventilator dyssynchrony; avoiding delay in extubation for the risk of reintubation; and similar timing of tracheostomy as in non-COVID-19 patients. There was no agreement on positive end expiratory pressure titration or the choice of personal protective equipment. Using a Delphi method, an agreement among experts was reached for 27 statements from which 20 expert clinical practice statements were derived on the respiratory management of C-ARF, addressing important decisions for patient management in areas where evidence is either absent or limited. The study was registered with Clinical trials.gov Identifier: NCT04534569

Human platelet lysate as a fetal bovine serum substitute improves human adipose-derived stromal cell culture for future cardiac repair applications

Adipose-derived stromal cells (ASC) are promising candidates for cell therapy, for example to treat myocardial infarction. Commonly, fetal bovine serum (FBS) is used in ASC culturing. However, FBS has several disadvantages. Its effects differ between batches and, when applied clinically, transmission of pathogens and antibody development against FBS are possible. In this study, we investigated whether FBS can be substituted by human platelet lysate (PL) in ASC culture, without affecting functional capacities particularly important for cardiac repair application of ASC. We found that PL-cultured ASC had a significant 3-fold increased proliferation rate and a significantly higher attachment to tissue culture plastic as well as to endothelial cells compared with FBS-cultured ASC. PL-cultured ASC remained a significant 25% smaller than FBS-cultured ASC. Both showed a comparable surface marker profile, with the exception of significantly higher levels of CD73, CD90, and CD166 on PL-cultured ASC. PL-cultured ASC showed a significantly higher migration rate compared with FBS-cultured ASC in a transwell assay. Finally, FBS- and PL-cultured ASC had a similar high capacity to differentiate towards cardiomyocytes. In conclusion, this study showed that culturing ASC is more favorable in PL-supplemented medium compared with FBS-supplemented medium

An easy and efficient method for the synthesis of quinoxalines using recyclable and heterogeneous nanomagnetic-supported acid catalyst under solvent-free condition

Synthesis of quinoxalines from o‐phenylenediamines (o‐PDs) with electronically diversified 1,2‐diketones and α‐bromoketones via simple cyclocondensation reaction using an heterogeneous nano‐ϒ‐Fe2O3‐SO3H catalyst has been reported under solvent free condition. Low cost, easy workup, high yield, operational simplicity, less reaction time, environmentally benign nature and catalyst is magnetically retrievable and can be reused up to five catalytic cycles without significant loss in the product yields are the noteworthy features of this protocol

Utilization Pattern of PM-KISAN Benefits

In developing countries like India, the obstacles for development for an economy are large. Such countries' population is mainly dependent on agriculture for their livelihood. It is relic, that the exploitation of landlords and zamindari systems on small and marginal farmers. Even today small and marginal farmers with small holdings are still in the need of development. Due to some market negotiations while selling their output, farmers might face loss and sometimes find difficult to debt repayment, crop diseases, floods and droughts. Because of debt issues large number of farmers have given up their lives. According to the National Crime Report of Bureau (NCRB), the number of farmer suicides in the country has plunged to 11,379 in 2016, 12,360 and 12,602 in 2014 and 2015 respectively. Therefore, to rescue and upliftment of SMFs,’ the central government of India introduced many programs among PM-KISAN Yojana is also one which provides a financial inducement to the farmers through instalments under certain duration gap, since December 1st of 2018. The scheme aims to provide financial support to the small and marginal farmers to get hold of various inputs such as crop health and appropriate yields along with farm income proportionate to the land holdings at the end of each crop. This would also protect them from falling in the clutches of moneylenders for meeting such expenses and ensure their continuance in the farming activities. As of the aim of PM-KISAN, beneficiaries have not been optimum utilization of the scheme financial assistance. So that, the present study objects to analyses the scheme benefit utilization pattern among beneficiaries in Davanagere district of Karnataka. The description of the study relates to Davanagere district particularly and that has planned to take few farmers to analyses the scheme influences on beneficiaries. The information will be collected from beneficiaries directly and will be presented through tabular representation with some analysis followed by interpretation. There are many sources even used by articles, newspapers and government publications