Treatment of depression during pregnancy: a protocol for systematic review and meta-analysis

IntroductionMajor Depressive Disorder (MDD) is a chronic, recurrent, and highly prevalent disease that is associated with significant functional disability. During pregnancy, the prevalence of the disease is approximately 20%, with 12% of these, requiring treatment to avoid important negative consequences for the mother-baby binomial. Risk-benefit assessment of the use of antidepressants during pregnancy is mandatory, in addition to knowledge of the long-term effects of prenatal exposure to these drugs in the offspring. In this study, we will perform an updated systematic review and meta-analysis to explore the treatment of depression during pregnancy, along with its effectiveness, safety, and possible harm to women and children.Materials and methodsWe will search for publications in the following databases: Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, Web of Science, Scopus, Lilacs, and PsycINFO. The reference lists of the included studies will be manually reviewed to identify potentially relevant studies. There will be no restrictions on language or date of publication. Quality assessment of the included studies will be performed independently according to the Cochrane Risk of Bias (RoB2) instrument. To assess the certainty of the findings’ body of evidence, we will use the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. This study aimed to ascertain the efficacy and safety of antidepressants in pregnant women and children.Ethics and disseminationEthical approval was not required as individual patient data were not collected. Dissemination: Plan to publish a systematic review in an open-access medical journal at the end of the process.Systematic Review RegistrationPROSPERO, CRD42023447694

Guia de saúde do servidor: orientações para gestores da UFSC

E-bookO Guia de Saúde do Servidor: orientações para gestores da UFSC traz uma compilação de informações básicas e práticas sobre o processo de saúde e adoecimento no trabalho, especialmente voltado para as questões envolvendo a saúde mental. Ele tem como finalidade sensibilizar e orientar os gestores da Universidade Federal de Santa Catarina (UFSC) no intuito de adotar medidas preventivas voltadas para a qualidade de vida no trabalho e de tomar as providências necessárias no caso de identificação de servidores docentes e técnico-administrativos em educação adoecidos. É comum o surgimento de muitas dúvidas nos gestores sobre como lidar com situações de adoecimento mental no trabalho. Por exemplo, saber quais comportamentos e sinais podem indicar que um servidor está em sofrimento/adoecido, quando e como demonstrar apoio ao servidor, que tipos de ações podem ser desenvolvidas no ambiente de trabalho para prevenir o adoecimento, onde encontrar apoio/orientações na UFSC sobre as questões de saúde do servidor, entre outras. Assim, este guia foi pensado para oferecer algumas respostas para esses e outros questionamentos, de modo a facilitar a atuação dos gestores. Destaca-se que o gestor tem um papel fundamental perante a sua equipe e a adoção de medidas adequadas pode ser o diferencial tanto para a manutenção de um ambiente saudável quanto para a recuperação e a reinserção do servidor no trabalho

Do Tibete à Índia - Pobreza, mistério e fé

TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Comunicação e Expressão. Jornalismo.Grande reportagem em foto sobre o Tibete, o Nepal e a Índi

Che - Trajetória do Mito

1997 foi a data de aniversário de 30 anos de morte de Che Guevara. O mundo hoje parece ter mais presente do que nunca a imagem e os ideais de igualdade social do líder revoluncionário. Há uma preocupação em recuperar seus pensamentos políticos e econômicos, como também sua trajetória de guerrilhas pela América Latina e África

Dialectical Behavior Therapy as an intervention for Treatment Resistant Depression in adults: A protocol for systematic review and meta-analysis.

BackgroundMajor Depressive Disorder is a long-term, recurring, and very common illness that is associated with a significant decline in functional ability. The gold-standard method of treating depression is pharmacotherapy, which involves the use of antidepressant medications either alone or in various combinations. However, approximately 30% of Major Depressive Disorder patients suffer from Treatment Resistant Depression, a more severe condition that has a profound impact on patients' lives. Our study aims to conduct the first comprehensive review and meta-analysis to assess the effectiveness and safety of adding Dialectical Behavior Therapy to antidepressant medications compared to groups using pharmacotherapy alone as an intervention for adults with Treatment Resistant Depression.Materials and methodsWe will search for publications in the following databases: Cochrane Central Register of Controlled Trials, MEDLINE, Embase, Lilacs, Web of Science, and PsycINFO. We will manually review the reference lists of the included studies to identify potentially relevant studies. There will be no restrictions on the language or publication date. Quality assessment of the included studies will be performed independently according to the Cochrane Risk of Bias instrument. To assess the certainty of the findings' body of evidence, we will use the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. This study aims to determine the effectiveness and safety of Dialectical Behavior Therapy as an intervention for Treatment Resistant Depression in adults.Ethics and disseminationEthical approval was not required as individual patient data was not obtained. Our intention is to publish the systematic review in a medical journal that offers open access upon completion of the process.Trial registrationPROSPERO registration number CRD42023406301. Registered on March 24, 2023