The Effects of Super-dosing Phytase on Nursery and Grower Pigs

To determine the effects of super-dosing on pigs fed phosphorous and calcium adequate or deficient diets (Experiment 1); the optimum level of corn express phytase (CEP, Experiment 2); and the effects of xylanase/phytase on growth performance (Experiment 3) in pigs fed reduce nutrient diets, weaned pigs were blocked with initial body weight (BW) and allotted to dietary treatments. Treatments were: Positive control (PC), P/Ca adequate diets (NRC 2012); Negative Control (NC), low P (-0.15%) and Ca (-0.12%), +0, 1000, and 4000 FTU/kg of CEP in both PC and NC (Experiment 1); PC, P/Ca adequate diets; NC, decreased P (0.15%) and Ca (0.1%),+ 500, 1000, and 1500 FTU/kg CEP or NC+500 FTU/kg of Hiphos GT (Experiment 2); PC, P/Ca adequate diet (+500 FTU/kg of phytase); NC, reduced ME and AA of feed; NC+15,000 FTU/kg of phytase, +0, 12,000 or 16,000 DXU/kg of xylanase (Experiment 3). Data were analyzed by MIXED procedures of SAS (SAS inst., Cary, NC) with treatments as fixed effect and initial BW as random effect. In Exp. 1, ADG (P \u3c 0.05) and BW (P \u3c 0.05) were linearly increased with increasing level of CEP in pigs fed NC diets, but not in those fed PC diets (CEP x P/Ca-level interaction). CEP supplementation improved percentage bone ash (P \u3c 0.05) quadratically, independent of P/Ca levels. For Exp. 2, increasing CEP increased ADG (P\u3c0.01), G:F (P \u3c 0.05), and BW (P \u3c 0.05) linearly, and added both phytase at 500 FTU/kg (CEP and HiPhos) restored growth performance phenotypes to PC diets. In Exp. 3, adding the combination of 16,000 DXU/kg xylanase and super-dosing phytase restored BW (P \u3e 0.10) similar to the PC when pigs fed reduced ME and AA diets. Pigs fed diets supplement with 16,000 DXU/kg xylanase or super-dosing phytase alone had similar G:F to the PC fed pigs. In addition, pigs fed 16,000 DXU/kg of xylanase diet had similar carcass composition compared to the NC (P \u3e 0.10). These experiments suggest phytase in nutrient deficient diets restores growth performance similar to pigs fed an adequate diet, and corn expressed phytase is as effective as microbial phytase in pigs

Parameter counting in models with global symmetries

We present rules for determining the number of physical parameters in models with exact flavor symmetries. In such models the total number of parameters (physical and unphysical) needed to described a matrix is less than in a model without the symmetries. Several toy examples are studied in order to demonstrate the rules. The use of global symmetries in studying the minimally supersymmetric standard model (MSSM) is examined.Comment: 16 page

Automated in-row weed trimmer

The Automated In-Row Weed Trimmer, or AIRWT, is a weed removal system designed to be used in vineyards in order to enable safe and e cient removal of weeds while preventing damage to the vines. The goal of the system is to reduce the need for the use of manual labor and herbicides while improving production rates of grapes by automating the weed removal process at vineyards. By implementing an automated system for weed removal, the team aims to resolve ethical issues in food production, primarily those surrounding human labor, environmental friendliness, and social sustainability. The focus of this report is to explore in depth the AIRWT system concept as well as its subsystems, in addition to reviewing its product development cycle

Framework for Classifying Compliance and Medical Immediacy among Low-Acuity Presentations at an Urban Trauma Center

Background: This research offers two exploratory frameworks for medical regimen compliance and medical immediacy. The first classifies compliance awareness, compliance mitigation, and financial limitation for those patients that exhibit nonadherence with a medical regimen. The second classifies medical immediacy and characterizes avoidable utilization. Methods: Representative sampling of adult patients presenting at an emergency department (62,000/ppy) triaged as low acuity; emergency department physician assessment of noncompliance with medical regimen for those patients with a complaint related to a chronic condition; and emergency department physician assessment of medical immediacy and avoidable utilization. Results: Physicians report 48.3% (95% confidence interval (CI) 43.5% to 53.1%) of patients with at least a single chronic condition are presenting with symptoms or complaint related a chronic condition, and 39.6% (CI 31.7% to 47.4%) of these exhibit noncompliance with the medical regimen associated with that chronic condition. 16.4% (CI 6.6% to 26.1%) of the patients exhibit pseudo compliance, a belief that the medical regimen is in compliance when in fact it is not. If the patient had been in compliance, 85.9% (CI 77.0% to 94.8%) of the presenting conditions may have been mitigated. Noncompliance cases (34.5% (CI 22.0% to 47.1%)) are partly attributable to financial constraints. Further, 19.1% (CI 15.7% to 22.5%) are assessed as requiring no medical intervention and 3.4% (CI 1.8% to 4.9%) require immediate stabilization. Conclusions: A large portion of low-acuity presentations are related to a chronic condition and noncompliance with the associated medical regimen contributes to the need to seek medical services. Interventions addressing literacy and financial constraints may increase compliance and decrease utilization

Decadal-scale shifts in soil hydraulic properties as induced by altered precipitation

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.Soil hydraulic properties influence the partitioning of rainfall into infiltration versus runoff, determine plant-available water, and constrain evapotranspiration. Although rapid changes in soil hydraulic properties from direct human disturbance are well documented, climate change may also induce such shifts on decadal time scales. Using soils from a 25-year precipitation manipulation experiment, we found that a 35% increase in water inputs substantially reduced infiltration rates and modestly increased water retention. We posit that these shifts were catalyzed by greater pore blockage by plant roots and reduced shrink-swell cycles. Given that precipitation regimes are expected to change at accelerating rates globally, shifts in soil structure could occur over broad regions more rapidly than expected and thus alter water storage and movement in numerous terrestrial ecosystems

Origin and evolution of the octoploid strawberry genome.

Cultivated strawberry emerged from the hybridization of two wild octoploid species, both descendants from the merger of four diploid progenitor species into a single nucleus more than 1 million years ago. Here we report a near-complete chromosome-scale assembly for cultivated octoploid strawberry (Fragaria × ananassa) and uncovered the origin and evolutionary processes that shaped this complex allopolyploid. We identified the extant relatives of each diploid progenitor species and provide support for the North American origin of octoploid strawberry. We examined the dynamics among the four subgenomes in octoploid strawberry and uncovered the presence of a single dominant subgenome with significantly greater gene content, gene expression abundance, and biased exchanges between homoeologous chromosomes, as compared with the other subgenomes. Pathway analysis showed that certain metabolomic and disease-resistance traits are largely controlled by the dominant subgenome. These findings and the reference genome should serve as a powerful platform for future evolutionary studies and enable molecular breeding in strawberry

Two More Candidate AM Canum Venaticorum (AM CVn) Binaries from the Sloan Digital Sky Survey

AM CVn systems are a select group of ultracompact binaries with the shortest orbital periods of any known binary subclass; mass-transfer is likely from a low-mass (partially-)degenerate secondary onto a white dwarf primary, driven by gravitational radiation. In the past few years, the Sloan Digital Sky Survey (SDSS) has provided five new AM CVns. Here we report on two further candidates selected from more recent SDSS data. SDSS J1208+3550 is similar to the earlier SDSS discoveries, recognized as an AM CVn via its distinctive spectrum which is dominated by helium emission. From the expanded SDSS Data Release 6 (DR6) spectroscopic area, we provide an updated surface density estimate for such AM CVns of order 10^{-3.1} to 10^{-2.5} per deg^2 for 15<g<20.5. In addition, we present another new candidate AM CVn, SDSS J2047+0008, that was discovered in the course of followup of SDSS-II supernova candidates. It shows nova-like outbursts in multi-epoch imaging data; in contrast to the other SDSS AM CVn discoveries, its (outburst) spectrum is dominated by helium absorption lines, reminiscent of KL Dra and 2003aw. The variability selection of SDSS J2047+0008 from the 300 deg^2 of SDSS Stripe 82 presages further AM CVn discoveries in future deep, multicolor, and time-domain surveys such as LSST. The new additions bring the total SDSS yield to seven AM CVns thus far, a substantial contribution to this rare subclass, versus the dozen previously known.Comment: 19 pages, 5 figures, 1 table; submitted to A

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

Despite their apparent lack of catalytic activity, pseudokinases are essential signaling molecules. Here, we describe the structural and dynamic properties of pseudokinase domains from the Wnt-binding receptor tyrosine kinases (PTK7, ROR1, ROR2, and RYK), which play important roles in development. We determined structures of all pseudokinase domains in this family and found that they share a conserved inactive conformation in their activation loop that resembles the autoinhibited insulin receptor kinase (IRK). They also have inaccessible ATP-binding pockets, occluded by aromatic residues that mimic a cofactor-bound state. Structural comparisons revealed significant domain plasticity and alternative interactions that substitute for absent conserved motifs. The pseudokinases also showed dynamic properties that were strikingly similar to those of IRK. Despite the inaccessible ATP site, screening identified ATP-competitive type-II inhibitors for ROR1. Our results set the stage for an emerging therapeutic modality of "conformational disruptors" to inhibit or modulate non-catalytic functions of pseudokinases deregulated in disease.Peer reviewe

Photometric Redshifts of Quasars

We demonstrate that the design of the Sloan Digital Sky Survey (SDSS) filter system and the quality of the SDSS imaging data are sufficient for determining accurate and precise photometric redshifts (``photo-z''s) of quasars. Using a sample of 2625 quasars, we show that photo-z determination is even possible for z<=2.2 despite the lack of a strong continuum break that robust photo-z techniques normally require. We find that, using our empirical method on our sample of objects known to be quasars, approximately 70% of the photometric redshifts are correct to within delta z = 0.2; the fraction of correct photometric redshifts is even better for z>3. The accuracy of quasar photometric redshifts does not appear to be dependent upon magnitude to nearly 21st magnitude in i'. Careful calibration of the color-redshift relation to 21st magnitude may allow for the discovery of on the order of 10^6 quasars candidates in addition to the 10^5 quasars that the SDSS will confirm spectroscopically. We discuss the efficient selection of quasar candidates from imaging data for use with the photometric redshift technique and the potential scientific uses of a large sample of quasar candidates with photometric redshifts.Comment: 29 pages, 8 figures, submitted to A