Kako budući stručnjaci u sportu, tjelovježbi i tjelesnome odgoju percipiraju tjelesni izgled pretile djece

Anti-fat bias has been previously identified amongst practising obesity health care specialists, physical education (PE) teachers and students of exercise science and PE in samples in the USA and New Zealand. The present research investigated the perceptions of the physical self of ‘fat’ versus ‘normal-weight’ children held by 167 students studying sport exercise and PE related programmes in higher education in England. Onesample t-tests identified that the sample held negative perceptions towards ‘fat’ children (identified by subscale mean scores that were significantly different from the subscale mean of 2.5 that would identify equivocal perception between ‘fat’ and ‘normal-weight’ children) on five of the six subscales of an adapted version of the Children & Youth Physical Self Perception Profile (CONDITION 1.52±.49; BODY 1.63±.43; PHYSICAL SELF-WORTH 1.79±.47; SPORT 1.88±.45; GLOBAL SELF-ESTEEM 2.10±.50, all p<.01; STRENGTH 2.48±.52, p=.67). Such results are indicative of the obesity discourse that currently prevails within PE and sport professions; a discourse constructed, arguably, on misleading foundations. Obesity awareness training is, therefore, required in such trainee exercise science, sport and PE populations. Pedagogical approaches espoused during programmes of study ought to emphasize personal meaning, personal reference and childcenteredness so that such approaches are more likely to be employed in their future professional practice.Predrasude prema pretilim ljudima utvrđene su kod specijalista zdravstvene skrbi koji se bave pretilošću, kod profesora tjelesne i zdravstvene kulture te studenata kineziologije u SAD-u i Novom Zelandu. Cilj provedenog istraživanja bio je utvrditi percepcije tjelesnog izgleda “debele” u odnosu na djecu “normalne težine” kod 167 studenata kineziologije (sporta, vježbanja i fizičke kulture) u Engleskoj. Rezultati t-testova su pokazali da su ispitanici imali negativnu percepciju pretile djece (utvrđeno srednjim vrijednostima podljestvice koje su se statistički značajno razlikovale od njezine aritmetičke sredine (2,5) koja bi potvrdila jednaku percepciju pretile djece i djece normalne težine), na pet od ukupno šest podljestvica adaptirane verzije upitnika Children & Youth Physical Self Perception Profile (kondicijska pripremljenost 1.52±.49; slika tijela 1.63±.43; tjelesno samovrednovanje 1.79±.47; sportska kompetencija 1.88±.45; opće samopouzdanje 2.10±.50, svi na razini značajnosti p<.01; te tjelesna jakost i snaga 2.48±.52, p=.67). Dobiveni rezultati su indikativni za odnos prema pretilim osobama koji trenutno prevladava kod profesionalnih djelatnika u sportu i tjelesnoj i zdravstvenoj kulturi, a koji je nedvojbeno izgrađen na pogrešnim temeljima. Stoga je za populacije pripravnika u kineziologiji, sportu i tjelesnoj i zdravstvenoj kulturi potrebna edukacija i razvoj svijesti o pretilosti. Pedagoški pristupi koji se provode u okviru studijskih programa trebali bi naglasiti osobnost pojedinca, te osobni odnos i orijentaciju prema djetetu kako bi takvi pristupi i takav odnos prema djeci bili i primijenjeni u budućem profesionalnom radu sportskih stručnjaka i znanstvenika

Double Diffusion Encoding Prevents Degeneracy in Parameter Estimation of Biophysical Models in Diffusion MRI

Purpose: Biophysical tissue models are increasingly used in the interpretation of diffusion MRI (dMRI) data, with the potential to provide specific biomarkers of brain microstructural changes. However, the general Standard Model has recently shown that model parameter estimation from dMRI data is ill-posed unless very strong magnetic gradients are used. We analyse this issue for the Neurite Orientation Dispersion and Density Imaging with Diffusivity Assessment (NODDIDA) model and demonstrate that its extension from Single Diffusion Encoding (SDE) to Double Diffusion Encoding (DDE) solves the ill-posedness and increases the accuracy of the parameter estimation. Methods: We analyse theoretically the cumulant expansion up to fourth order in b of SDE and DDE signals. Additionally, we perform in silico experiments to compare SDE and DDE capabilities under similar noise conditions. Results: We prove analytically that DDE provides invariant information non-accessible from SDE, which makes the NODDIDA parameter estimation injective. The in silico experiments show that DDE reduces the bias and mean square error of the estimation along the whole feasible region of 5D model parameter space. Conclusions: DDE adds additional information for estimating the model parameters, unexplored by SDE, which is enough to solve the degeneracy in the NODDIDA model parameter estimation.Comment: 22 pages, 7 figure

Meyer's loop tractography for image-guided surgery depends on imaging protocol and hardware

Introduction Surgical resection is an effective treatment for temporal lobe epilepsy but can result in visual field defects. This could be minimized if surgeons knew the exact location of the anterior part of the optic radiation (OR), the Meyer's loop. To this end, there is increasing prevalence of image-guided surgery using diffusion MRI tractography. Despite considerable effort in developing analysis methods, a wide discrepancy in Meyer's loop reconstructions is observed in the literature. Moreover, the impact of differences in image acquisition on Meyer's loop tractography remains unclear. Here, while employing the same state-of-the-art analysis protocol, we explored the extent to which variance in data acquisition leads to variance in OR reconstruction. Methods Diffusion MRI data were acquired for the same thirteen healthy subjects using standard and state-of-the-art protocols on three scanners with different maximum gradient amplitudes (MGA): Siemens Connectom (MGA = 300 mT/m); Siemens Prisma (MGA = 80 mT/m) and GE Excite-HD (MGA = 40 mT/m). Meyer's loop was reconstructed on all subjects and its distance to the temporal pole (ML-TP) was compared across protocols. Results A significant effect of data acquisition on the ML-TP distance was observed between protocols (p < .01 to 0.0001). The biggest inter-acquisition discrepancy for the same subject across different protocols was 16.5 mm (mean: 9.4 mm, range: 3.7–16.5 mm). Conclusion We showed that variance in data acquisition leads to substantive variance in OR tractography. This has direct implications for neurosurgical planning, where part of the OR is at risk due to an under-estimation of its location using conventional acquisition protocols

Integrating Automation into a Multi-Mission Operations Center

NASA Goddard Space Flight Center's Space Science Mission Operations (SSMO) Project is currently tackling the challenge of minimizing ground operations costs for multiple satellites that have surpassed their prime mission phase and are well into extended mission. These missions are being reengineered into a multi-mission operations center built around modern information technologies and a common ground system infrastructure. The effort began with the integration of four SMEX missions into a similar architecture that provides command and control capabilities and demonstrates fleet automation and control concepts as a pathfinder for additional mission integrations. The reengineered ground system, called the Multi-Mission Operations Center (MMOC), is now undergoing a transformation to support other SSMO missions, which include SOHO, Wind, and ACE. This paper presents the automation principles and lessons learned to date for integrating automation into an existing operations environment for multiple satellites

Financial Analysis of Dalbavancin for Acute Bacterial Skin and Skin Structure Infections for Self-Pay Patients

© 2020, The Author(s). Introduction: Acute bacterial skin and skin structure infections (ABSSSI) are an increasing cause of admission in the self-pay population. We previously reported that patients with ABSSSI discharged to receive dalbavancin showed a decreased length of stay (LOS) and total direct costs without increasing 30-day readmission rate. For patients who are financially eligible, a dalbavancin vial replacement program can offset costs. The objective of this study was to determine cost differences in treating ABSSSI in self-pay inpatients discharged to receive dalbavancin compared to standard of care (SOC). Methods: This retrospective cohort within a community health system compared self-pay adult inpatients with ABSSSI from February 3, 2016 to August 5, 2019 discharged to receive dalbavancin at an outpatient infusion center with SOC intravenous antibiotics. Patients were included with cellulitis, abscess, or postoperative wound infections diagnoses on the basis of International Classification of Disease, Tenth Revision (ICD-10) codes. Excluded populations were patients without dalbavancin vial replacement performed, pregnant, infections caused exclusively by gram-negative bacteria or fungi, or ICD-10 codes not consistent with ABSSSI. The primary outcome was direct cost of hospital stay. Secondary outcomes included length of stay (LOS), 30-day readmission rates, adverse events (AE), and indirect hospital costs. On the basis of previous studies, a one-sided Student’s t test was performed on financial data. Results: Twelve dalbavancin and 263 SOC patients met inclusion criteria. Direct cost ($2758 vs$4010, p = 0.105) and indirect hospital cost ($2913 vs$3646 , p = 0.162) per patient were less in the dalbavancin group. There was no significant difference between median LOS (4 vs 4, p = 0.888), AE (0% vs 14.8%), and 30-day readmission rates for dalbavancin vs SOC group (8.3% vs 7.2%, p = 0.604). Conclusion: Self-pay patients with ABSSSI discharged to receive dalbavancin with vial replacement resulted in decreased direct and indirect costs per patient with similar 30-day readmission rates, AE, and LOS. More studies targeted toward this population are warranted to determine ultimate benefit

GeneLink: a database to facilitate genetic studies of complex traits

BACKGROUND: In contrast to gene-mapping studies of simple Mendelian disorders, genetic analyses of complex traits are far more challenging, and high quality data management systems are often critical to the success of these projects. To minimize the difficulties inherent in complex trait studies, we have developed GeneLink, a Web-accessible, password-protected Sybase database. RESULTS: GeneLink is a powerful tool for complex trait mapping, enabling genotypic data to be easily merged with pedigree and extensive phenotypic data. Specifically designed to facilitate large-scale (multi-center) genetic linkage or association studies, GeneLink securely and efficiently handles large amounts of data and provides additional features to facilitate data analysis by existing software packages and quality control. These include the ability to download chromosome-specific data files containing marker data in map order in various formats appropriate for downstream analyses (e.g., GAS and LINKAGE). Furthermore, an unlimited number of phenotypes (either qualitative or quantitative) can be stored and analyzed. Finally, GeneLink generates several quality assurance reports, including genotyping success rates of specified DNA samples or success and heterozygosity rates for specified markers. CONCLUSIONS: GeneLink has already proven an invaluable tool for complex trait mapping studies and is discussed primarily in the context of our large, multi-center study of hereditary prostate cancer (HPC). GeneLink is freely available at

Bis(μ-disulfur dinitrido)bis­[diphenyl­tin(IV)]

The title compound, [Sn2(C6H5)4(N2S2)2], exists as a centrosymmetric binuclear dimer with the SnIV centres in distorted trigonal bipyramidal geometry and a central Sn2N2 core