Geographic variation in morphometrics, molt, and migration suggests ongoing subspeciation in Pacific Golden-Plovers (<i>Pluvialis fulva</i>)

Breeding Pacific Golden-Plovers (Pluvialis fulva) cover 140 longitudinal degrees of Arctic tundra. Having examined 557 museum skins from across this huge distributional range, we conclude that Pacific Golden-Plovers breeding in Alaska are structurally larger than those breeding in Siberia, especially in wing length. Birds from Alaska also have more pointed wings and almost always postpone the initiation of primary molt until they reach their winter quarters, whereas many Siberian birds start primary molt in the breeding areas. These differences could have been favored by the longer transoceanic flights followed by the Alaskan populations to nonbreeding destinations in the Pacific Islands. We propose that the Alaskan and Siberian breeding birds be distinguished as distinct flyway populations to be used in conservation assessments by the international conservation community

Concurrentiemonitor boomkwekerij

Het rapport Concurrentiemonitor boomkwekerij beschrijft de ontwikkelingen in de Nederlandse boomkwekerijsector en vergelijkt de Nederlandse concurrentiepositie met die van de belangrijkste concurrerende landen: Italië, België, Duitsland en Spanje. Het onderzoek is in grote lijnen uitgevoerd op basis van beschikbaar statistisch bronnenmateriaal. Om enige verdieping aan te kunnen brengen in de analyse heeft een expertbijeenkomst plaatsgevonden met kwekers en handelaren die goed zicht hebben op de concurrentiekracht van de Nederlandse sector

Homocysteine levels and treatment effect in the prospective study of pravastatin in the elderly at risk

Objectives: To assess the effect of preventive pravastatin treatment on coronary heart disease (CHD) morbidity and mortality in older persons at risk for cardiovascular disease (CVD), stratified according to plasma levels of homocysteine.&lt;p&gt;&lt;/p&gt; Design: A post hoc subanalysis in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER), started in 1997, which is a double-blind, randomized, placebo-controlled trial with a mean follow-up of 3.2 years.&lt;p&gt;&lt;/p&gt; Setting: Primary care setting in two of the three PROSPER study sites (Netherlands and Scotland).&lt;p&gt;&lt;/p&gt; Participants: Individuals (n = 3,522, aged 70–82, 1,765 male) with a history of or risk factors for CVD were ranked in three groups depending on baseline homocysteine level, sex, and study site.&lt;p&gt;&lt;/p&gt; Intervention: Pravastatin (40 mg) versus placebo.&lt;p&gt;&lt;/p&gt; Measurements: Fatal and nonfatal CHD and mortality.&lt;p&gt;&lt;/p&gt; Results: In the placebo group, participants with a high homocysteine level (n = 588) had a 1.8 higher risk (95% confidence interval (CI) = 1.2–2.5, P = .001) of fatal and nonfatal CHD than those with a low homocysteine level (n = 597). The absolute risk reduction in fatal and nonfatal CHD with pravastatin treatment was 1.6% (95% CI = −1.6 to 4.7%) in the low homocysteine group and 6.7% (95% CI = 2.7–10.7%) in the high homocysteine group (difference 5.2%, 95% CI = 0.11–10.3, P = .046). Therefore, the number needed to treat (NNT) with pravastatin for 3.2 years for benefit related to fatal and nonfatal CHD events was 14.8 (95% CI = 9.3–36.6) for high homocysteine and 64.5 (95% CI = 21.4–∞) for low homocysteine.&lt;p&gt;&lt;/p&gt; Conclusion: In older persons at risk of CVD, those with high homocysteine are at highest risk for fatal and nonfatal CHD. With pravastatin treatment, this group has the highest absolute risk reduction and the lowest NNT to prevent fatal and nonfatal CHD.&lt;p&gt;&lt;/p&gt

The incidence and risk factors for new onset atrial fibrillation in the PROSPER study

Aims Atrial fibrillation/flutter (AF) is the most common arrhythmia in older people. It associates with reduced exercise capacity, increased risk of stroke, and mortality. We aimed to determine retrospectively whether pravastatin reduces the incidence of AF and whether any electrocardiographic measures or clinical conditions might be risk factors for its development. Methods and results The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) was a randomized, double-blind controlled trial that recruited 5804 individuals aged 70-82 years with a history of, or risk factors for, vascular disease. A total of 2891 were allocated to pravastatin and 2913 to placebo; mean follow-up was 3.2 years. Electrocardiograms (ECGs), which were recorded at baseline, annually thereafter, and at run-out, were processed by computer and reviewed manually. In all, 264 of 2912 (9.1%) of the placebo group and 283 of 2888 (9.8%) of the pravastatin-treated group developed AF [hazard ratio 1.08 (0.92,1.28), P = 0.35)]. Multivariate analysis showed that PR and QTc intervals, age, left ventricular hypertrophy, and ST-T abnormalities were related to development of AF after adjustment for many variables including alcohol consumption, which itself was univariately predictive of developing AF. Previous myocardial infarction on the ECG was not a risk factor. A history of vascular disease was strongly linked with developing AF but not diabetes and hypertension. Conclusion Pravastatin does not reduce the incidence of AF in older people at risk of vascular disease, at least in the short-medium term. Risk factors for AF include older age, prolongation of PR or QTc intervals, left ventricular hypertrophy, and ST-T abnormalities on the EC

Zzp'ers in beeld : een inventarisatie in de agrarische sector

Dit rapport schetst een beeld van zzp (zelfstandige zonder personeel) in de agrarische sector. In deze inventariserende studie zijn de voor% en nadelen van deze relatief nieuwe vorm van arbeid beschreven en is ingezoomd op de kansen die zzp biedt voor bepaalde doelgroepen. Het rapport omvat ook kwantitatieve informatie over de inzet van zzp'ers in de land% en tuinbouw. Verder is een aantal inhoudelijke thema's uitgewerkt, waaronder werving van zzp'ers/opdrachten, regelgeving, certificering en sociale zekerheid. Het rapport is gebaseerd op een deskstudie en een praktijkinventarisati