7 research outputs found

    Le masque comme processus ironique. Les makishi du nord-ouest de la Zambie

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    Le masque comme processus ironique Les makishi du nord-ouest de la ZambieL'utilisation des masques dans les cérémonies d'initiation des populations du nord-ouest de la Zambie est traditionnelle et chargée de messages symboliques mythiques et sociaux. Cet article vise à illustrer l'utilisation et les rôles des masques dans les contextes politiques postcoloniaux actuels au nord-ouest de la Zambie. Les masques traditionnels servent de lieu où penser et s'approprier les réalités nouvelles que les populations affrontent à travers l'humour et l'ironie des personnages masqués.Masks as Ironie ProcessSome Makishi of Northwestern ZambiaThe using of masks during the initiation rites in Northwestern Zambia is part of a tradition loaded with rich symbolic meanings based on myths and social relationships. This article seeks to illustrate the use and rôles played by the same masks in the present-day political postcolonial contexts. The traditional masks fonn an important " locus " through wich people cope with and appropriate ironically the new poh'tical realities of the région

    A quantitative approach to study indirect effects among disease proteins in the human protein interaction network

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    <p>Abstract</p> <p>Background</p> <p>Systems biology makes it possible to study larger and more intricate systems than before, so it is now possible to look at the molecular basis of several diseases in parallel. Analyzing the interaction network of proteins in the cell can be the key to understand how complex processes lead to diseases. Novel tools in network analysis provide the possibility to quantify the key interacting proteins in large networks as well as proteins that connect them. Here we suggest a new method to study the relationships between topology and functionality of the protein-protein interaction network, by identifying key mediator proteins possibly maintaining indirect relationships among proteins causing various diseases.</p> <p>Results</p> <p>Based on the i2d and OMIM databases, we have constructed (i) a network of proteins causing five selected diseases (DP, disease proteins) plus their interacting partners (IP, non-disease proteins), the DPIP network and (ii) a protein network showing only these IPs and their interactions, the IP network. The five investigated diseases were (1) various cancers, (2) heart diseases, (3) obesity, (4) diabetes and (5) autism. We have quantified the number and strength of IP-mediated indirect effects between the five groups of disease proteins and hypothetically identified the most important mediator proteins linking heart disease to obesity or diabetes in the IP network. The results present the relationship between mediator role and centrality, as well as between mediator role and functional properties of these proteins.</p> <p>Conclusions</p> <p>We show that a protein which plays an important indirect mediator role between two diseases is not necessarily a hub in the PPI network. This may suggest that, even if hub proteins and disease proteins are trivially of great interest, mediators may also deserve more attention, especially if disease-disease associations are to be understood. Identifying the hubs may not be sufficient to understand particular pathways. We have found that the mediators between heart diseases and obesity, as well as heart diseases and diabetes are of relatively high functional importance in the cell. The mediator proteins suggested here should be experimentally tested as products of hypothetical disease-related proteins.</p

    Three Short Period Jupiters from TESS

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    We report the confirmation and mass determination of three hot Jupiters discovered by the Transiting Exoplanet Survey Satellite (TESS) mission: HIP 65Ab (TOI-129, TIC-201248411) is an ultra-short-period Jupiter orbiting a bright (V=11.1 mag) K4-dwarf every 0.98 days. It is a massive 3.213 +/- 0.078 Mjup planet in a grazing transit configuration with an impact parameter of b = 1.17 +0.10/-0.08. As a result the radius is poorly constrained, 2.03 +0.61/-0.49 Rjup. The planet's distance to its host star is less than twice the separation at which it would be destroyed by Roche lobe overflow. It is expected to spiral into HIP 65A on a timescale ranging from 80 Myr to a few gigayears, assuming a reduced tidal dissipation quality factor of Qs' = 10^7 - 10^9. We performed a full phase-curve analysis of the TESS data and detected both illumination- and ellipsoidal variations as well as Doppler boosting. HIP 65A is part of a binary stellar system, with HIP 65B separated by 269 AU (3.95 arcsec on sky). TOI-157b (TIC 140691463) is a typical hot Jupiter with a mass of 1.18 +/- 0.13 Mjup and a radius of 1.29 +/- 0.02 Rjup. It has a period of 2.08 days, which corresponds to a separation of just 0.03 AU. This makes TOI-157 an interesting system, as the host star is an evolved G9 sub-giant star (V=12.7). TOI-169b (TIC 183120439) is a bloated Jupiter orbiting a V=12.4 G-type star. It has a mass of 0.79 +/- 0.06 Mjup and a radius of 1.09 +0.08/-0.05 Rjup. Despite having the longest orbital period (P = 2.26 days) of the three planets, TOI-169b receives the most irradiation and is situated on the edge of the Neptune desert. All three host stars are metal rich with [Fe/H] ranging from 0.18 - 0.24.Comment: Published in A&

    Three Short Period Jupiters from TESS. HIP 65Ab, TOI-157b and TOI-169b

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    We report the confirmation and mass determination of three hot Jupiters discovered by the Transiting Exoplanet Survey Satellite (TESS) mission: HIP 65Ab (TOI-129, TIC-201248411) is an ultra-short-period Jupiter orbiting a bright (V = 11.1 mag) K4-dwarf every 0.98 days. It is a massive 3.213 ± 0.078 M_J planet in a grazing transit configuration with an impact parameter of b = 1.17_(−0.08)^(+0.10). As a result the radius is poorly constrained, 2.03_(−0.49)^(+0.61)R_J. The planet’s distance to its host star is less than twice the separation at which it would be destroyed by Roche lobe overflow. It is expected to spiral into HIP 65A on a timescale ranging from 80 Myr to a few gigayears, assuming a reduced tidal dissipation quality factor of Qs′ = 10⁷ − 10⁹. We performed a full phase-curve analysis of the TESS data and detected both illumination- and ellipsoidal variations as well as Doppler boosting. HIP 65A is part of a binary stellar system, with HIP 65B separated by 269 AU (3.95 arcsec on sky). TOI-157b (TIC 140691463) is a typical hot Jupiter with a mass of 1.18 ± 0.13 M_J and a radius of 1.29 ± 0.02 R_J. It has a period of 2.08 days, which corresponds to a separation of just 0.03 AU. This makes TOI-157 an interesting system, as the host star is an evolved G9 sub-giant star (V = 12.7). TOI-169b (TIC 183120439) is a bloated Jupiter orbiting a V = 12.4 G-type star. It has a mass of 0.79 ±0.06 M_J and a radius of 1.09_(−0.05)^(+0.08)R_J. Despite having the longest orbital period (P = 2.26 days) of the three planets, TOI-169b receives the most irradiation and is situated on the edge of the Neptune desert. All three host stars are metal rich with [Fe / H] ranging from 0.18 to 0.24
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