Individualism versus collectivism in industrial relations

Over recent decades, the world economy has gone through radical changes in response to competitive pressures in globalising product and service markets. The removal of trade barriers has paved the way to a significant increase in international competitiveness, leading in turn to new employment relationships. There has been a proliferation of part-time work, temporary work, contract work and home working. Long, 'just-in-case' runs and inventories in the manufacturing sector are something of the past. And, as if this is not enough, breakthroughs in information technology have opened new horizons and ushered in new forms of employment relationships that are complex and diverse.peer-reviewe

Retreatment for hepatitis C virus direct-acting antiviral therapy virological failure in primary and tertiary settings: The REACH-C cohort

Virological failure occurs in a small proportion of people treated for hepatitis C virus (HCV) with direct-acting antiviral (DAA) therapies. This study assessed retreatment for virological failure in a large real-world cohort. REACH-C is an Australian observational study (n = 10,843) evaluating treatment outcomes of sequential DAA initiations across 33 health services between March 2016 to June 2019. Virological failure retreatment data were collected until October 2020. Of 408 people with virological failure (81% male; median age 53; 38% cirrhosis; 56% genotype 3), 213 (54%) were retreated once; 15 were retreated twice. A range of genotype specific and pangenotypic DAAs were used to retreat virological failure in primary (n = 56) and tertiary (n = 157) settings. Following sofosbuvir/velpatasvir/voxilaprevir availability in 2019, the proportion retreated in primary care increased from 21% to 40% and median time to retreatment initiation declined from 294 to 152 days. Per protocol (PP) sustained virological response (SVR12) was similar for people retreated in primary and tertiary settings (80% vs 81%; p = 1.000). In regression analysis, sofosbuvir/velpatasvir/voxilaprevir (vs. other regimens) significantly decreased likelihood of second virological failure (PP SVR12 88% vs. 77%; adjusted odds ratio [AOR] 0.29; 95%CI 0.11–0.81); cirrhosis increased likelihood (PP SVR12 69% vs. 91%; AOR 4.26; 95%CI 1.64–11.09). Indigenous Australians had lower likelihood of retreatment initiation (AOR 0.36; 95%CI 0.15–0.81). Treatment setting and prescriber type were not associated with retreatment initiation or outcome. Virological failure can be effectively retreated in primary care. Expanded access to simplified retreatment regimens through decentralized models may increase retreatment uptake and reduce HCV-related mortality

Paroles et images de l'immigration Langue, Littérature et Cinéma: témoins de la présence italienne au Luxembourg et dans la Grande Région Actes du colloque international Luxembourg 3-4 juin 2005

Les voyages, transits ou permanences, ont généré une grande richesse de sources historiques, littéraires, artistiques (y compris photographiques et cinématographiques). Et ce, plus précisément, concernant le Luxembourg et la Grande Région, où l'expérience de la grande vague de l'immigration italienne (à partir des années 1890) a non seulement comporté une transformation des paradigmes identitaires des nouveaux arrivants mais aussi du vécu des Luxembourgeois. L'art et la langue documentent l'impact parmi les cultures, ils ont la capacité extraordinaire de capturer les sentiments les plus subtils du phénoméne de la rencontre entre nouveaux arrivants et les autochtones