23,172 research outputs found

    The Relationship Between Preferred Modal Learning Style and Patterns of Use and Completion of an Online Project Management Training Programme

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    This paper reports the results of a pilot study, conducted to observe and evaluate the patterns of use and completion of a set of project management units and to identify any relationships between these factors and learning style. The aim of the study was to gather data on which to base a subsequent software development project, based around personalising the learning materials. The participants were adult professionals employed in public sector organisations in the UK and the study was based within a real business e-learning environment. Data regarding preferred learning style was collected via a questionnaire and usage, progress and completion rates were gathered from computer logging data, with user permission. To assess preferred learning style, the VARK inventory (Fleming and Mills, 1992) was used; this categorises learners according to modal preference for learning: Visual, Auditory, Read/write and Kinaesthetic. The results showed that learners with a preferred Visual mode showed the best record for completions and were characterised by frequent usage, but for relatively shorter study durations. In contrast, learners preferring the Auditory modality had the lowest proportion of completions, and also this group logged on less frequently but for longer study periods. Learners with a preferred Kinaesthetic mode were characterised by the highest proportion of ā€˜In-Processā€™ learners (who were regularly using the system but not yet completed). The paper concludes with a proposal to build a personalisable learning environment incorporating specific modal features. A further study will then observe more closely the interaction between preferred modal learning style, mode of presentation and usage and performance. Keywords: VARK, modal learning style, business e-learning, project managemen

    Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series

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    OBJECTIVE: To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series. Design: Randomised, double blind, placebo controlled, parallel group, multicentre study. SETTING: Four general practices and a hospital ear, nose, and throat outpatient department. PARTICIPANTS: 51 patients with perennial allergic rhinitis. Intervention: Random assignment to an oral 30c homoeopathic preparation of principal inhalant allergen or to placebo. MAIN OUTCOME MEASURES: Changes from baseline in nasal inspiratory peak flow and symptom visual analogue scale score over third and fourth weeks after randomisation. RESULTS: Fifty patients completed the study. The homoeopathy group had a significant objective improvement in nasal airflow compared with the placebo group (mean difference 19.8 l/min, 95% confidence interval 10.4 to 29.1, P=0.0001). Both groups reported improvement in symptoms, with patients taking homoeopathy reporting more improvement in all but one of the centres, which had more patients with aggravations. On average no significant difference between the groups was seen on visual analogue scale scores. Initial aggravations of rhinitis symptoms were more common with homoeopathy than placebo (7 (30%) v 2 (7%), P=0.04). Addition of these results to those of three previous trials (n=253) showed a mean symptom reduction on visual analogue scores of 28% (10.9 mm) for homoeopathy compared with 3% (1.1 mm) for placebo (95% confidence interval 4.2 to 15.4, P=0.0007). CONCLUSION: The objective results reinforce earlier evidence that homoeopathic dilutions differ from placebo

    Measuring forces between protein fibers by microscopy

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    We propose a general scheme for measuring the attraction between mechanically frustrated semiflexible fibers by measuring their thermal fluctuations and shape. We apply this analysis to a system of sickle hemoglobin (HbS) fibers that laterally attract one another. These fibers appear to ā€œzipā€ together before reaching mechanical equilibrium due to the existence of cross-links into a dilute fiber network. We are also able to estimate the rigidities of the fibers. These rigidities are found to be consistent with sickle hemoglobin ā€œsingleā€ fibers 20 nm in diameter, despite recent experiments indicating that fiber bundling sometimes occurs. Our estimate of the magnitude of the interfiber attraction for HbS fibers is in the range 8 Ā± 7 kBT/Ī¼m, or 4 Ā± 3 kBT/Ī¼m if the fibers are assumed, a priori to be single fibers (such an assumption is fully consistent with the data). This value is sufficient to bind the fibers, overcoming entropic effects, although extremely chemically weak. Our results are compared to models for the interfiber attraction that include depletion and van der Waals forces. This technique should also facilitate a similar analysis of other filamentous protein assembles in the future, including Ī²-amyloid, actin, and tubulin

    Skycorr: A general tool for spectroscopic sky subtraction

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    Airglow emission lines, which dominate the optical-to-near-IR sky radiation, show strong, line-dependent variability on various time scales. Therefore, the subtraction of the sky background in the affected wavelength regime becomes a problem if plain sky spectra have to be taken at a different time as the astronomical data. A solution of this issue is the physically motivated scaling of the airglow lines in the plain sky data to fit the sky lines in the object spectrum. We have developed a corresponding instrument-independent approach based on one-dimensional spectra. Our code skycorr separates sky lines and sky/object continuum by an iterative approach involving a line finder and airglow line data. The sky lines are grouped according to their expected variability. The line groups in the sky data are then scaled to fit the sky in the science data. Required pixel-specific weights for overlapping groups are taken from a comprehensive airglow model. Deviations in the wavelength calibration are corrected by fitting Chebyshev polynomials and rebinning via asymmetric damped sinc kernels. The scaled sky lines and the sky continuum are subtracted separately. VLT X-Shooter data covering time intervals from two minutes to about one year were selected to illustrate the performance. Except for short time intervals of a few minutes, the sky line residuals were several times weaker than for sky subtraction without fitting. Further tests show that skycorr performs consistently better than the method of Davies (2007) developed for VLT SINFONI data.Comment: 17 pages, 18 figures, accepted for publication in A&

    An incremental strategy for calculating consistent discrete CFD sensitivity derivatives

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    In this preliminary study involving advanced computational fluid dynamic (CFD) codes, an incremental formulation, also known as the 'delta' or 'correction' form, is presented for solving the very large sparse systems of linear equations which are associated with aerodynamic sensitivity analysis. For typical problems in 2D, a direct solution method can be applied to these linear equations which are associated with aerodynamic sensitivity analysis. For typical problems in 2D, a direct solution method can be applied to these linear equations in either the standard or the incremental form, in which case the two are equivalent. Iterative methods appear to be needed for future 3D applications; however, because direct solver methods require much more computer memory than is currently available. Iterative methods for solving these equations in the standard form result in certain difficulties, such as ill-conditioning of the coefficient matrix, which can be overcome when these equations are cast in the incremental form; these and other benefits are discussed. The methodology is successfully implemented and tested in 2D using an upwind, cell-centered, finite volume formulation applied to the thin-layer Navier-Stokes equations. Results are presented for two laminar sample problems: (1) transonic flow through a double-throat nozzle; and (2) flow over an isolated airfoil

    A Multi-wavelength Study of the Host Environment of SMBHB 4C+37.11

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    4C+37.11, at z=0.055 shows two compact radio nuclei, imaged by VLBI at 7mas separation, making it the closest known resolved super-massive black hole binary (SMBHB). An important question is whether this unique object is young, caught on the way to a gravitational in-spiral and merger, or has `stalled' at 7pc. We describe new radio/optical/X-ray observations of the massive host and its surrounding X-ray halo. These data reveal X-ray/optical channels following the radio outflow and large scale edges in the X-ray halo. These structures are promising targets for further study which should elucidate their relationship to the unique SMBHB core.Comment: To appear in the Astrophysical Journa

    Smartphone-Based Prenatal Education for Parents with Preterm Birth Risk Factors

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    Objective To develop an educational mobile application (app) for expectant parents diagnosed with risk factors for premature birth. Methods Parent and medical advisory panels delineated the vision for the app. The app helps prepare for preterm birth. For pilot testing, obstetricians offered the app between 18ā€“22 weeks gestational age to English speaking parents with risk factors for preterm birth. After 4 weeks of use, each participant completed a questionnaire. The software tracked topics accessed and duration of use. Results For pilot testing, 31 participants were recruited and 28 completed the questionnaire. After app utilization, participants reported heightened awareness of preterm birth (93%), more discussion of pregnancy or prematurity issues with partner (86%), increased questions at clinic visits (43%), and increased anxiety (21%). Participants reported receiving more prematurity information from the app than from their healthcare providers. The 15 participants for whom tracking data was available accessed the app for an average of 8ā€‰h. Conclusion Parents with increased risk for preterm birth may benefit from this mobile app educational program. Practice implications If the pregnancy results in preterm birth hospitalization, parents would have built a foundation of knowledge to make informed medical care choices
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