Evaluating unscheduled readmission to emergency department in the early period

Background: The readmission in the early period (RAEP) is defined as the admission of a patient to emergency department (ED) for the second time within 72 hours after discharge from the ED. Aims: The aim of this study was to determine the disease, patient, doctor, and system related causes of RAEP. Study Design: Descriptive study. Methods: This study is a two-stage study that was conducted at Department of Emergency, Gazi University Faculty of Medicine. The causes of RAEP were defined as disease, patient, doctor, and system related causes. Results: A total of 46,800 adult patients admitted to ED during the study period and 779 (1.66%) patients required RAEP. After the exclusion criteria, 429 of these patients were included the study. The most common reasons for RAEP were renal colic in 46 (10.7%) patients. It was detected that 60.4% of the causes of RAEP were related to disease, 20.0% were related to the doctor, 12.1% were related to the patient, and 7.5% were related to the hospital management system. Conclusion: This study revealed that there are patient-, doctor-, and system-related preventable reasons for RAEP and the patients requiring RAEP constitute the high risk group. © 2016 Trakya University Faculty of Medicine

How to Use Natriuretic Peptides in Patients with Heart Failure with Non-Reduced Ejection Fraction?

[No abstract available

Decorin as a new treatment alternative in Peyronie's disease: preliminary results in the rat model.

The purpose of this study is to investigate the effect of decorin, a naturally occurring proteoglycan with anti-transforming growth factor beta (TGF-) activity, on the rat model of Peyronie's disease (PD). Twenty-five adult male Sprague-Dawley rats were divided in three groups: I) TGF- (0.5g) injected (n: 8); II) TGF- injected and decorin treated (n: 8); and III) controls (n: 9). Decorin (0.5g per day) was given with intracavernous injection on the second, third, fourth and fifth day following TGF- injection. All rats underwent electrical stimulation of the cavernous nerve after 6weeks. Intracavernosal and arterial blood pressures were measured during this procedure. Cross-sections of the rat penises were examined using Mason trichrome and H&E stains. Statistical analyses were carried out using one-way anova. Histopathological examinations confirmed the Peyronie's-like condition in TGF--injected rats, which exhibited a thickening of the tunica albuginea (TA), when compared to controls. Disorganisation of collagen on the TA was also prominent in TGF--injected rats, but not in decorin-treated and control rats. Decorin-treated rats showed significantly higher maximal intracavernosal pressure (MIP) responses to cavernous nerve stimulation, when compared to group 1 (P<0.05). Our results indicate that decorin antagonises the effects of TGF- in the rat model of PD and prevents diminished erectile response to cavernous nerve stimulation