131 research outputs found
Simulating reflected light coronagraphy of Earth-like exoplanets with a large IR/O/UV space telescope: impact and calibration of smooth exozodiacal dust
Observing Earth-like exoplanets orbiting within the habitable zone of
Sun-like stars and studying their atmospheres in reflected starlight requires
contrasts of in the visible. At such high contrast,
starlight reflected by exozodiacal dust is expected to be a significant source
of contamination. Here, we present high-fidelity simulations of coronagraphic
observations of a synthetic Solar System located at a distance of 10 pc and
observed with a 12 m and an 8 m circumscribed aperture diameter space telescope
operating at 500 nm wavelength. We explore different techniques to subtract the
exozodi and stellar speckles from the simulated images in the face-on, the 30
deg inclined, and the 60 deg inclined case and quantify the remaining
systematic noise as a function of the exozodiacal dust level of the system. We
find that in the face-on case, the exozodi can be subtracted down to the photon
noise limit for exozodi levels up to zodi using a simple toy model
for the exozodiacal disk, whereas in the 60 deg inclined case this only works
up to zodi. We also investigate the impact of larger wavefront errors
and larger system distance, finding that while the former have no significant
impact, the latter has a strong (negative) impact. Ultimately, we derive a
penalty factor as a function of the exozodi level and system inclination that
should be considered in exoplanet yield studies as a realistic estimate for the
excess systematic noise from the exozodi.Comment: 20 pages, 9 figures, accepted for publication in A
Multimode simulations of a wide field of view double-Fourier far-infrared spatio-spectral interferometer
In the absence of 50-m class space-based observatories, subarcsecond astronomy spanning the full far-infrared wavelength range will require space-based long-baseline interferometry. The long baselines of up to tens of meters are necessary to achieve subarcsecond resolution demanded by science goals. Also, practical observing times command a field of view toward an arcminute (1′) or so, not achievable with a single on-axis coherent detector. This paper is concerned with an application of an end-to-end instrument simulator PyFIInS, developed as part of the FISICA project under funding from the European Commission’s seventh Framework Programme for Research and Technological Development (FP7). Predicted results of wide field of view spatio–spectral interferometry through simulations of a long-baseline, double-Fourier, far-infrared interferometer concept are presented and analyzed. It is shown how such an interferometer, illuminated by a multimode detector can recover a large field of view at subarcsecond angular resolution, resulting in similar image quality as that achieved by illuminating the system with an array of coherent detectors. Through careful analysis, the importance of accounting for the correct number of higher-order optical modes is demonstrated, as well as accounting for both orthogonal polarizations. Given that it is very difficult to manufacture waveguide and feed structures at sub-mm wavelengths, the larger multimode design is recommended over the array of smaller single mode detectors. A brief note is provided in the conclusion of this paper addressing a more elegant solution to modeling far-infrared interferometers, which holds promise for improving the computational efficiency of the simulations presented here
Effectiveness and persistence of golimumab as a second biological drug in patients with spondyloarthritis
This observational, longitudinal retrospective, noncomparative study was designed to assess the persistence and effectiveness of golimumab as a second anti-tumor necrosis factor (TNF) drug in patients with spondyloarthritis requiring discontinuation from a first anti-TNF drug.Data were collected retrospectively for all patients with axial spondyloarthritis or psoriatic arthritis from 20 rheumatology clinics in Spain who started golimumab as a second anti-TNF drug between January 2013 and December 2015. Golimumab persistence was assessed with Kaplan-Meier survival analysis, and associated factors were assessed with Cox regression analysis.210 patients started golimumab as a second anti-TNF drug: 131 with axial spondyloarthritis and 79 with psoriatic arthritis. In axial spondyloarthritis patients, the mean (standard deviation) Bath Ankylosing Spondylitis Disease Activity Index score at baseline was 5.5 (2.1), decreasing to 3.9 (2.0) at month 3 and 3.5 (2.0) at year 1, and remaining stable thereafter. In psoriatic arthritis patients, mean (standard deviation) baseline Disease Activity Score was 4.0 (1.3), reducing to 2.5 (1.2) at month 3 and to 2.2 (1.3) at year 1. Corresponding improvements were recorded from baseline in C-reactive protein levels and erythrocyte sedimentation rates. The probability of persistence of treatment with golimumab was 80% at year 1, 70% at year 2 and 65% at years 3 and year 4, and was similar in those who had stopped the first anti-TNF due to loss of efficacy or other reasons. Cox regression analysis showed that the probability of survival with golimumab was higher in patients with higher erythrocyte sedimentation rate, in patients with axial spondyloarthritis than with psoriatic arthritis, and in those who had discontinued adalimumab as first anti-TNF. Seventy-two patients (34.3%) discontinued golimumab during follow-up, 50 of them due to lack of efficacy.In patients with spondyloarthritis requiring discontinuation from a first anti-TNF drug, treatment with golimumab was effective and showed a high probability of persistence up to 4 years of treatment
A Dispersive Backend Design for the 'Double-Fourier' Interferometer BETTII
BETTII (Balloon Experimental Twin Telescope for Infra-red Interferometry) is designed to provide high angular resolution spectroscopic data in the far-infrared (FIR) wavelengths. The most significant limitation for BETTII is its sensitivity; obtaining spectral signal-to-noise ratio greater than 5 in less than 10 minutes requires sources greater than 13 Janskys (Jy). One possible way to improve the signal-to-noise ratio (SNR) for future BETTII flights is by reducing the spectral bandwidth post beam-combination. This involves using a dispersive element to spread out a polychromatic point source PSF (Point Spread Function) on the detector array, such that each pixel corresponds to a small fraction of the bandwidth. This results in a broader envelope of the interferometric fringe pattern allowing more fringes to be detected, and thereby improving the spectral SNR. Here we present the analysis and optical design of the dispersive backend, discussing the tradeoffs and how it can be combined with the existing design
Quasi-optical analysis of a far-infrared spatio-spectral space interferometer concept
FISICA (Far-Infrared Space Interferometer Critical Assessment) was a three year study of a far-infrared spatio-spectral double-Fourier interferometer concept. One of the aims of the FISICA study was to set-out a baseline optical design for such a system, and to use a model of the system to simulate realistic telescope beams for use with an end-to-end instrument simulator. This paper describes a two-telescope (and hub) baseline optical design that fulfils the requirements of the FISICA science case, while minimising the optical mass of the system. A number of different modelling techniques were required for the analysis: fast approximate simulation tools such as ray tracing and Gaussian beam methods were employed for initial analysis, with GRASP physical optics used for higher accuracy in the final analysis. Results are shown for the predicted far-field patterns of the telescope primary mirrors under illumination by smooth walled rectangular feed horns. Far-field patterns for both on-axis and off-axis detectors are presented and discussed
Adaptive optics performance of a simulated coronagraph instrument on a large, segmented space telescope in steady state
Directly imaging Earth-like exoplanets (``exoEarths'') with a coronagraph
instrument on a space telescope requires a stable wavefront with optical path
differences limited to tens of picometers RMS during exposure times of a few
hours. While the structural dynamics of a segmented mirror can be directly
stabilized with telescope metrology, another possibility is to use a
closed-loop wavefront sensing and control system in the coronagraph instrument
that operates during the science exposures to actively correct the wavefront
and relax the constraints on the stability of the telescope. In this paper, we
present simulations of the temporal filtering provided using the example of
LUVOIR-A, a 15~m segmented telescope concept. Assuming steady-state aberrations
based on a finite element model of the telescope structure, we (1)~optimize the
system to minimize the wavefront residuals, (2)~ use an end-to-end numerical
propagation model to estimate the residual starlight intensity at the science
detector, and (3)~predict the number of exoEarth candidates detected during the
mission. We show that telescope dynamic errors of 100~pm~RMS can be reduced
down to 30~pm~RMS with a magnitude 0 star, improving the contrast performance
by a factor of 15. In scenarios where vibration frequencies are too fast for a
system that uses natural guide stars, laser sources can increase the flux at
the wavefront sensor to increase the servo-loop frequency and mitigate the high
temporal frequency wavefront errors. For example, an external laser with an
effective magnitude of -4 allows the wavefront from a telescope with 100~pm~RMS
dynamic errors and strong vibrations as fast as 16~Hz to be stabilized with
residual errors of 10~pm~RMS thereby increasing the number of detected planets
by at least a factor of 4.Comment: Published in JATIS. arXiv admin note: substantial text overlap with
arXiv:2108.0640
Optical and Quasi-Optical Analysis of System Components for a Far-Infrared Space Interferometer
Many important astrophysical processes occur at wavelengths that fall within the far-infrared band of the EM spectrum, and over distance scales that require sub-arc second spatial resolution. It is clear that in order to achieve sub-arc second resolution at these relatively long wavelengths (compared to optical/near-IR), which are strongly absorbed by the atmosphere, a space-based far-IR interferometer will be required. We present analysis of the optical system for a proposed spatial-spectral interferometer, discussing the challenges that arise when designing such a system and the simulation techniques employed that aim to resolve these issues. Many of these specific challenges relate to combining the beams from multiple telescopes where the wavelengths involved are relatively short (compared to radio interferometry), meaning that care must be taken with mirror surface quality, where surface form errors not only present potential degradation of the single system beams, but also serve to reduce fringe visibility when multiple telescope beams are combined. Also, the long baselines required for sub-arc second resolution present challenges when considering propagation of the relatively long wavelengths of the signal beam, where beam divergence becomes significant if the beam demagnification of the telescopes is not carefully considered. Furthermore, detection of the extremely weak far-IR signals demands ultra-sensitive detectors and instruments capable of operating at maximum efficiency. Thus, as will be shown, care must be taken when designing each component of such a complex quasioptical system
The Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII): towards the first flight
The Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII) is a balloon-borne, far-infrared
direct detection interferometer with a baseline of 8 m and two collectors of 50 cm. It is designed to study
galactic clustered star formation by providing spatially-resolved spectroscopy of nearby star clusters. It is being
assembled and tested at NASA Goddard Space Flight Center for a first flight in Fall 2016. We report on recent
progress concerning the pointing control system and discuss the overall status of the project as it gets ready forits commissioning flight
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