15 research outputs found
Opioid-Ketamine and Norketamine Codrug Combinations for Pain Management
Get PDFThe present invention relates to the field of pain management, and more particularly to synergistic codrugs comprising an opioid and ketamine or norketamine which have been combined to form a single chemical codrug entity. When the codrug is administered it produces a synergistic analgesic response to pain
Opioid-Nornicotine Codrugs Combinations for Pain Management
Get PDFThe present invention relates to the field of pain management, and more particularly to synergistic codrugs comprising an opioid and nornicotine which have been combined to form a single chemical codrug entity. When the codrug is administered it produces a synergistic analgesic response to pain
Use of \u3cem\u3eTris\u3c/em\u3e-Quaternary Ammonium Salts as Pain Modulating Agents
Get PDFProvided are tris-quatemary ammonium compounds which are modulators of nociception and pain
Bis-Quaternary Ammonium Salts as Pain Modulating Agents
Get PDFProvided are methods for using his-quaternary ammonium compounds to treat inflammatory pain, neuropathic pain and nociceptive pain
Methods for Treating Neuropathic Pain
Get PDFProvided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropathic pain and nociceptive pain
Novel Small Molecule α9α10 Nicotinic Receptor Antagonist Prevents and Reverses Chemotherapy-Evoked Neuropathic Pain in Rats
No full textThe novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic
No full textDiscovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain
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