114 research outputs found
The role of thermal self-regulation in the biofeedback treatment of migraine headache : a controlled study
Le but de l'Ă©tude Ă©tait d'Ă©valuer le rĂŽle de PautorĂ©gulatlon de la tempĂ©rature dans le traitement de la migraine par la rĂ©troaction biologique thermique en la comparant Ă une procĂ©dure tout aussi crĂ©dible mais qui ne provoquerait aucun effet significatif sur la tempĂ©rature des mains. Vingt-quatre femmes migraineuses ont Ă©tĂ© assignĂ©es Ă l'une ou l'autre des deux conditions suivantes: la rĂ©troaction biologique thermique ou le TENS (ou stimulation Ă©lectrique transcutanĂ©e). Cette derniĂšre Ă©tait appliquĂ©e de façon Ă maximiser les attentes thĂ©rapeutiques et Ă minimiser les effets sur la tempĂ©rature des mains. La manipulation expĂ©rimentale s'est avĂ©rĂ©e un succĂšs. Cependant, aucune des diffĂ©rences observĂ©es entre les groupes au niveau des effets thĂ©rapeutiques n'Ă©tait significative. Il en est de mĂȘme des corrĂ©lations qui furent effectuĂ©es entre les changements de tempĂ©rature au niveau de la main et l'amĂ©lioration thĂ©rapeutique. Ainsi, l'hypothĂšse selon laquelle l'efficacitĂ© de la rĂ©troaction biologique serait mĂ©diĂ©e par l'autorĂ©gulation de la tempĂ©rature n'est pas supportĂ©e dans cette Ă©tude
Prevalence of insomnia and its treatment in Canada
Objectives : To estimate the prevalence of insomnia and examine its correlates (for example, demographics and physical and mental health) and treatments.
Methods : A sample of 2000 Canadians aged 18 years and older responded to a telephone survey about sleep, health, and the use of sleep-promoting products. Respondents with insomnia were identified using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, and the International Classification of Diseases, Tenth Edition, criteria.
Results : Among the sample, 40.2% presented at least 1 symptom of insomnia (that is, trouble falling or staying asleep, or early morning awakening) for a minimum of 3 nights per week in the previous month, 19.8% were dissatisfied with their sleep, and 13.4% met all criteria for insomnia (that is, presence of 1 insomnia symptom 3 nights or more per week for at least 1 month, accompanied by distress or daytime impairment). Insomnia was associated with female sex, older age, and poorer self-rated physical and mental health. Thirteen per cent of respondents had consulted a health care provider for sleep difficulties once in their lifetime. Moreover, 10% had used prescribed medications for sleep in the previous year, 9.0% used natural products, 5.7% used over-the-counter products, and 4.6% used alcohol. There were differences between French- and English-speaking adults, with the former group presenting lower rates of insomnia (9.5%, compared with 14.3%) and consultation (8.7%, compared with 14.4%), but higher rates of prescribed medications (12.9%, compared with 9.3%) and the use of natural products (15.6%, compared with 7.4%).
Conclusions : Insomnia is a prevalent condition, although few people seek professional consultation for this condition. Despite regional differences in the prevalence and treatments used to manage insomnia, prescribed medications remain the most widely used therapeutic option.Objectifs : Estimer la prévalence de l'insomnie et examiner ses corrélats (par exemple, les données démographiques et la santé physique et mentale) et les traitements.
MĂ©thodes : Un Ă©chantillon de 2000 Canadiens de 18 ans et plus ont rĂ©pondu Ă une enquĂȘte tĂ©lĂ©phonique sur le sommeil, la santĂ© et l'utilisation de produits qui favorisent le sommeil. Les rĂ©pondants souffrant d'insomnie ont Ă©tĂ© identifiĂ©s Ă l'aide des critĂšres du Manuel diagnostique et statistique des troubles mentaux, 4e Ă©dition rĂ©visĂ©e, et de la Classification internationale des maladies, 10e Ă©dition.
Résultats : Dans l'échantillon, 40,2 % présentaient au moins 1 symptÎme d'insomnie (c'est-à -dire, difficulté à s'endormir ou à rester endormi, ou réveil tÎt le matin) pour un minimum de 3 nuits par semaine durant le mois précédent, 19,8 % étaient insatisfaits de leur sommeil, et 13,4 % satisfaisaient à tous les critÚres de l'insomnie (c'est-à -dire, la présence d'un symptÎme d'insomnie 3 nuits ou plus par semaine pendant au moins 1 mois, accompagnée de détresse ou d'incapacité durant le jour). L'insomnie était associée avec le sexe féminin, l'ùge avancé, et une mauvaise santé physique et mentale auto-déclarée. Treize pour cent des répondants avaient consulté un prestataire de soins de santé pour des difficultés de sommeil une fois dans leur vie. En outre, 10 % avaient utilisé des médicaments prescrits pour le sommeil dans l'année précédente, 9,0 % avaient utilisé des produits naturels, 5,7 % avaient utilisé des produits en vente libre, et 4,6 % avaient utilisé de l'alcool. Il y avait des différences entre les adultes francophones et anglophones, le premier groupe présentant des taux plus faibles d'insomnie (9,5 %, comparé à 14,3 %) et de consultations (8,7 %, comparé à 14,4 %), mais des taux plus élevés de médicaments prescrits (12,9 %, comparé à 9,3 %) et d'utilisation de produits naturels (15,6 %, comparé à 7,4 %).
Conclusions : L'insomnie est une affection prévalente, bien que peu de gens aient recours à une consultation professionnelle pour ce problÚme. Malgré des différences régionales de prévalence et des traitements utilisés pour gérer l'insomnie, les médicaments prescrits demeurent l'option thérapeutique la plus utilisée
Insomnia and its relationship to health-care utilization, work absenteeism, productivity and accidents
Background and purpose
To document and provide a micro analysis of the relationship between insomnia and health problems, health-care use, absenteeism, productivity and accidents.
Participants and methods
A population-based sample of 953 French-speaking adults from Québec, Canada. Participants were categorized as having insomnia syndrome (SYND) or insomnia symptoms (SYMPT) or as good sleepers (GS). They completed questionnaires on sleep, health, use of health-care services and products, accidents, work absences and reduced work productivity. Data were also obtained from the Québec-government-administered health insurance board on selected variables (e.g., consultations with health-care professionals, diagnoses).
Results
There were significantly more individuals in the SYND group relative to the GS group reporting at least one chronic health problem (83% vs. 53%; OR: 2.78) and who had consulted a health-care professional in the past year (81% vs. 60%; OR: 2.8). There were also higher proportions of individuals in the SYND group than in the GS group who had used prescription medications (57% vs. 30.7%; OR: 2.8), most notably to treat insomnia, mood and anxiety disorders, or who had used over-the-counter products (75.6% vs. 62.0%; OR: 1.8) and alcohol as a sleep aid (17.8% vs. 3.9%; OR: 4.6). In terms of daytime function, 25.0% of the SYND had been absent from work relative to 17.1% of GS (OR: 1.7), 40.6% reported having experienced reduced productivity compared to 12.3% of GS (OR: 4.8) and non-motor-vehicle accidents occurred at higher rates in the SYND group (12.5% vs. 6.4% for GS; OR: 2.4). No differences were found for hospitalisations or motor-vehicle accidents. Most of the associations remained significant even after controlling for psychiatric comorbidity. Rates for the SYMPT group were situated between SYND and GS on all major dependent variables. Furthermore, insomnia and fatigue were perceived as contributing significantly to accidents, absences and decreased work productivity, regardless of insomnia status.
Conclusions
This study indicates that insomnia is associated with significant morbidity in terms of health problems and health-care utilization, work absenteeism and reduced productivity, and risk of non-motor-vehicle accidents. Future studies should evaluate whether treating insomnia can reverse this morbidity
Anxiety following mild traumatic brain injury
Purpose/Objective: The goals of the present study were (1) to document the prevalence of
anxiety-related disorders and anxiety symptoms at 4, 8, and 12 months post-injury in individuals
with mild traumatic brain injury (mTBI) while considering pre-injury history of anxiety disorders
and (2) to verify whether the presence of anxiety in the first months following mTBI was
associated with more symptoms present one year after the injury. Research Method/Design:
One hundred and twenty participants hospitalized after an accident and having sustained mTBI
were assessed at 4, 8, and 12 months post-accident with the Mini-International Neuropsychiatric
Interview, the Hospital Anxiety and Depression Scale and questionnaires assessing fatigue,
irritability, perceived stress, cognitive difficulties, depression, insomnia, and pain. Results: At 4
months, 23.8% of participants presented with at least one anxiety-related disorder compared to
15.2% at 8 months and 11.2% at 12 months. Overall, 32.5% presented with at least one anxiety
disorder over the first 12 months post-mTBI. Participants with a history of anxiety (20.5%) were
significantly more anxious following their accident. Individuals who were anxious 4 months after
the accident presented with more symptoms in different areas 12 months post-injury compared to
non-anxious individuals. Conclusions/Implications: The present results highlight that anxiety
should be evaluated and managed carefully as it appears to be a key factor in the persistence of
other mTBI-related symptom
Monthly fluctuations of insomnia symptoms in a population-based sample
Study Objectives:
To document the monthly changes in sleep/insomnia status over a 12-month period; to determine the optimal time intervals to reliably capture new incident cases and recurrent episodes of insomnia and the likelihood of its persistence over time.
Design:
Participants were 100 adults (mean age = 49.9 years; 66% women) randomly selected from a larger population-based sample enrolled in a longitudinal study of the natural history of insomnia. They completed 12 monthly telephone interviews assessing insomnia, use of sleep aids, stressful life events, and physical and mental health problems in the previous month. A total of 1,125 interviews of a potential 1,200 were completed. Based on data collected at each assessment, participants were classified into one of three subgroups: good sleepers, insomnia symptoms, and insomnia syndrome.
Results:
At baseline, 42 participants were classified as good sleepers, 34 met criteria for insomnia symptoms, and 24 for an insomnia syndrome. There were significant fluctuations of insomnia over time, with 66% of the participants changing sleep status at least once over the 12 monthly assessments (51.5% for good sleepers, 59.5% for insomnia syndrome, and 93.4% for insomnia symptoms). Changes of status were more frequent among individuals with insomnia symptoms at baseline (mean = 3.46, SD = 2.36) than among those initially classified as good sleepers (mean = 2.12, SD = 2.70). Among the subgroup with insomnia symptoms at baseline, 88.3% reported improved sleep (i.e., became good sleepers) at least once over the 12 monthly assessments compared to 27.7% whose sleep worsened (i.e., met criteria for an insomnia syndrome) during the same period. Among individuals classified as good sleepers at baseline, risks of developing insomnia symptoms and syndrome over the subsequent months were, respectively, 48.6% and 14.5%. Monthly assessment over an interval of 6 months was found most reliable to estimate incidence rates, while an interval of 3 months proved the most reliable for defining chronic insomnia.
Conclusions:
Monthly assessment of insomnia and sleep patterns revealed significant variability over the course of a 12-month period. These findings highlight the importance for future epidemiological studies of conducting repeated assessment at shorter than the typical yearly interval in order to reliably capture the natural course of insomnia over time
Cognitive behavioral therapy, singly and combined with medication, for persistent insomnia : a randomized controlled trial
Context: Cognitive behavioral therapy (CBT) and hypnotic medications are efficacious
for short-term treatment of insomnia, but few patients achieve complete remission
with any single treatment. It is unclear whether combined or maintenance therapies
would enhance outcome.
Objectives: To evaluate the added value of medication over CBT alone for acute treatment
of insomnia and the effects of maintenance therapies on long-term outcome.
Design, Setting, and Patients: Prospective, randomized controlled trial involving
2-stage therapy for 160 adults with persistent insomnia treated at a university hospital
sleep center in Canada between January 2002 and April 2005.
Interventions: Participants received CBT alone or CBT plus 10 mg/d (taken at bedtime)
ofzolpidemforaninitial6-weektherapy,followedbyextended6-monththerapy.Patients
initially treated with CBT attended monthly maintenance CBT for 6 months or received no
additional treatment and those initially treated with combined therapy (CBT plus 10 mg/d
of zolpidem) continued with CBT plus intermittent use of zolpidem or CBT only.
Main Outcome Measures: Sleep onset latency, time awake after sleep onset, total
sleep time, and sleep efficiency derived from daily diaries (primary outcomes); treatment
response and remission rates derived from the Insomnia Severity Index (secondary
outcomes).
Results: Cognitive behavioral therapy used singly or in combination with zolpidem
produced significant improvements in sleep latency, time awake after sleep onset, and
sleep efficiency during initial therapy (all P .001); a larger increase of sleep time was
obtained with the combined approach (P=.04). Both CBT alone and CBT plus zolpidem
produced similar rates of treatment responders (60% [45/75] vs 61% [45/74],
respectively; P=.84) and treatment remissions (39% [29/75] vs 44% [33/74], respectively;
P=.52) with the 6-week acute treatment, but combined therapy produced a
higher remission rate compared with CBT alone during the 6-month extended therapy
phase and the 6-month follow-up period (56% [43/74 and 32/59] vs 43% [34/75
and 28/68]; P=.05). The best long-term outcome was obtained with patients treated
with combined therapy initially, followed by CBT alone, as evidenced by higher remission
rates at the 6-month follow-up compared with patients who continued to take
zolpidem during extended therapy (68% [20/30] vs 42% [12/29]; P=.04).
Conclusion: In patients with persistent insomnia, the addition of medication to CBT
produced added benefits during acute therapy, but long-term outcome was optimized
when medication is discontinued during maintenance CBT
The natural history of insomnia : a population-based 3-year longitudinal study
Background Despite its high prevalence, little information is available about the natural history of insomnia. The extent to which episodes of insomnia will persist or remit over time is difficult to predict. We examined the natural history of insomnia and describe the most common trajectories over 3 years.
Methods Three hundred eighty-eight adults (mean [SD] age, 44.8 [13.9] years; 61% women) were selected from a larger population-based sample on the basis of the presence of insomnia at baseline. They completed standardized sleep/insomnia questionnaires at 3 annual follow-up assessments. For each follow-up assessment, participants were classified into 1 of 3 groups (individuals with an insomnia syndrome, individuals with insomnia symptoms, and individuals with good sleep) on the basis of algorithms using standard diagnostic criteria for insomnia. Rates of persistent insomnia, remission, and relapse were computed for each group.
Results Of the study sample, 74% reported insomnia for at least 1 year (2 consecutive assessments) and 46% reported insomnia persisting over the entire 3-year study. The course of insomnia was more likely to be persistent in those with more severe insomnia at baseline (ie, insomnia syndrome) and in women and older adults. Remission rate was 54%; however, 27% of those with remission of insomnia eventually experienced relapse. Individuals with subsyndromal insomnia at baseline were 3 times more likely to remit than worsen to syndrome status, although persistence was the most frequent course in that group as well.
Conclusion These findings indicate that insomnia is often a persistent condition, in particular when it reaches the diagnostic threshold for an insomnia disorder
What is the prevalence of fear of cancer recurrence in cancer survivors and patients? A systematic review and individual participant data meta-analysis
This study was supported by the Dutch Cancer Society (KWF) grant number 10936.Objective Care for fear of cancer recurrence (FCR) is considered the most common unmet need among cancer survivors. Yet the prevalence of FCR and predisposing factors remain inconclusive. To support targeted care, we provide a comprehensive overview of the prevalence and severity of FCR among cancer survivors and patients, as measured using the short form of the validated Fear of Cancer Recurrence Inventory (FCRI-SF). We also report on associations between FCR and clinical and demographic characteristics. Methods This is a systematic review and individual participant data (IPD) meta-analysis on the prevalence of FCR. In the review, we included all studies that used the FCRI-SF with adult (â„18Â years) cancer survivors and patients. Date of search: 7 February 2020. Risk of bias was assessed using the Joanna Briggs Institute critical appraisal tool. Results IPD were requested from 87 unique studies and provided for 46 studies comprising 11,226 participants from 13 countries. 9311 respondents were included for the main analyses. On the FCRI-SF (range 0â36), 58.8% of respondents scored â„13, 45.1% scored â„16 and 19.2% scored â„22. FCR decreased with age and women reported more FCR than men. FCR was found across cancer types and continents and for all time periods since cancer diagnosis. Conclusions FCR affects a considerable number of cancer survivors and patients. It is therefore important that healthcare providers discuss this issue with their patients and provide treatment when needed. Further research is needed to investigate how best to prevent and treat FCR and to identify other factors associated with FCR. The protocol was prospectively registered (PROSPERO CRD42020142185).Publisher PDFPeer reviewe
Moderators of the effect of psychosocial interventions on fatigue in women with breast cancer and men with prostate cancer:Individual patient data meta-analyses
Objective Psychosocial interventions can reduce cancer-related fatigue effectively. However, it is still unclear if intervention effects differ across subgroups of patients. These meta-analyses aimed at evaluating moderator effects of (a) sociodemographic characteristics, (b) clinical characteristics, (c) baseline levels of fatigue and other symptoms, and (d) intervention-related characteristics on the effect of psychosocial interventions on cancer-related fatigue in patients with non-metastatic breast and prostate cancer. Methods Data were retrieved from the Predicting OptimaL cAncer RehabIlitation and Supportive care (POLARIS) consortium. Potential moderators were studied with meta-analyses of pooled individual patient data from 14 randomized controlled trials through linear mixed-effects models with interaction tests. The analyses were conducted separately in patients with breast (n = 1091) and prostate cancer (n = 1008). Results Statistically significant, small overall effects of psychosocial interventions on fatigue were found (breast cancer: beta = -0.19 [95% confidence interval (95%CI) = -0.30; -0.08]; prostate cancer: beta = -0.11 [95%CI = -0.21; -0.00]). In both patient groups, intervention effects did not differ significantly by sociodemographic or clinical characteristics, nor by baseline levels of fatigue or pain. For intervention-related moderators (only tested among women with breast cancer), statistically significant larger effects were found for cognitive behavioral therapy as intervention strategy (beta = -0.27 [95%CI = -0.40; -0.15]), fatigue-specific interventions (beta = -0.48 [95%CI = -0.79; -0.18]), and interventions that only targeted patients with clinically relevant fatigue (beta = -0.85 [95%CI = -1.40; -0.30]). Conclusions Our findings did not provide evidence that any selected demographic or clinical characteristic, or baseline levels of fatigue or pain, moderated effects of psychosocial interventions on fatigue. A specific focus on decreasing fatigue seems beneficial for patients with breast cancer with clinically relevant fatigue
- âŠ