Employees’ Financial Insecurity and Health: The Underlying Role of Stress and Work–Family Conflict Appraisals

Data from two longitudinal samples were utilized to elucidate underlying mechanisms of the well‐established relationship between financial insecurity and health outcomes, stemming from the theoretical rationale of conservation of resources and cognitive appraisal theories. Study 1 (n = 80) consisted of low‐wage food manufacturing employees working full time, while Study 2 (n = 331) was consisted of a larger, heterogeneous sample of full‐time workers representing multiple occupations. Respondents were surveyed on financial insecurity, work‐to‐family conflict (WFC), stress, and health outcomes at two time periods, 3 months apart. Results across our studies provided support for the direct effects of financial insecurity on WFC and stress. In addition, appraisals of WFC and stress serve as significant mediators of the relationship between financial insecurity and health outcomes, including a significant overall lagged effect across time, and perceived stress accounting for the largest proportion of variance in the lagged relationship among Time 1 financial insecurity and Time 2 health outcomes. Besides support for conservation of resources and cognitive appraisal theories, practically, our studies suggest that workplace initiatives to reduce financial insecurity could positively influence employees’ work–family, stress, and health experiences

Vibrational overtone initiated unimolecular dissociation of HOCH_2OOH and HOCD_2OOH: Evidence for mode selective behavior

The vibrational overtone induced unimolecular dissociation of HMHP (HOCH2OOH) and HMHP-d2 (HOCD2OOH) into OH and HOCH2O (HOCD2O) fragments is investigated in the region of the 4nuOH and 5nuOH bands. The unimolecular dissociation rates in the threshold region, corresponding to the 4nuOH band, exhibit measurable differences associated with excitation of the OH stretch of the alcohol versus the peroxide functional group, with the higher energy alcohol OH stretching state exhibiting a slower dissociation rate compared to the lower energy peroxide OH stretch in both HMHP and HMHP-d2. Predictions using the Rice–Ramsperger–Kassel–Marcus theory give rates that are in reasonably good agreement with the measured dissociation rate for the alcohol OH stretch but considerably differ from the measured rates for the peroxide OH stretch in both isotopomers. The present results are interpreted as suggesting that the extent of intramolecular vibrational energy redistribution (IVR) is different for the two OH stretching states associated with the two functional groups in HMHP, with IVR being substantially less complete for the peroxide OH stretch. Analysis of the OH fragment product state distributions in conjunction with phase-space theory simulation gives a D0 value of 38±0.7 kcal/mole for breaking the peroxide bond in HMHP

Circum-Arctic Late Tertiary/Early Pleistocene Stratigraphy And Environments - A Preface

...During the 1980s the Geological Survey of Canada (GSC) and the U.S. Geological Survey (USGS) initiated a program of joint workshops and cooperative field excursions. The first meeting took place in Calgary, Alberta, in 1984. It dealt with correlation of Quaternary deposits in northwestern North America, but touched on the Tertiary. A second GSC/USGS workshop in early 1987 concerned the Quaternary history of interior basins of Alaska and Canada, but once again the Tertiary became an item of discussion because some of the basins contain a thick sequence of Pliocene and Miocene sediments. It was apparent from the questions that arose at these meetings that there was a need for a dedicated forum on the late Tertiary. The authors organized and convened a workshop with that theme in Denver, Colorado, in October 1987. The papers in this special issue are based on presentations and discussions at that meeting. ..

Valuing Academic Perspectives

First paragraph: This report summarises a number of evaluative studies carried out in the neighbourhood of Wester Hailes, Edinburgh in the summer of 2014 by a team of academics, as part of a wider Arts and Humanities Research Council funded Connected Communities project Valuing Different Perspectives (VDP).1 The overall project sought to use a range of evaluative perspectives to the study of a number of previous AHRC Connected Communities projects: Community Hacking 2.0, Ladders to the Clouds, and the Communities Within Spaces of Flows projects.2 The projects produced diverse outputs for the local community: a totem pole; a social history walking "code book"; wall plaques (in preparation); the renewal of the local newspaper The Wester Hailes Sentinel as an online ‘hyper-local' news source, The Digital Sentinel; and a local partnership called Our Place in Time. The earlier Connected Communities projects also supported the local housing association (Prospect Community Housing [PCHA]) in continuing their use of the social history Facebook page From There to Here

Doing and evaluating community research - A process and outcomes approach for communities and researchers

First paragraph: This guide aims to help community partners and academics maximise the benefits of research that is coproduced between communities and academic researchers based in a university. It is divided into three parts: - Learning points - The research story - themes and lessons - How to evaluate The text is hyperlinked for easy access for those who are reading the electronic version. The page numbers in the learning points above take you to the relevant text, as does the underlined text in this section

The TriTryp Phosphatome: analysis of the protein phosphatase catalytic domains

<p>Abstract</p> <p>Background</p> <p>The genomes of the three parasitic protozoa <it>Trypanosoma cruzi</it>, <it>Trypanosoma brucei </it>and <it>Leishmania major </it>are the main subject of this study. These parasites are responsible for devastating human diseases known as Chagas disease, African sleeping sickness and cutaneous Leishmaniasis, respectively, that affect millions of people in the developing world. The prevalence of these neglected diseases results from a combination of poverty, inadequate prevention and difficult treatment. Protein phosphorylation is an important mechanism of controlling the development of these kinetoplastids. With the aim to further our knowledge of the biology of these organisms we present a characterisation of the phosphatase complement (phosphatome) of the three parasites.</p> <p>Results</p> <p>An ontology-based scan of the three genomes was used to identify 86 phosphatase catalytic domains in <it>T. cruzi</it>, 78 in <it>T. brucei</it>, and 88 in <it>L. major</it>. We found interesting differences with other eukaryotic genomes, such as the low proportion of tyrosine phosphatases and the expansion of the serine/threonine phosphatase family. Additionally, a large number of atypical protein phosphatases were identified in these species, representing more than one third of the total phosphatase complement. Most of the atypical phosphatases belong to the dual-specificity phosphatase (DSP) family and show considerable divergence from classic DSPs in both the domain organisation and sequence features.</p> <p>Conclusion</p> <p>The analysis of the phosphatome of the three kinetoplastids indicates that they possess orthologues to many of the phosphatases reported in other eukaryotes, including humans. However, novel domain architectures and unusual combinations of accessory domains, suggest distinct functional roles for several of the kinetoplastid phosphatases, which await further experimental exploration. These distinct traits may be exploited in the selection of suitable new targets for drug development to prevent transmission and spread of the diseases, taking advantage of the already extensive knowledge on protein phosphatase inhibitors.</p