19 research outputs found
Prospective, Unmasked Evaluation of the iStent® Inject System for Open-Angle Glaucoma: Synergy Trial
Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol
Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis
<div><p>Objective</p><p>To examine differences in individual retinal layer thicknesses measured by spectral domain optical coherence tomography (SD-OCT) (Spectralis<sup>®</sup>) produced with age and according to sex.</p><p>Design</p><p>Cross-sectional, observational study.</p><p>Methods</p><p>The study was conducted in 297 eyes of 297 healthy subjects aged 18 to 87 years. In one randomly selected eye of each participant the volume and mean thicknesses of the different macular layers were measured by SD-OCT using the instrument's macular segmentation software.</p><p>Main outcome measures</p><p>Volume and mean thickness of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), retinal pigmentary epithelium (RPE) and photoreceptor layer (PR).</p><p>Results</p><p>Retinal thickness was reduced by 0.24 μm for every one year of age. Age adjusted linear regression analysis revealed mean GCL, IPL, ONL and PR thickness reductions and a mean OPL thickness increase with age. Women had significantly lower mean GCL, IPL, INL, ONL and PR thicknesses and volumes and a significantly greater mRNFL volume than men.</p><p>Conclusion</p><p>The thickness of most retinal layers varies both with age and according to sex. Longitudinal studies are needed to determine the rate of layer thinning produced with age.</p></div
Scatterplots of simple linear regression between age and mean mRNFL, GCL, IPL, INL, OPL, ONL, PR and RPE thickness recorded in 297 subjects.
<p>Scatterplots of simple linear regression between age and mean mRNFL, GCL, IPL, INL, OPL, ONL, PR and RPE thickness recorded in 297 subjects.</p
Simple linear regression between age and mean retinal layer thickness and volume for the study population of 297 subjects.
<p>Simple linear regression between age and mean retinal layer thickness and volume for the study population of 297 subjects.</p
Spectralis segmentation of the retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), retinal pigmentary epithelium (RPE) and photoreceptor layer (PR).
<p>Spectralis segmentation of the retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), retinal pigmentary epithelium (RPE) and photoreceptor layer (PR).</p
Simple linear regression between age and retinal layer thickness of the central, inner and outer circle for the study population of 297 subjects.
<p>Simple linear regression between age and retinal layer thickness of the central, inner and outer circle for the study population of 297 subjects.</p
Ocular Redness Measured with the Keratograph 5M in Patients Using Anti-Glaucoma Eye Drops
Preliminary Study of the Differences in Optic Nerve Head Hemoglobin Measures Between Patients With and Without Childhood Glaucoma
The mean nasal outer RNFL thickness in healthy Caucasian subjects as a function of axial length.
<p>AL = axial length.</p