I Gotta Testify: Kanye West, Hip Hop, and the Church

The goal of this project, “I Gotta Testify: Kanye West, Hip Hop, and the Church,” is to add a new perspective to the scholarly discourse on Hip Hop and Christianity within classrooms, religious institutions, and popular culture by focusing on Kanye. We chose to focus on Kanye because he has been one of Hip Hop’s most influential artists in the past decade. Furthermore, Kanye is one of the most polarizing celebrities in America and across the globe. His music, fashion, political views, and family (which includes the Kardashians) dominate discourse on social media, blogs, television, and other forms of mass media. With the exception of Julius Bailey’s 2014 edited book, The Cultural Impact of Kanye West, there has been little scholarly work published on Kanye. Bailey’s book contained just one essay, written by Monica R. Miller, dedicated to the theme of Kanye and religion. We intended to produce a nontraditional journal issue, partly because Kanye has never adhered to traditional boundaries. We also chose this method because we wanted to provide a document suitable for both academic and popular audiences. Kanye West identifies as a Christian and primarily uses Christian themes in his music, videos, concerts, and messaging. Dr. Joshua K. Wright, Dr. Adria Y. Goldman and Dr. VaNatta S. For

Inferring evolutionary histories of pathway regulation from transcriptional profiling data

One of the outstanding challenges in comparative genomics is to interpret the evolutionary importance of regulatory variation between species. Rigorous molecular evolution-based methods to infer evidence for natural selection from expression data are at a premium in the field, and to date, phylogenetic approaches have not been well-suited to address the question in the small sets of taxa profiled in standard surveys of gene expression. We have developed a strategy to infer evolutionary histories from expression profiles by analyzing suites of genes of common function. In a manner conceptually similar to molecular evolution models in which the evolutionary rates of DNA sequence at multiple loci follow a gamma distribution, we modeled expression of the genes of an \emph{a priori}-defined pathway with rates drawn from an inverse gamma distribution. We then developed a fitting strategy to infer the parameters of this distribution from expression measurements, and to identify gene groups whose expression patterns were consistent with evolutionary constraint or rapid evolution in particular species. Simulations confirmed the power and accuracy of our inference method. As an experimental testbed for our approach, we generated and analyzed transcriptional profiles of four \emph{Saccharomyces} yeasts. The results revealed pathways with signatures of constrained and accelerated regulatory evolution in individual yeasts and across the phylogeny, highlighting the prevalence of pathway-level expression change during the divergence of yeast species. We anticipate that our pathway-based phylogenetic approach will be of broad utility in the search to understand the evolutionary relevance of regulatory change.Comment: 30 pages, 12 figures, 2 tables, contact authors for supplementary table

COMPLEX PULSE FORMING TEACHNIQUE USING AM DETECTOR TYPE CIRCUITRY AND THE APPLICATION OF CDMA TO RFID FOR THE SIMULTANEOUS READING OF MULTIPLE TAGS

A novel complex ultra wideband RF pulse forming technique has been implemented in this research, using the coefficients derived from discrete Fourier transform of a virtual pulse train. Incorporated in this technique is a multiple frequency communication systems designed such that transmitter receiver proximity and the fading effect of the individual frequencies make part of a corresponding modulation technique. A code division multiple access (CDMA) application to RFID to greatly reduce read time, while at the same time eliminating inter tag interference, has been investigated with the analysis of a typical cart aisle scenario. With the current rate of growth of inventory world wide there is a tremendous need for more efficient method of data gathering, data storage, and data retrieval. In this dissertation, the application of the CDMA RFID technology has been analyzed to demonstrate the potentials of integrating the RFID technology to the EPC global numbering system

Global Ionosonde and GPS Radio Occultation Sporadic-E Intensity and Height Comparison

A global, multi-year comparison of low and mid-latitude COSMIC GPS radio occultation (RO) sporadic-E (Es) plasma frequency and altitude and Digisonde blanketing frequency (fbEs) and altitude within 150 km and 30 minutes of each other. RO methods used to estimate the intensity of the Es layer include the scintillation index S4, total electron content (TEC) with both a constant and variable Es cloud thickness, and an Abel transform. The S4 and TEC with varying thickness techniques both under-represent the fbEs values while the TEC with constant thickness and Abel transform better estimate Digisonde fbEs values. All RO methods underestimate the altitude of the fbEs events as measured by the Digisondes. No method outperformed the other techniques across every metric, but the physical basis of the TEC technique provides an advantage over the empirically derived S4. The Abel transform also shows promise, but the lower resolution data currently available is detrimental to its performance. Overall, an automated TEC method tested on a larger data set could prove valuable for real-time global Es observation

The SYMBIOME Project: An Exploratory Investigation of the Biological, Psychological, and Social Mechanisms that Contribute to the Transition from Acute to Chronic Musculoskeletal Pain

This dissertation presents the initial findings of the SYMBIOME project; which attempts to combine the objective and subjective aspects of musculoskeletal pain to develop a prognostic clinical phenotype. Chapter 2 presents a moderator analysis of functional outcomes (pain interference and pain severity). Psychosocial moderators can affect the relationship between biomarkers and pain. For pain severity, TNF-α, TGF-β1, and CRP were moderated by employment status, pre-existing psychopathology, and sex. For pain interference, IL-1β, cortisol, TGF-β1, CRP, and IL-6 were moderated by pre-existing pain, peri-traumatic fear, region of injury, and peri-traumatic stress. Chapter 3 presents a latent growth curve analysis in determining the recovery trajectories of acute non-catastrophic musculoskeletal pain in the context of pain interference and severity over the course of 12 months. For pain interference, 3 distinct trajectories emerged: rapid recovery, delayed recovery, or minimal/no recovery. Pain severity favored a 2-trajectory model with rapid recovery or minimal/no recovery. Classification of recovery group depended on both baseline symptoms and relative rate of symptom decline. Recovery outcomes appeared to stabilize after a period of 3 months. Chapter 4 presents latent class analysis and growth mixture modeling as applied to a panel of 8 biomarkers (TNF-α, IL-1β, IL-6, CRP, IL-10, cortisol, BDNF, and TGF-β1). These markers may have the potential to discriminate between functional recovery outcomes. Using these markers, 3 meaningful groups or classes were identified. These groups could be adequately defined by using only 3 of the 8 markers (IL-1β, BDNF, and TGF-β1) where classes were organized by low concentration of markers in serum, average concentration, or high concentration of BDNF and TGF-β1. Those with high concentration of BDNF/TGF-β1 were more likely to score higher on self-report measures of pain and disability in their 6-month outcomes. These results support the claim that physiological factors are tied to pain through more than simple bivariate relationships. The context of the musculoskeletal trauma, both personal and social, can affect the behavior of biological systems

Foreign Currency for Long-Term Investors

Conventional wisdom holds that conservative investors should avoid exposure to foreign currency risk. Even if they hold foreign equities, they should hedge the currency exposure of these positions and should hold only domestic Treasury bills. This paper argues that the conventional wisdom may be wrong for long-term investors. Domestic bills are risky for long-term investors, because real interest rates vary over time and bills must be rolled over at uncertain future interest rates. This risk can be hedged by holding foreign currency if the domestic currency tends to depreciate when the domestic real interest rate falls, as implied by the theory of uncovered interest parity. Empirically this effect is important and can lead conservative long-term investors to hold more than half their wealth in foreign currency.