24 research outputs found
Instantons and the spectral function of electrons in the half-filled Landau level
We calculate the instanton-anti-instanton action in
the gauge theory of the half-filled Landau level. It is found that for a class of interactions between electrons. This means that the instanton-anti-instanton
pairs are confining so that a well defined `charged' composite fermion can
exist. It is also shown that can be used to calculate
the spectral function of electrons from the microscopic theory within a
semiclassical approximation. The resulting spectral function varies as at low
energies.Comment: 13 pages, Plain Tex, MIT-CMT-APR-9
Influence of gauge-field fluctuations on composite fermions near the half-filled state
Taking into account the transverse gauge field fluctuations, which interact
with composite fermions, we examine the finite temperature compressibility of
the fermions as a function of an effective magnetic field ( is the density of electrons) near the half-filled state. It is
shown that, after including the lowest order gauge field correction, the
compressibility goes as for , where . Here we assume that the interaction between
the fermions is given by , where is a dependent constant. This result can be
interpreted as a divergent correction to the activation energy gap and is
consistent with the divergent renormalization of the effective mass of the
composite fermions.Comment: Plain Tex, 24 pages, 5 figures available upon reques
Specific heat and validity of quasiparticle approximation in the half-filled Landau level
We calculate the specific heat of composite fermion system in the half-filled
Landau level. Two different methods are used to examine validity of the
quasiparticle approximation when the two-body interaction is given by (). The singular part of the specific heat
is calculated from the free energy of the gauge field, which is compared with
the specific heat calculated from the quasiparticle approximation via the
singular self-energy correction due to the gauge field fluctuations. It turns
out that two results are in general different and they coincide only for the
case of the Coulomb interaction (). This result supports the fact
that the quasiparticle approximation is valid only for the case of the Coulomb
interaction. It is emphasized that this result is obtained by looking at a
gauge-invariant quantity -- the specific heat.Comment: 8 pages, Revte
Gauge-invariant response functions of fermions coupled to a gauge field
We study a model of fermions interacting with a gauge field and calculate
gauge-invariant two-particle Green's functions or response functions. The
leading singular contributions from the self-energy correction are found to be
cancelled by those from the vertex correction for small and . As a
result, the remaining contributions are not singular enough to change the
leading order results of the random phase approximation. It is also shown that
the gauge field propagator is not renormalized up to two-loop order. We examine
the resulting gauge-invariant two-particle Green's functions for small and
, but for all ratios of and we conclude that they can
be described by Fermi liquid forms without a diverging effective mass.Comment: Plain Tex, 35 pages, 5 figures available upon request, Revised
Version (Expanded discussion), To be published in Physical Review B 50,
(1994) (December 15 issue
Quantum Boltzmann equation of composite fermions interacting with a gauge field
We derive the quantum Boltzmann equation (QBE) of composite fermions at/near
the state using the non-equilibrium Green's function technique. The
lowest order perturbative correction to the self-energy due to the strong gauge
field fluctuations suggests that there is no well defined
Landau-quasi-particle. Therefore, we cannot assume the existence of the
Landau-quasi-particles {\it a priori} in the derivation of the QBE. Using an
alternative formulation, we derive the QBE for the generalized Fermi surface
displacement which corresponds to the local variation of the chemical potential
in momentum space. {}From this QBE, one can understand in a unified fashion the
Fermi-liquid behaviors of the density-density and the current-current
correlation functions at (in the long wave length and the low
frequency limits) and the singular behavior of the energy gap obtained from the
finite temperature activation behavior of the compressibility near .
Implications of these results to the recent experiments are also discussed.Comment: 44 pages, Plain Tex, 5 figures (ps files) available upon reques
Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial
Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials.
Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure.
Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen.
Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049
Investigating the Mechanism of Strong Roof Weighting and Support Resistance Near Main Withdrawal Roadway in Large-Height Mining Face
Aiming at investigating the strong roof weighting when the large height mining face is nearing the main withdrawal roadway, the 52,304 working face (WF) nearly through the main withdrawal roadway mining in a colliery of Shendong coalfield was taken as the research background. The ground pressure, roof structure, and superposition effect of stress in the last mining stage were studied by field measurement, physical simulation, and numerical calculations. The obtained results demonstrated that the main roof formed the “long step voussoir beam” structure under the influence of the main withdrawal roadway. The superposition effect of the front abutment pressure of the WF and the concentrated stress of the main withdrawal roadway caused the stress asymmetrical distribution on the two sides -level hard rock straof the main withdrawal roadway, and the stability of the pillar on the mining side decreases. The initial average periodic weighting interval was 20.7 m. While the WF approaches the main withdrawal roadway, the pillar near the WF of the main withdrawal roadway collapsed, the main roof was broken ahead of the WF, and the actual roof control distance of support and the periodic weighting interval increased by 2.56 and 1.26 times the normal state, respectively. Consequently, the “static load” of the immediate roof and the “dynamic load” of the sliding unsteadiness of the long step voussoir beam increased. The structural model of the “long step voussoir beam” under the superposition of “static and dynamic load” was established concerning those results, and an expression was proposed to compute the support resistance. Meanwhile, the mechanism of strong roof weighting was revealed when the WF was nearly through the main withdrawal roadway. The research conclusion is expected to provide a guideline for the safe withdrawal of the large-height mining faces under similar conditions
Research on Roof Load Transfer by Passing Coal Pillar of Working Face in Shallow Buried Closely Multiple-Seam
The dynamic load effect of supports is mainly caused by the movement of the roof structure and the load transfer of overburden. In view of the practice issue that the phenomenon of strong ground pressure is easy to happen, when the working face of the lower coal seam passes the inclined coal pillar in shallow buried closely multiple-seam, it will lead to supprot damaged. This paper takes the mining of over-inclined coal pillars in the 22410 working face of the Bulianta Coal Mine as the background, based on the research method combining the field measurement, physical simulation experiment, and numerical calculation, the evolution law of the front abutment pressure (FAP) and roof weighting in mining under the inclined coal pillar is analyzed, and the mechanism of the stress transfer of the inclined coal pillar and the dynamic load of the support is revealed. The research shows that the concentrated stress of the coal pillar is jointly borne by the front coal wall of the working face and the interburden structure above the support. The vertical stress transmitted from the coal pillar to the floor acts on the key blocks of the interburden of the lower coal seam, which causes strong pressure and dynamic load effect, such as roof structure cut-off. The periodic breaking of the key stratum of the interburden leads to the development height and range of the cracks increasing stepwise. The partition characteristics of the mutual transformation of the interburden stress, the FAP, and the working resistance (WR) by passing the coal pillar stage are revealed, which is divided into three stages and four regions. With the working face passing through the inclined coal pillar, the influence area of the concentrated stress of the coal pillar is reduced, and the peak stress of the coal pillar is gradually transferred to the outside of the coal pillar. When the working face is 5 m away from the coal pillar, the peak of FAP and WR reaches the maximum values, the roof is cutting along the peak stress line, and the working face has a strong weighting phenomenon. The research results are consistent with the field measurement results, providing a reference for the mining of working faces under similar conditions
Serum klotho: a potential predictor of cerebrovascular disease in hemodialysis patients
Abstract Background Hemodialysis patients suffer from a serious threat of cerebrovascular disease. Klotho, as an aging-suppressor gene, contributes to protect on vascular calcification and oxidative stress, which are the risk factors of cerebrovascular disease. The purpose of the present study is to determine the relationship between serum klotho and cerebrovascular disease in patients receiving hemodialysis. Methods Serum klotho levels of hemodialysis patients were measured by ELISA. Cerebrovascular diseases were diagnosed by CT or MRI scans. The cognitive function of hemodialysis patients with cerebrovascular disease were evaluated with a neuropsychological battery assessing domains of global cognition verbal memory, spatial memory, executive function and verbal fluency. Results Eighty-eight patients were included, 57 ± 14 years, 63.64% male, 52.27% older than 60 years. Twenty-eight participants had cerebrovascular disease (23 cases had cerebral infarction, 5 cases had cerebral hemorrhage). The average level of serum klotho of all participants was 119.10 ± 47.29 pg/ml. The serum klotho level was significantly associated with cerebrovascular disease in hemodialysis patients (HR(95%CI) = 0.975(0.960–0.990), p = 0.001). The optimal cut-off value of serum klotho for predicting cerebrovascular disease in hemodialysis patients was 137.22 pg/ml, with a specificity of 96.4% and a sensitivity of 46.7%. But serum klotho was not an independent risk factor of cognitive impairment for hemodialysis patients with cerebrovascular disease (HR((95%CI) = 1.002(0.986–1.018), p = 0.776) or with cerebral infarction (HR(95%CI) = 1.005(0.987–1.023), p = 0.576). Conclusions The serum klotho level is a potential predictor of cerebrovascular disease in hemodialysis patients, but it is not an independent risk factor of cognitive impairment for hemodialysis patients with cerebrovascular disease
CoSe2-decorated NbSe2 nanosheets fabricated via cation exchange for Li storage
Though 2D transition metal dichalcogenides have attracted a lot of attention in energy-storage applications, the applications of NbSe2 for Li storage are still limited by the unsatisfactory theoretical capacity and uncontrollable synthetic approaches. Herein, a controllable oil-phase synthetic route for preparation of NbSe2 nanoflowers consisted of nanosheets with a thickness of ∼10 nm is presented. Significantly, a part of NbSe2 can be further replaced by orthorhombic CoSe2 nanoparticles via a post cation exchange process, and the predominantly 2D nanosheet-like morphology can be well-maintained, resulting in the formation of CoSe2-decorated NbSe2 (denoted as CDN) nanosheets. More interestingly, the CDN nanosheets exhibit excellent lithium-ion battery performance. For example, it achieves a highly reversible capacity of 280 mAh g-1 at 10 A g-1 and long cyclic stability with specific capacity of 364.7 mAh g-1 at 5 A g-1 after 1500 cycles, which are significantly higher than those of reported pure NbSe2.NRF (Natl Research Foundation, S’pore)MOE (Min. of Education, S’pore)Accepted versio