9 research outputs found
Differential expression of NGF and BDNF in rat adipose depots during early development and adulthood
According to the current paradigm, the white adipose tissue (WAT) not only releases fatty acids, cholesterol, retinoids and other lipids stored in the adipocytes, but also produce and secrete numerous signaling proteins collectively termed adipokines. Among them are various cell growth factors such as nerve growth factor (NGF) and brain-derived growth factor (BDNF). While literature around obesity and its related diseases is abundant, we still do not know how WAT behaves during normal development. In the present study, we explored the expression of NGF and BDNF in the peripancreatic fat tissue (Ppf) and the epididymal fat tissue (Epf ) during a critical period for the metabolic maturation of male Wistar rats. At birth almost no abdominal WAT was observed in the rats. From day 15 to adulthood (2 months), it increased in weight. However, the adipocyte diameter was not different during the first month, compared to adulthood, indicating that the tissue growth in this stage was mostly hypertrophic, while in the second month we also observed hyperplasia of the adipocytes. We measured the production of the neutrophins NGF and BDNF by the abdominal WAT depots. We observed a significant reduction in the expression of NGF in Epf at 28d and two months. However, NGF expression in Ppf remained stable from postnatal 15d to adulthood, except for a nadir at 28d. On the other hand, we failed to detect BDNF during the first 2 months of life in Ppf, but it was expressed at detectable amounts in Epf, peaking at day 20. We do not know how these secretory changes influence the development of the cells and the surrounding tissues. However, in obesity the amount of WAT is increased, and it is necessary to understand the mechanisms of WAT growth in physiological state to identify with the unbalance in this tissue present in obesity.Adipobiology 2013; 5: 39-43
Corrigendum: Cellular scaling rules for the brain of Artiodactyla include a highly folded cortex with few neurons
Panorámica De La Cultura Ambiental En La Universidad Autónoma De Zacatecas. México. 2006-2016
La Universidad Autónoma de Zacatecas, desde su fundación y hasta el momento actual ha estado comprometida con la sociedad y el medio ambiente. En el año de 2006 presentó su proyecto de Cultura Ambiental ante CECADESU-SEMARNAT y ANUIES, este proyecto es transversal a todas las actividades sustantivas y adjetivas de la institución, acorde con su modelo académico UAZ siglo XXI.
Del año 2006-2012 se trabajó en Gestión Ambiental: Manejo y cuidado del agua y energÃa, procesos de forestación, espacios 100% libres de humo de tabaco, manejo de residuos no peligrosos y peligrosos, no uso de unicel. De 2009-2016 se inició el trabajo de Ambientalización de las Curriculas, acompañando estos procesos con formación en Cultura Ambiental de alumnos, profesores y trabajadores a través de conferencias, talleres, un diplomado y retroalimentando en investigación la realización de 4 simposios internacionales y 5 congresos internacionales. La UAZ forma parte de la RED de planes institucionales de Cultura Ambiental. Organizados por CECADESU-SEMARNAT-ANUIES.
Palabras clave: Cultura-Ambiental, Universidad Autónoma de Zacatecas
Generación de la huella ecológica en el personal de los 3 sectores de la población de la UAO/UAZ, Zacatecas, México
Es importante reconocer que lo que se realiza a diario en el área de trabajo, tiene una relación muy estrecha con la huella ecológica. Un problema grave es el desperdicio de agua y energÃa eléctrica, cuando a veces no es necesario en el trabajo, ya que son esencial para poder desempeñar las actividades, por eso se necesita tomar conciencia de esto y usar los servicios de luz y agua solo cuando se requiera. El objetivo de este trabajo es determinar la huella ecológica del personal de los tres sectores de la población de la Unidad Académica de OdontologÃa UAZ. La presente investigación consistió en: Aplicación de encuestas personales al sector alumnos, docentes y trabajadores. Resultados: Respecto al transporte público se determinó que el sector trabajador y alumnos son los que más lo utilizan. En la alimentación un 55% del sector alumnos consume alimentos en su hogar, el 50% del sector docente lo hace en la cafeterÃa escolar y el 48% del sector trabajador en casa. Referente a si se encuentra prendida la luz al inicio de las actividades, los tres sectores mencionan que sà en un gran porcentaje; asà mismo un uso inadecuado del agua. Se sugiere dentro de lo posible, usar el transporte público y usar el vehÃculo lo indispensable o colectivamente. Se propone optimizar el uso de equipo y aparatos que requieran consumo de energÃa, se recomienda utilizar lámparas ahorradoras de energÃa tipo LED. Siendo indispensable adquirir los conocimientos adecuados sobre la gestión de los RPBI de acuerdo con la NOM-O87ECOL-SSA1-2002.
El riego de los jardines por las mañanas y tardes. De la misma forma el agua utilizada en lavabos y depósitos de baños, se sustituya por agua reciclada por medio de sistemas de ahorro.
Palabras clave: Generación, huella-ecológica, población, UAO/UAZ.It is important to recognize that what we daily do in our jobs, has a very tight relationship with the ecological footprint. A serious problem is that we are wasting water and electricity, when sometimes it’s not necessary in our working areas, both elements water and electricity are essential to do our daily duties, that is why we need to create awareness and use these utilities only when are required. The objective of this study is to assess the ecological footprint from the three sectors of population from the academic unit of Dentistry UAZ. This research consisted in: Personal surveys applied to the sector of students, professors and staff. Results: in regards to the use of public transportation, it was concluded that staff and students are those who use it the most. With regards to nutrition, 55% of the students eat at home, 50% of the professors do it at the coffee shop of the university and 48% of the staff eats at home. With reference to whether if the lights are turned on at the moment of starting the academic activities, the three sectors agreed with it in a high proportion; also, the three sectors state that doesn’t exists an efficient use of water. It is suggested if possible, to use the public transport and the car only if necessary or travel in groups instead. It is proposed to use only if is absolutely necessary, all the equipment and devices that require a lot of electric energy consumption and it is recommended to use LED type energy efficient lamps. It is also suggested to acquire the proper knowledge about the RPBI (biological/infectious hazardous waste), in accordance with the NOM-O87ECOL-SSA1-2002. It is advisable to water gardens only in the morning, from 7 a.m. to 9 a.m., or in the afternoon, from 6 p.m. to 8 p.m. Similarly for the water used in the sink and the toilet deposit, it is proposed to use recycled water with saving systems instead.
Key Words: Generation, ecological-footprint, population, UAO/UAZ.
 
Espacios 100% libres de humo de tabaco en la UAZ, como prevención de la Epidemia del Tabaquismo
Introducción: La epidemia mundial del tabaquismo mata cada año a casi 6 millones de personas, de las cuales más de 600 000 son no fumadores que mueren por respirar humo ajeno. Si no actuamos, la epidemia matará a más de 8 millones de personas al año de aquà a 2030. Más del 80% de esas muertes evitables se producirán entre las poblaciones de los paÃses de ingresos bajos y medianos (Organización Mundial de la Salud 2014). De ahà la importancia de promover espacios 100% libres de humo detabaco, esta acción entre los jóvenes que son la población susceptible. En la UAZ con la implementación del Modelo académico UAZ Siglo XXI, contempla la formación integral de nuestros alumnos que conlleva a un desarrollo sostenible que sea para toda la vida.Objetivo: Implementar en todos los espacios Universitarios, espacios 100 % libres de humo de tabaco.Material y Métodos: El proceso se llevó en 2 etapas: (2007-2010), (2011-2013). Participando todos los sectores que conforman la UAZ, alumnos, docentes, trabajadores, autoridades administrativas. Procedimiento: 1.-Solicitud a la SecretarÃa de Salud, 2.- Que realizó cinco visitas, 3.-Que la Comunidad estuviera enterada del proceso, 4.-Colocación de ceniceros a la entrada del edificio, 5.-Señalamientos de espacio 100% libre de Humo de Tabaco, 6.-Señalamiento del Reglamento de la UAZ como espacio 100% libre de Humo de Tabaco.Resultados: La primera Etapa, se certificó el área de Ciencias de la Salud y CECIUAZ. En la segunda etapa se certificó 45 espacios de la UAZ.Conclusiones: Con este reconocimiento inicia el trabajo de retroalimentación y forma parte de la formación integral de nuestros alumnos, y del personal docente, trabajadores y administración central. Se programa una evaluación del programa en dos años
Corrigendum: Cellular scaling rules for the brain of Artiodactyla include a highly folded cortex with few neurons
EVALUATION OF TWO in vitro MATURATION MEDIUM FOR EMBRYO PRODUCTION IN SHEEP
The aim of this work was to evaluate the effect of HECM-9 and TCM-199 as maturation media on maturation (MR), in vitro fertilization (IVF) and embryo development (ED) rate of oocytes from hair sheep collected from slaughter house ovaries. Cumulus-oocyte-complexes (COC) were obtained by manual aspiration, from 2-6mm diameter follicles. Groups of 10-20 COC, quality 1 and 2 were placed into 450μL of HECM-9 or TCM-199 and incubated 24h at 38.5 ºC and 5% CO2. For IVF, COC were transferred to 450μL of SOFm+Oaa, 0.5 x 106 motile spermatozoa were added and then incubated at 38.5 ºC and 5% CO2. Alleged zygotes were transferred to 450μL of SOFm+Oaa+glucose. Embryo development and morphology were evaluated at 2, 4, 5 and 6 days of culture, not developed zygotes were removed on day 2 and the final rate of embryo production was determined on day 8 of culture. Oocyte MR showed no significant differences (P>0.05) between treatments (73.3 vs. 71.4 % HECM-9 and TCM-199, respectively). Fertilization rate was different (
Immunogenicity of 60 novel latency-related antigens of Mycobacterium tuberculosis
The aim of our work here was to evaluate the immunogenicity of 60 mycobacterial antigens, some of which have not been previously assessed, notably a novel series of in vivo-expressed M.tuberculosis (IVE-TB) antigens. We enrolled 505 subjects and separated them in individuals with and without latent tuberculosis infection (LTBI) versus patients with active tuberculosis. Following an overnight and 7 day stimulation of whole blood with purified recombinant M.tb antigens, interferon-γ (IFN-γ) levels were determined by ELISA. Several antigens could statistically significantly differentiate the groups of individuals. We obtained promising antigens from all studied antigen groups (DosR regulon encoded antigens; resuscitation-promoting factors (Rpf) antigens; IVE-TB antigens; reactivation asociated antigens). Rv1733, which is a probable conserved transmembrane protein encoded in DosR regulon, turned out to be very immunogenic and able to discriminate between the three defined TB status, thus considered a candidate biomarker. Rv2389 and Rv2435n, belonging to Rpf family and IVE-TB group of antigens, respectively, also stood out as LTBI biomarkers. Although more studies are needed to support our findings, the combined use of these antigens would be an interesting approach to tuberculosis immunodiagnosis candidates