2,496 research outputs found
What is the significance of poetry for theology today?
Joan Jones begins this essay by exploring what is meant by the terms âtheologyâ and âpoetryâ. âTheologyâ is defined as the disciplined attempts of human beings to understand God. That is, the effort to understand how the world is affected by Godâs presence and activity, what kind of God he is, and what his purpose is. Jones then turns to how a knowledge of God might be expressed. Might this be poetically? This could be of help in theologyâs disciplined search for perfect expression. The fact is, however, that theology and poetry have always worked together, be it in Scripture, liturgy or psalms and hymns. In turn, poetry often expresses theological truths. Is poetry, then, more significant than theology in the early twenty-first century? Jones answers this question by observing that, currently, personal self-definition is much more likely to take place through subjective means than through social objectivity, as was once the case. Jones concludes by pointing to the great outpouring of new liturgy evidenced in praise songs and poetry, which demonstrate both the potential of faithâs reality and relevance and its significance for twenty-first-century theology.Publisher PD
A Study to Determine if Telecommunications Can Be Used as a Medium to Teach Basic Literacy Skills to Illiterate Adults in Virginia
The following goals were selected to guide this study: 1. Determine which methods have been used and how successful they have been in the past to teach basic literacy skills to illiterate adults; 2. Determine the methods currently being used to supplement classroom instruction; 3. Determine how receptive adults are to self-paced, self-directed methods; 4. Determine the type of problems experienced using telecommunications to teach literacy skills
The hospital and the community: a study of hospital community relations both at its inception and at present, and a proposal of a new approach to hospital-community relations as seen through a public relations case study of one voluntary institution
Thesis (M.S.)--Boston Universit
HOG PRODUCER INVESTMENT IN VALUE-ADDED AGRIBUSINESS: RISK AND RETURN IMPLICATIONS
Although producers have been enticed into investment in value-added agribusiness the risk and return impacts have not been quantified. A spreadsheet simulation model is used to evaluate how investments by hog farmers in slaughter plants and other alternatives affect returns and risk. Results suggest that hog producer investment in value-added agribusiness is efficient.Value-Added, Producer Investment, Financial Economics, Livestock Production/Industries,
He Taonga Tuku IhĆ no NgÄ TĆ«puna: MÄori Proverbial Sayings â a Literary Treasure
An address given on conferment of the degree of Honorary Doctor of Literature by Victoria University of Wellington, 16 April 199
Position paper: International Centre for Transformational Entrepreneurship, Coventry University
Gender and Corporate Sustainability: On Values, Vision, and Voice
This article presents an exploratory empirical study of the role of gender in sustainability initiatives and practices in a sample of 925 men and women from American companies. We explore gender differences and their implications for sustainability values, priorities, and perceptions of sustainability-related activities in the workplace. Drawing from studies of sustainability, gender, and environmental values and action, our study finds that corporate women hold sustainability-related concerns and values to be significantly more important to them personally than do their male colleagues, and they view and evaluate their companiesâ sustainability-related value priorities, initiatives, and activities from these foundational ethical and value orientations. We conclude with a research agenda that includes identifying the actual participation of women in corporate sustainability initiatives, and also the organizational enablers and impediments of their empowered action and leadership
Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of G(i)- and G(q)-mediated signaling
RGS proteins (Regulators of G protein Signaling) are a recently discovered family of proteins that accelerate the GTPase activity of heterotrimeric G protein α subunits of the i, q, and 12 classes. The proteins share a homologous core domain but have divergent amino-terminal sequences that are the site of palmitoylation for RGS-GAIP and RGS4. We investigated the function of palmitoylation for RGS16, which shares conserved amino-terminal cysteines with RGS4 and RGS5. Mutation of cysteine residues at residues 2 and 12 blocked the incorporation of [3H]palmitate into RGS16 in metabolic labeling studies of transfected cells or into purified RGS proteins in a cell-free palmitoylation assay. The purified RGS16 proteins with the cysteine mutations were still able to act as GTPase-activating protein for Giα. Inhibition or a decrease in palmitoylation did not significantly change the amount of protein that was membrane-associated. However, palmitoylation-defective RGS16 mutants demonstrated impaired ability to inhibit both Gi- and Gq-linked signaling pathways when expressed in HEK293T cells. These findings suggest that the amino-terminal region of RGS16 may affect the affinity of these proteins for Gα subunits in vivo or that palmitoylation localizes the RGS protein in close proximity to Gα subunits on cellular membranes
A holistic in silico approach to predict functional sites in protein structures
Abstract
Motivation: Proteins execute and coordinate cellular functions by interacting with other biomolecules. Among these interactions, proteinâprotein (including peptide-mediated), proteinâDNA and proteinâRNA interactions cover a wide range of critical processes and cellular functions. The functional characterization of proteins requires the description and mapping of functional biomolecular interactions and the identification and characterization of functional sites is an important step towards this end.
Results: We have developed a novel computational method, Multi-VORFFIP (MV), a tool to predicts protein-, peptide-, DNA- and RNA-binding sites in proteins. MV utilizes a wide range of structural, evolutionary, experimental and energy-based information that is integrated into a common probabilistic framework by means of a Random Forest ensemble classifier. While remaining competitive when compared with current methods, MV is a centralized resource for the prediction of functional sites and is interfaced by a powerful web application tailored to facilitate the use of the method and analysis of predictions to non-expert end-users.
Availability: Â http://www.bioinsilico.org/MVORFFIP
Supplementary information: Â Supplementary data are available at Bioinformatics online.
Contact: Â [email protected]; [email protected]</jats:p
- âŠ