Photoallergic sensitivity in patients with dyshidrotic eczema

Dishidrotik ekzema, histolojik olarak spongiotik veziküller ile karakterize, veziküler palmoplantar ekzema grubunda yer alan endojen bir dermatittir. Etyolojisi tam olarak aydınlatılamamakla birlikte deriye temas eden veya oral alınan bazı metallere karşı vücudun bir allerjik yanıtı olduğu düşüncesi nedeniyle hastalara yama testi uygulanması önerilmektedir. Bu çalışmamızda, hastalığın özellikle UV'nin yoğun olduğu ilkbahar yaz aylarında alevlenmesinden yola çıkarak, Avrupa standart test serisi ile fotoyama testinde, etyolojide ekzojen fotoallerjen ve UV'nin etkisini araştırmayı amaçladık. Çalışmamıza klinik ve/veya histopatolojik olarak dishidrotik ekzema tanısı almış olan 30 kişilik hasta ve 30 kişiden oluşan kontrol grubu dahil edildi. Hasta grubunda yama testinde 8 (%26,7) hastada pozitiflik bulunurken, kontrol grubunda 1 (%3,3) kişide pozitiflik vardı. Bu yönden karşılaştırıldığında aralarındaki farkın istatistiksel olarak anlamlı olduğu bulunmuştur (p<0.05). Yama testi pozitiflikleri bir hasta dışında meslekleri ile ilişkilendirilmemiştir. Hasta ve kontrol grubunda fotoyama testinde pozitiflik saptanmamıştır. Sonuç olarak, dishidrotik ekzema etyolojisindeki bilinmezlik devam etmektedir. Çalışmamızda bu hastalarda Avrupa standart test serisi ile uygulanan fotoyama testinde pozitiflik saptamadık. Bu hipotez doğrultusunda daha geniş hasta serileri ile ve fotosensitizan allerjenlerle yapılacak çalışmalara ihtiyaç vardır. Anahtar kelimeler: Dishidrotik ekzema, Fotoyama testiDyshidrotic eczema is an endogenous dermatitis, histologically characterized with spongiotic vesicles, and appearing in vesicular palmoplantar eczema group. With its etiology not fully understood it?s thought that this is an allergic response to some metals contacting to the skin or taken orally, therefore its recommended patch test should be applied to these patients. In this study, consideing this disease especially exacerabates in spring and summer when the UV lights are intense; we intended to investigate exogenous photoallergan and UV effect in etiology ith use the European standart test series in the photopatch test. In our stady 30 patients clinically and/or histopathologically diagnosed as dyshidrotic eczema and 30 persons as the control group were included. In the control group only one patient (%3,3) had positive patch test while in the patient group eight (%26,7) had positive result. When compared using this; the difference between was found to be statistically significant (p<0,05). Patch test positivenesses were not associated with occupation except one patient. In patient and control groups there were no positiveness in photopatch test. In conclusion, the obscurity of the dyshidrotic eczemas etiology is continuing. In our study we did not find positive results in the photopatch test applied with the European standart test series in our patients. Considering this hypothesis; studies done with more extensive patients series and photosensiting allergens are needed. Key words: Dyshidrotic eczema, Photopatch tes

Assessment of fetal right ventricular myocardial performance index changes following intrauterine transfusion

Introduction: Severe fetal anemia may cause cardiac ischemia, reduced contractility, and dysfunction. The purpose of our study is to evaluate right ventricular myocardial performance index (MPI) before and after intrauterine transfusion (IUT) in patients who underwent this procedure because of fetal anemia due to Rh-D alloimmunization. Materials and methods: This prospective cohort study was conducted between January 2018 and June 2019 at Kanuni Sultan Suleyman Research and Training Hospital, Istanbul, Turkey. The pregnant women who were applied IUT because of fetal anemia due to Rh-D alloimmunization in our perinatology clinic were included in the study. Fetal right ventricular MPI before and 24 h after IUT were evaluated. Results: A total of 28 IUTs were performed in 17 pregnant women during the study period. The isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT) values measured before IUT, were found to be significantly longer compared to the ICT and IRT values measured after IUT. The MPI values measured after transfusion was found to be higher than before transfusion. Conclusions: The fetal right ventricular MPI increases 24 h after IUT. This increase in the right ventricular MPI might be used as a marker for predicting adverse fetal outcomes following IUT

6098 sayılı Türk Borçlar Kanunu, Karşılaştırmalı, Notlu, İçtihatlı, Atıflı

6098 sayılı Türk Borçlar Kanunu</p