Leczenie nieswoistych chorób zapalnych jelit w czasie ciąży i karmienia

Planowanie ciąży, jej przebieg, poród oraz stan zdrowia dziecka stanowią istotne zagadnienia w opiece nad pacjentami z chorobami zapalnymi jelit. Większość pacjentek wymaga utrzymania leczenia choroby w czasie ciąży i karmienia, czasami konieczne jest wprowadzenie w tym okresie nowych leków. W artykule przedstawiono aktualny stan wiedzy dotyczący bezpieczeństwa terapii w okresie przed i w czasie ciąży oraz w okresie karmienia dziecka, zwrócono również uwagę na konieczność edukacji pacjentów oraz zapewnienia wielospecjalistycznej opieki w przypadku zaostrzenia przebiegu choroby lub wystąpienia jej powikłań

Grocery shopping behaviour in the era of Covid-19 : panel data analysis from convenience store sector in England, Scotland and Wales

To the best of our knowledge this is the first attempt to address the consistencies and inconsistencies between the grocery shopping behaviour shifts in the era of Covid-19 across three devolved nations of the mainland UK. We address the strictness of ‘lockdown style’ closure and containment policies that primarily restrict people’s behaviour (stringency index). We use a unique dataset of transactional data (778,305 observations) drawn from 1,282 convenience stores located in England, Scotland and Wales. Panel data analysis covers the pre-pandemic (Jan 2018 – Feb 2020) and pandemic period (March 2020 – Dec 2020). This research reveals that, despite the consistent decrease of single item transactions and increase of average spend per transaction across England, Scotland and Wales, the dynamics of these shifts in time varies meaningfully. All these shifts highly correlate with the stringency index. Analysis of additional explanatory variables i.e. store size, location, affiliation shows further dimensions

Diagnostic Difficulties in Woman with Crohn’s Disease, Ascites, and Elevated Value of Serum CA125 Antigen

Variety of symptoms and atypical clinical course of Crohn’s disease (CD) often create the need for additional diagnostic procedures. In the described case of woman with CD, there was a suspicion of coexistence of ovarian cancer. This issue is particularly important in patients treated with immunosuppressants and biological agents. The discussion focused on the usefulness of CA125 (cancer antigen 125, mucin 16) serum level estimation in clinical practice and draws attention to the possible reasons for the increase of its value which is not associated to ovarian cancer

Improvement in health-related quality of life after therapy with omeprazole in patients with coronary artery disease and recurrent angina-like chest pain. A double-blind, placebo-controlled trial of the SF-36 survey

<p>Abstract</p> <p>Background</p> <p>Many patients with coronary artery disease (CAD) have overlapping gastroenterological causes of recurrent chest pain, mainly due to gastroesophageal reflux (GER) and aspirin-induced gastrointestinal tract damage. These symptoms can be alleviated by proton pump inhibitors (PPIs). The study addressed whether omeprazole treatment also affects general health-related quality of life (HRQL) in patients with CAD.</p> <p>Study</p> <p>48 patients with more than 50% narrowing of the coronary arteries on angiography without clinically overt gastrointestinal symptoms were studied. In a double-blind, placebo-controlled, cross-over study design, patients were randomized to take omeprazole 20 mg bid or a placebo for two weeks, and then crossed over to the other study arm. The SF-36 questionnaire was completed before treatment and again after two weeks of therapy.</p> <p>Results</p> <p>Patients treated with omeprazole in comparison to the subjects taking the placebo had significantly greater values for the SF-36 survey (which relates to both physical and mental health), as well as for bodily pain, general health perception, and physical health. In comparison to the baseline values, therapy with omeprazole led to a significant increase in the three summarized health components: total SF-36; physical and mental health; and in the following detailed health concept scores: physical functioning, limitations due to physical health problems, bodily pain and emotional well-being.</p> <p>Conclusions</p> <p>A double dose of omeprazole improved the general HRQL in patients with CAD without severe gastrointestinal symptoms more effectively than the placebo.</p

CONSUMER CONFIDENCE AS A DETERMINANT OF HOUSEHOLD PROPENSITY TO SAVE

The following paper elaborates on the significance of saving for the financial stability. The changes in the propensity to save of households in Poland between 1997-2010 are discussed. A regression analysis was carried out in order to test the influence of changes in consumer confidence on the household saving rate. It has been demonstrated that a change in consumer confidence for the positive has a negative impact on the saving rate and a change for the negative contributes to a greater propensity to save

KIERUNKI ZMIAN W PROCESACH OSZCZĘDZANIA GOSPODARSTW DOMOWYCH W JAPONII

Artykuł stanowi przyczynek do ograniczenia niedostatku literatury polskiej poświęconej procesom oszczędzania przez gospodarstwa domowe na świecie poprzez diagnozę kierunków zmian w procesach oszczędzania gospodarstw domowych w Japonii. W artykule wskazano, że stopa oszczędzania japońskich gospodarstw domowych była wysoka zarówno w ujęciu bezwzględnym, jak i w porównaniu z wartościami wskaźnika w innych krajach, jednak od lat 90. występuje silna, długotrwała tendencja spadkowa. W celu wyjaśnienia tego zjawiska zidentyfikowano determinanty zmian w procesach oszczędzania gospodarstw domowych w Japonii. Do najistotniejszych uwarunkowań zaliczono: zmiany demograficzne, zmiany dochodów gospodarstw domowych, zmiany w systemie ubezpieczeń społecznych. Wskazano, że postępujące na niespotykaną skalę starzenie się społeczeństwa będzie negatywnie oddziaływać na stopę oszczędzania gospodarstw domowych

Mental and behavioral disorders in the population of homeless patients admitted to hospital emergency departments

The aim of the study is to identify the most common mental and behavioral disorders diagnosed in homeless patients admitted to hospital emergency departments and to identify performed medical procedures including diagnostic and therapeutic measures in this range

The gastroesophageal acid reflux as a causative factor of paroxysmal atrial fibrillation

The gastroesophageal acid reflux as a causative factor of paroxysmal atrial fibrillation: We present a case of a patient with very frequent episodes of paroxysmal atrial fibrillation (AF) who, besides hypertension and well-controlled post-amiodarone thyreotoxicosis, had no other potential causes of AF. Because of symptoms of gastroesophageal acid reflux, the patient was treated with omeprazole which significantly reduced the frequency of AF episodes. Next, the patient underwent anti-reflux surgery and has now only sporadic recurrences of AF. Our observations suggest that gastroesophageal acid reflux may be a triggering factor of AF

Profile of homeless people in emergency departments

ObjectivesFor homeless people, emergency departments (ED) are the place of medical care and satisfying physiological, safety and social needs. The treatment of the homeless in EDs is a common issue in many countries. The aim of study was to analyze selected parameters of health care to homeless people in EDs. The authors examined the frequency and the seasonality of admissions, their causes, stay duration, insurance status, and the type of radiological diagnostics performed.Material and MethodsA retrospective analysis of stays of homeless patients in 3 EDs in one of the largest cities in Poland in 2013–2015 was carried out. Patients were qualified to the population of homeless people based of their registering in ED. Data was obtained on the total number of homeless patients’ stays in all 3 EDs, which amounted to 3133.ResultsDuring the 3 years of analysis: 1042 homeless individuals were identified staying 3133 times in EDs; 46.3% of the stays concerned uninsured homeless people; 31% were under influence of alcohol. On average, men used ED services 3 times, while women only twice. No significant seasonality of admissions was observed. Homeless people were admitted mainly for mental disorders and head injuries. Radiological tests were performed 1577 times, including 83% being CT scans. On average, women and those >30 stayed in EDs for the shortest time. The hospital wards admitted 9.3% of the patients.ConclusionsAlmost half of homeless patients repeatedly use ED services, regardless of the season. A patient’s stay typically lasts 6 h. Half of them were uninsured. The main reasons for admission include mental and behavioral disorders, mostly due to alcohol use and head injuries. The primary radiological diagnostics used were CT scans

Translation and validation of the inflammatory bowel disease fatigue (IBD-F) patient self-assessment questionnaire

INTRODUCTION: Inflammatory bowel disease (IBD) is a group of chronic gastrointestinal diseases with frequent systemic complications that are incurable according to current knowledge. These diseases adversely affect various areas of life, lowering patients’ quality of life. One of the most frequently reported symptoms is fatigue. AIM: Translation and validation of the IBD-F patient self-assessment scale with a Polish IBD population. MATERIAL AND METHODS: After consent from the author of the questionnaire had been obtained, the questionnaire was translated using the forward- and back-translation method. After arriving at the final Polish version of the questionnaire and ensuring that the questions and statements were comprehensible, the questionnaire was validated with a group of 129 IBD patients. RESULTS: High values of intraclass correlation coefficient (ICC) were achieved for overall results in both parts of the IBD-F questionnaire between test and retest (values exceeding 0.75). A high Cronbach’s α consistency coefficient was achieved for the entire IBD-F questionnaire, both in the test and in the retest (0.968 and 0.975, respectively). Broken down into parts, Cronbach’s α coefficient for Section I (presence and severity of fatigue) of the IBD-F questionnaire was 0.883, and for Section II (impact of fatigue on the person’s life) it was 0.966. All patients evaluating the Polish version of the IBD-F questionnaire deemed the content of the questions comprehensible. CONCLUSIONS: The analysis of the results obtained, the Polish version of the IBD-F questionnaire was considered valid, reliable, and clinically useful