Chapter 19- I See Research Questions Everywhere : Developing Metacognitive Skills in an English-Major Research Methods Course

How many ways can sticky notes—branded as Post-it Notes and introduced in 1980 by 3M—be used by college students? According to the undergraduate who investigated this topic, 31. In the report she produced as a result of a study conducted in English 3470: Approaches to Research in English Studies, the researcher found that “many stationery products have died with advancements in technology, but the Post-it Note has thrived and continues to play a role in productivity in the workplace, continuing at the top of the supply list” (Eralie, 2019). To come to this magic number of 31, Megan conducted a case study and used tools such as a Qualtrics survey. She shared the results with the campus community through a poster during the annual Student Research Symposium (Eralie, 2019). Megan did not arrive in class thinking, “Oh, I’m going to focus on uses of sticky notes for my project”; the topic came to the forefront when I noticed that Megan had what I thought was an atypical way to store information from class lectures—on sticky notes, which could then be organized and re-organized easily, as she pointed out to me. This was an analog strategy for a digital native

Job Demands of Occupational Therapy Clinical Placements: A Descriptive Study Using the Practicum Demands Measure©

The purpose of this study was to group and analyze the Practicum Demands Measure© (PDM) data collected over 2 academic years and create a general profile of demands across practicum settings. The data will be used to guide faculty in the most suitable placement of students requiring accommodations for a disability. The study used a secondary analysis design to analyze the 538 participant PDM data collected over the 2017/2018 and 2018/2019 academic years. Most of the sampled students were in fieldwork Level I and worked in mental health settings. The students reported physical demands, such as lifting more than 5kg (65.7%), intermittent sitting (97.6%), and keyboarding (94.6%). They also reported physical environment characteristics, such as exposure to infectious disease (44.6%) and congested working areas (27.5%). Cognitive demands included instant recall (90%) and analytical and clinical reasoning (99.8%). Practicum demands in occupational therapy were similar across other health care profession student placements, such as nursing and physical therapy. Practicum demands need to be studied more extensively to optimize students’ opportunities for success for students requiring accommodations in varied clinical settings

Impact of child nutrition programs offered in schools on daily nutrition and dietary quality

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

LTE1 promotes exit from mitosis by multiple mechanisms

In budding yeast, alignment of the anaphase spindle along the mother–bud axis is crucial for maintaining genome integrity. If the anaphase spindle becomes misaligned in the mother cell compartment, cells arrest in anaphase because the mitotic exit network (MEN), an essential Ras-like GTPase signaling cascade, is inhibited by the spindle position checkpoint (SPoC). Distinct localization patterns of MEN and SPoC components mediate MEN inhibition. Most components of the MEN localize to spindle pole bodies. If the spindle becomes mispositioned in the mother cell compartment, cells arrest in anaphase due to inhibition of the MEN by the mother cell–restricted SPoC kinase Kin4. Here we show that a bud-localized activating signal is necessary for full MEN activation. We identify Lte1 as this signal and show that Lte1 activates the MEN in at least two ways. It inhibits small amounts of Kin4 that are present in the bud via its central domain. An additional MEN-activating function of Lte1 is mediated by its N- and C-terminal GEF domains, which, we propose, directly activate the MEN GTPase Tem1. We conclude that control of the MEN by spindle position is exerted by both negative and positive regulatory elements that control the pathway’s GTPase activity.National Institutes of Health (U.S.) (Grant HD085866)National Cancer Institute (U.S.)David H. Koch Institute for Integrative Cancer Research at MIT. Support (Core) (Grant P30-CA14051

Collaboration between Librarians and Learning Technologists to enhance the learning of health sciences students.

Collaboration between Librarians and Learning Technologists at Bournemouth University (BU) has been stimulated and cemented by Pathfinder funding from the Higher Education Academy. This paper will consider four case studies collected as part of the eRes Project that describe the use of Web 2.0 technologies in the School of Health and Social Care at BU. The project aimed to enhance the student learning experience in an increasingly electronic environment. This was achieved by developing and disseminating innovative pedagogical frameworks, bringing together learning activities and academically led quality e-resources within the unit of study. An e-reading strategy which encompasses models for resource discovery and e-literacy was developed, drawing on the experiences and findings of the case studies. Issues considered in this paper will include accessing academic electronic reading materials and using a social bookmarking tool integrated within BU’s virtual learning environment with students studying away from the main campus. Additionally the paper will consider how technology can be used to motivate students, especially in large groups and how it can be used to engage students with a subject perceived as “dry” or “difficult”. The rich possibilities of health science materials can be exploited more fully using new technologies embedded within the curriculum

Hydration and athletes

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Unfitness to Plead. Volume 1: Report.

This has been produced along with Volume 2: Draft Legislation as a combined document Presented to Parliament pursuant to section 3(2) of the Law Commissions Act 1965 Ordered by the House of Commons to be printed on 12 January 201

Application of functional genomics to the chimeric mouse model of HCV infection: optimization of microarray protocols and genomics analysis

BACKGROUND: Many model systems of human viral disease involve human-mouse chimeric tissue. One such system is the recently developed SCID-beige/Alb-uPA mouse model of hepatitis C virus (HCV) infection which involves a human-mouse chimeric liver. The use of functional genomics to study HCV infection in these chimeric tissues is complicated by the potential cross-hybridization of mouse mRNA on human oligonucleotide microarrays. To identify genes affected by mouse liver mRNA hybridization, mRNA from identical human liver samples labeled with either Cy3 or Cy5 was compared in the presence and absence of known amounts of mouse liver mRNA labeled in only one dye. RESULTS: The results indicate that hybridization of mouse mRNA to the corresponding human gene probe on Agilent Human 22 K oligonucleotide microarray does occur. The number of genes affected by such cross-hybridization was subsequently reduced to approximately 300 genes both by increasing the hybridization temperature and using liver samples which contain at least 80% human tissue. In addition, Real Time quantitative RT-PCR using human specific probes was shown to be a valid method to verify the expression level in human cells of known cross-hybridizing genes. CONCLUSION: The identification of genes affected by cross-hybridization of mouse liver RNA on human oligonucleotide microarrays makes it feasible to use functional genomics approaches to study the chimeric SCID-beige/Alb-uPA mouse model of HCV infection. This approach used to study cross-species hybridization on oligonucleotide microarrays can be adapted to other chimeric systems of viral disease to facilitate selective analysis of human gene expression

Coregulated human globin genes are frequently in spatial proximity when active

The organization of genes within the nucleus may influence transcription. We have analyzed the nuclear positioning of the coordinately regulated α- and β-globin genes and show that the gene-dense chromatin surrounding the human α-globin genes is frequently decondensed, independent of transcription. Against this background, we show the frequent juxtaposition of active α- and β-globin genes and of homologous α-globin loci that occurs at nuclear speckles and correlates with transcription. However, we did not see increased colocalization of signals, which would be expected with direct physical interaction. The same degree of proximity does not occur between human β-globin genes or between murine globin genes, which are more constrained to their chromosome territories. Our findings suggest that the distribution of globin genes within erythroblast nuclei is the result of a self-organizing process, involving transcriptional status, diffusional ability of chromatin, and physical interactions with nuclear proteins, rather than a directed form of higher-order control