2,272 research outputs found

    A Racial Impact Analysis of HB 869/SB 274

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    Virginia is growing. Between 1990 and 2000, Virginia’s population rose by over 14% - the largest population growth experienced by the state in a single decade (Pollard, 2007). And the state continues to grow. It has been estimated that by 2030, Virginia’s total population may exceed 9.8 million people (Pollard, 2007). Along with population growth, land development has increased which in turn affects transportation, housing and job placement across the Commonwealth. In fact, in many parts of the state, development has outpaced population growth. According to Pollard, “If current patterns continue, Virginia will develop more land in the next 40 years than in the previous 400 years (p.8).” In an effort to curb sprawling development and decrease transportation expenditure, the Virginia General Assembly passed House Bill 3202 in 2007. One major outcome of this multifaceted legislation was the introduction of mandatory Urban Development Areas (UDAs). The goal of UDAs was for localities to concentrate growth and development in order to reduce the cost of transportation and increase opportunities to build multi-use developments and expand affordable housing. In 2012, the General Assembly passed House Bill 869 and Senate Bill 274 which effectively make UDAs no longer mandatory but optional for all localities in the Commonwealth. In this paper, we analyze the racial impact and explore the political history of HB 869/SB 274 while addressing the larger issue of sprawl across the Commonwealth. Smart Growth policies are known to positively impact the environment but they also positively impact low-income and minority communities by increasing access to housing, transportation and ultimately jobs. The story behind Urban Development Areas in the Commonwealth is one of politics and regulation but issues as critical as housing, transportation and job access should be focused much more on the citizens of the Commonwealth. The friction created by the UDA policy between the localities and the state has the potential to spark a statewide conversation about land use and more importantly - the need for people-centered solutions to a growing problem

    Hypoglycemic Effect of Gongronema latifolia Extracts in Rats

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    Phytochemistry and hypoglycemic effect of the water and Ethanolic Extracts of the leaves of Gongronema latifolium were screened for. The extracts were Soxhlet extracted and phytochemically screened. Three tolerated doses were estimated from acute toxicity studies and orally administered to three groups of 10 rats per group, daily for 21 days. After treatments, rats of groups 1 to 3 were sacrificed and blood samples collected for glucose analysis and was compared to control group 4. Phytochemistry reveals that, both extracts of the plant contain predominant amount of Saponins and Polyphenols among other phytochemicals. Glucose analysis shows dose related reduction in the blood glucose levels compared to control. The polyphenols content of the plant extracts could cause the hypoglycemic effect observed, suggesting insulin-like activity which justifies the use of the plant leaf in the management of diabetic Mellitus in Nigeria herbal medicine. Keywords: Phytochemistry, phytopharmacology, hypoglycemia, extracts, Gongronema latifoliu

    Make Art Real

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    The Make Art Real project aims to introduce new audiences to the arts. It supports Theme II of VCU’s Quest for Distinction by promoting and fostering creative expression through innovative collaborations. The project involves displaying existing connections between art and non-art disciplines, as well as making new connections. These unusual pairings are then placed on exhibition through a lunch-time lecture series named “Unexpected_Connections,” which allow faculty, staff, and students to lead and participate in discussions about the reality of art. The lecture series is the first sustainable and reoccurring program to be held in the Depot building, a multidisciplinary facility which is intended to foster interdisciplinary collaborations. The targeted audience includes faculty, staff, students, and members of the greater VCU community

    Structural analysis of the starfish SALMFamide neuropeptides S1 and S2: The N-terminal region of S2 facilitates self-association

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    The neuropeptides S1 (GFNSALMFamide) and S2 (SGPYSFNSGLTFamide), which share sequence similarity, were discovered in the starfish Asterias rubens and are prototypical members of the SALMFamide family of neuropeptides in echinoderms. SALMFamide neuropeptides act as muscle relaxants and both S1 and S2 cause relaxation of cardiac stomach and tube foot preparations in vitro but S2 is an order of magnitude more potent than S1. Here we investigated a structural basis for this difference in potency using spectroscopic techniques. Circular dichroism spectroscopy showed that S1 does not have a defined structure in aqueous solution and this was supported by 2D nuclear magnetic resonance experiments. In contrast, we found that S2 has a well-defined conformation in aqueous solution. However, the conformation of S2 was concentration dependent, with increasing concentration inducing a transition from an unstructured to a structured conformation. Interestingly, this property of S2 was not observed in an N-terminally truncated analogue of S2 (short S2 or SS2; SFNSGLTFamide). Collectively, the data obtained indicate that the N-terminal region of S2 facilitates peptide self-association at high concentrations, which may have relevance to the biosynthesis and/or bioactivity of S2 in vivo

    A systematic review of barriers to early presentation and diagnosis with cancer among Black women

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    Objective: To explore barriers to early presentation and diagnosis with breast cancer among black women. Design: Systematic review. Methods: We searched multiple bibliographic databases (January 1991–February 2013) for primary research, published in English, conducted in developed countries and investigating barriers to early presentation and diagnosis with symptomatic breast cancer among black women (?18 years). Studies were excluded if they did not report separate findings by ethnic group or gender, only reported differences in time to presentation/diagnosis, or reported on interventions and barriers to cancer screening. We followed Cochrane and PRISMA guidance to identify relevant research. Findings were integrated through thematic synthesis. Designs of quantitative studies made meta-analysis impossible. Results: We identified 18 studies (6183 participants). Delay was multifactorial, individual and complex. Factors contributing to delay included: poor symptom and risk factor knowledge; fear of detecting breast abnormality; fear of cancer treatments; fear of partner abandonment; embarrassment disclosing symptoms to healthcare professionals; taboo and stigmatism. Presentation appears quicker following disclosure. Influence of fatalism and religiosity on delay is unclear from evidence in these studies. We compared older studies (?10 years) with newer ones (<10 years) to determine changes over time. In older studies, delaying factors included: inaccessibility of healthcare services; competing priorities and concerns about partner abandonment. Partner abandonment was studied in older studies but not in newer ones. Comparisons of healthy women and cancer populations revealed differences between how people perceive they would behave, and actually behave, on finding breast abnormality. Conclusions: Strategies to improve early presentation and diagnosis with breast cancer among black women need to address symptom recognition and interpretation of risk, as well as fears of the consequences of cancer. The review is limited by the paucity of studies conducted outside the USA and limited detail reported by published studies preventing comparison between ethnic groups

    GeneLink: a database to facilitate genetic studies of complex traits

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    BACKGROUND: In contrast to gene-mapping studies of simple Mendelian disorders, genetic analyses of complex traits are far more challenging, and high quality data management systems are often critical to the success of these projects. To minimize the difficulties inherent in complex trait studies, we have developed GeneLink, a Web-accessible, password-protected Sybase database. RESULTS: GeneLink is a powerful tool for complex trait mapping, enabling genotypic data to be easily merged with pedigree and extensive phenotypic data. Specifically designed to facilitate large-scale (multi-center) genetic linkage or association studies, GeneLink securely and efficiently handles large amounts of data and provides additional features to facilitate data analysis by existing software packages and quality control. These include the ability to download chromosome-specific data files containing marker data in map order in various formats appropriate for downstream analyses (e.g., GAS and LINKAGE). Furthermore, an unlimited number of phenotypes (either qualitative or quantitative) can be stored and analyzed. Finally, GeneLink generates several quality assurance reports, including genotyping success rates of specified DNA samples or success and heterozygosity rates for specified markers. CONCLUSIONS: GeneLink has already proven an invaluable tool for complex trait mapping studies and is discussed primarily in the context of our large, multi-center study of hereditary prostate cancer (HPC). GeneLink is freely available at

    The Iowa Homemaker vol.5, no.11

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    Table of Contents Choosing the Profession of Homemaking by Anna E. Richardson, page 1 Opportunities Offered in Hospital Dietetics by Grace Magee, page 2 Selecting Your Spring Wardrobe by Betty Barker, page 2 Soft Water for the Housewife by Arthur W. Turner, page 3 Do You Have a Tea Room Complex? by Gladys Branson, page 4 The Designer – Her Place by Helen Dahl, page 4 Girls’ 4-H Page, page 5 With the Iowa State Home Economics Association, page 6 Editorial, page 7 Who’s There and Where, page 8 Marketing as a Business Proposition by Ruetta Day Blinks, page 9 The Eternal Question, page 10 Are You Furnishing Your Home?, page 11 The Heart of the Home by Frances Jones, page 1

    Transfer Student Peer Mentorship Initiative

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    Transfer students have unique needs that differ from those of incoming freshmen. The TRAM Transfer Student Mentorship Program connects incoming transfer students with students who also began their VCU journey as transfer students. Through a one-on-one relationship with a trained mentor, transfer students who participate in this program will access guidance and information to help them navigate the university and its resources, programs, and culture

    Bridging the Gaps: Building a University Link Tank

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    This project proposed a University Link Tank as a mechanism by which to build bridges between employees via a network of small groups. Participation in the Link Tank would be voluntary and open to all VCU and Health System employees. The program would be modeled similarly to the Faculty Learning Community (FLC) program, which is administered by the Center for Teaching Excellence, but it would concentrate on issues that are not specifically related to teaching. Topics will be proposed annually. The program would also concentrate on effectively utilizing existing VCU resources to resolve issues

    Late Miocene to early Pliocene biofacies of Wanganui and Taranaki Basins, New Zealand: Applications to paleoenvironmental and sequence stratigraphic analysis

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    The Matemateaonga Formation is late Miocene to early Pliocene (upper Tongaporutuan to lower Opoitian New Zealand Stages) in age. The formation comprises chiefly shellbeds, siliciclastic sandstone, and siltstone units and to a lesser extent non-marine and shallow marine conglomerate and rare paralic facies. The Matemateaonga Formation accumulated chiefly in shelf paleoenvironments during basement onlap and progradation of a late Miocene to early Pliocene continental margin wedge in the Wanganui and Taranaki Basins. The formation is strongly cyclothemic, being characterised by recurrent vertically stacked facies successions, bounded by sequence boundaries. These facies accumulated in a range of shoreface to mid-outer shelf paleoenvironments during conditions of successively oscillating sea level. This sequential repetition of facies and the biofacies they enclose are the result of sixth-order glacio-eustatic cyclicity. Macrofaunal associations have been identified from statistical analysis of macrofossil occurrences collected from multiple sequences. Each association is restricted to particular lithofacies and stratal positions and shows a consistent order and/or position within the sequences. This pattern of temporal paleoecologic change appears to be the result of lateral, facies-related shifting of broad biofacies belts, or habitat-tracking, in response to fluctuations of relative sea level, sediment flux, and other associated paleoenvironmental variables. The associations also show strong similarity in terms of their generic composition to biofacies identified in younger sedimentary strata and the modern marine benthic environment in New Zealand
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