Synthesis and NOx removal performance of anatase S-TiO2/g-CN heterojunction formed from dye wastewater sludge.

In this study, sludges generated from Ti-based flocculation of dye wastewater were used to retrieve photoactive titania (S-TiO2). It was heterojunctioned with graphitic carbon nitride (g-CN) to augment photoactivity under UV/visible light irradiance. Later the as-prepared samples were utilized to remove nitrogen oxides (NOx) in the atmospheric condition through photocatalysis. Heterojunction between S-TiO2 and g-CN was prepared through facile calcination (@550 °C) of S-TiO2 and melamine mix. Advanced sample characterization was carried out and documented extensively. Successful heterojunction was confirmed from the assessment of morphological and optical attributes of the samples. Finally, the prepared samples' level of photoactivity was assessed through photooxidation of NOx under both UV and visible light irradiance. Enhanced photoactivity was observed in the prepared samples irrespective of the light types. After 1 h of UV/visible light-based photooxidation, the best sample STC4 was found to remove 15.18% and 9.16% of atmospheric NO, respectively. In STC4, the mixing ratio of S-TiO2, to melamine was maintained as 1:3. Moreover, the optical bandgap of STC4 was found as 2.65 eV, where for S-TiO2, it was 2.83 eV. Hence, the restrained rate of photogenerated charge recombination and tailored energy bandgap of the as-prepared samples were the primary factors for enhancing photoactivity

Evaluation of coupled finite element/meshfree method for a robust full-scale crashworthiness simulation of railway vehicles

The crashworthiness of a railway vehicle relates to its passive safety performance. Due to mesh distortion and difficulty in controlling the hourglass energy, conventional finite element methods face great challenges in crashworthiness simulation of large-scale complex railway vehicle models. Meshfree methods such as element-free Galerkin method offer an alternative approach to overcome those limitations but have proved time-consuming. In this article, a coupled finite element/meshfree method is proposed to study the crashworthiness of railway vehicles. A representative scenario, in which the leading vehicle of a high-speed train impacts to a rigid wall, is simulated with the coupled finite element/element-free Galerkin method in LS-DYNA. We have compared the conventional finite element method and the coupled finite element/element-free Galerkin method with the simulation results of different levels of discretization. Our work showed that coupled finite element/element-free Galerkin method is a suitable alternative of finite element method to handle the nonlinear deformation in full-size railway vehicle crashworthiness simulation. The coupled method can reduce the hourglass energy in finite element simulation, to produce robust simulation

Nonlinear disturbance observer-based control for multi-input multi-output nonlinear systems subject to mismatching condition

This article was published in the serial International Journal of Control [© Taylor and Francis] and the definitive version is available at: http://www.tandfonline.com/doi/abs/10.1080/00207179.2012.675520For a multi-input multi-output (MIMO) nonlinear system, the existing disturbance observer-based control (DOBC) only provides solutions to those whose disturbance relative degree (DRD) is higher than or equal to its input relative degree. By designing a novel disturbance compensation gain matrix, a generalised nonlinear DOBC method is proposed in this article to solve the disturbance attenuation problem of the MIMO nonlinear system with arbitrary DRD. It is shown that the disturbances are able to be removed from the output channels by the proposed method with appropriately chosen control parameters. The property of nominal performance recovery, which is the major merit of the DOBCs, is retained with the proposed method. The feasibility and effectiveness of the proposed method are demonstrated by simulation studies of both the numerical and application examples

Sulfuric acid treated G-CN as a precursor to generate high-efficient G-CN for hydrogen evolution from water under visible light irradiation

Modifying the physical, chemical structures of graphitic carbon nitride (g-CN) to improve its optoelectronic properties is the most efficient way to meet a high photoactivity for clean and sustainable energy production. Herein, a higher monomeric precursor for synthesizing improved micro-and electronic structure possessing g-CN was prepared by high-concentrated sulfuric acid (SA) treatment of bulk type g-CN (BCN). Several structural analyses show that after the SA treatment of BCN, the polymeric melon-based structure is torn down to cyameluric or cyanuric acid-based material. After re-polycondensation of this material as a precursor, the resulting g-CN has more condensed microstructure, carbon and oxygen contents than BCN, indicating that C, O co-doping by corrosive acid of SA. This g-CN shows a much better visible light absorption and diminished radiative charge recombination by the charge localization effect induced by heteroatoms. As a result, this condensed C, O co-doped g-CN shows the enhanced photocatalytic hydrogen evolution rate of 4.57 µmol/h from water under the visible light (>420 nm) by almost two times higher than that of BCN (2.37 µmol/h). This study highlights the enhanced photocatalytic water splitting performance as well as the provision of the higher monomeric precursor for improved g-CN

Genetic determinants of co-accessible chromatin regions in activated T cells across humans.

Over 90% of genetic variants associated with complex human traits map to non-coding regions, but little is understood about how they modulate gene regulation in health and disease. One possible mechanism is that genetic variants affect the activity of one or more cis-regulatory elements leading to gene expression variation in specific cell types. To identify such cases, we analyzed ATAC-seq and RNA-seq profiles from stimulated primary CD4+ T cells in up to 105 healthy donors. We found that regions of accessible chromatin (ATAC-peaks) are co-accessible at kilobase and megabase resolution, consistent with the three-dimensional chromatin organization measured by in situ Hi-C in T cells. Fifteen percent of genetic variants located within ATAC-peaks affected the accessibility of the corresponding peak (local-ATAC-QTLs). Local-ATAC-QTLs have the largest effects on co-accessible peaks, are associated with gene expression and are enriched for autoimmune disease variants. Our results provide insights into how natural genetic variants modulate cis-regulatory elements, in isolation or in concert, to influence gene expression

The publication of ethically uncertain research: attitudes and practices of journal editors

<p>Abstract</p> <p>Background</p> <p>Publication of ethically uncertain research occurs despite well-published guidelines set forth in documents such as the Declaration of Helsinki. Such guidelines exist to aide editorial staff in making decisions regarding ethical acceptability of manuscripts submitted for publication, yet examples of ethically suspect and uncertain publication exist. Our objective was to survey journal editors regarding practices and attitudes surrounding such dilemmas.</p> <p>Methods</p> <p>The Editor-in-chief of each of the 103 English-language journals from the 2005 Abridged Index Medicus list publishing original research were asked to complete a survey sent to them by email between September-December 2007.</p> <p>Results</p> <p>A response rate of 33% (n = 34) was obtained from the survey. 18% (n = 6) of respondents had published ethically uncertain or suspect research within the last 10 years. 85% (n = 29) of respondents stated they would always reject ethically uncertain articles submitted for publication on ethical grounds alone. 12% (n = 4) of respondents stated they would approach each submission on a case-by-case basis. 3% (n = 1) stated they would be likely to publish such research, but only with accompanying editorial. Only 38% (n = 13) give reviewers explicit instruction to reject submissions on ethical grounds if found wanting.</p> <p>Conclusions</p> <p>Editorial compliance with the Declaration of Helsinki in rejecting research that is conducted unethically was difficult to ascertain because of a poor response rate despite multiple attempts using different modalities. Of those who did respond, the majority do reject ethically suspect research but few explicitly advise reviewers to do so. In this study editors did not take advantage of the opportunity to describe their support for the rejection of the publication of unethical research.</p