Ein Stachel im Gedächtnis der Stadt. Der Abriss des Hamburger Doms

Der vierte Teil der Hamburgischen Kirchengeschichte in Aufsätzen ist dem 19. Jahrhundert gewidmet. Angesichts der folgenreichen Auf- und Umbrüche, der vielen wichtigen Themen und prägenden Gestalten bilden die hier wieder abgedruckten oder neu verfassten Texte nur einige der für die Kirchengeschichte Hamburgs in dieser bewegten Epoche einschlägigen Ereignisse und Entwicklungen ab. Ungeachtet aller Ergänzungsmöglichkeiten bietet dieser Band zahlreiche neue wie erhellende Einblicke in den spannenden Urbanisierungsprozess einer Großstadt und ihrer Kirchen auf ihrem von Katastrophen und Glücksfällen, von Reformeifer und Konservativismus gleichermaßen gezeichneten Weg in die Moderne.The fourth part of Hamburg\u27s church history in essays is dedicated to the 19th century. Considering the momentous upheavals and upheavals and the variety of important themes and formative figures, the texts reprinted or newly written here reflect only some of the events and developments relevant to Hamburg\u27s church history in this eventful epoch. Irrespective of all possible additions, this volume offers numerous new and enlightening insights into the exciting urbanization process of a city and its churches on their path to modernity, marked by catastrophes and fortunes, reformist zeal and conservatism

Magnetic Resonance Imaging of the Axial Skeleton in Patients With Spondyloarthritis: Distribution Pattern of Inflammatory and Structural Lesions

Purpose: Spondyloarthritis is a chronic inflammatory disorder of the musculoskeletal system driven by systemic enthesitis and typically involving the axial skeleton, ie, the spine and the sacroiliac joints. The purpose of this study was to assess the distribution pattern of inflammatory and structural magnetic resonance imaging (MRI) findings in spondyloarthritis. Methods: Retrospective study of 193 patients with axial spondyloarthritis who received MRI of the spine and the sacroiliac joints. We quantitatively assessed inflammatory and structural lesions using established MRI-based scoring methods. The significance of the differences between gender, HLA-B27 status, and spine and sacroiliac involvement was determined. Results: In total, 174 patients (90.2%) showed a sacroiliac involvement and 120 patients (62.2%) a combined involvement of the sacroiliac joints and the spine. An isolated sacroiliac involvement was found in 54 patients (28.0%) and an isolated spine involvement in 19 patients (9.8%). The sacroiliac joint was significantly more involved in men than in women (P < .01), and men had significantly higher scores for structural lesions (P < .001). The subgroup of HLA-B27–positive patients showed a significantly higher percentage of sacroiliac involvement compared with HLA-B27–negative patients (P < .05). Conclusions: Spondyloarthritis is a systemic disorder predominantly involving the sacroiliac joints. However, the entire axial skeleton may be affected. In particular, HLA-B27–negative women show atypical manifestations without sacroiliac involvement. Magnetic resonance imaging in spondyloarthritis should cover the entire axial skeleton, ie, sacroiliac joints and the spine to meet the pathophysiology of this disorder and capture the true extent of inflammatory and structural lesions

Hamburgische Kirchengeschichte in Aufsätzen ‒ bisher erschienene Bände

Der vierte Teil der Hamburgischen Kirchengeschichte in Aufsätzen ist dem 19. Jahrhundert gewidmet. Angesichts der folgenreichen Auf- und Umbrüche, der vielen wichtigen Themen und prägenden Gestalten bilden die hier wieder abgedruckten oder neu verfassten Texte nur einige der für die Kirchengeschichte Hamburgs in dieser bewegten Epoche einschlägigen Ereignisse und Entwicklungen ab. Ungeachtet aller Ergänzungsmöglichkeiten bietet dieser Band zahlreiche neue wie erhellende Einblicke in den spannenden Urbanisierungsprozess einer Großstadt und ihrer Kirchen auf ihrem von Katastrophen und Glücksfällen, von Reformeifer und Konservativismus gleichermaßen gezeichneten Weg in die Moderne.The fourth part of Hamburg\u27s church history in essays is dedicated to the 19th century. Considering the momentous upheavals and upheavals and the variety of important themes and formative figures, the texts reprinted or newly written here reflect only some of the events and developments relevant to Hamburg\u27s church history in this eventful epoch. Irrespective of all possible additions, this volume offers numerous new and enlightening insights into the exciting urbanization process of a city and its churches on their path to modernity, marked by catastrophes and fortunes, reformist zeal and conservatism

Effect of tube diameter and capillary number on platelet margination and near-wall dynamics

The effect of tube diameter $D$ and capillary number $Ca$ on platelet margination in blood flow at $\approx 37\%$ tube haematocrit is investigated. The system is modelled as three-dimensional suspension of deformable red blood cells and nearly rigid platelets using a combination of the lattice-Boltzmann, immersed boundary and finite element methods. Results show that margination is facilitated by a non-diffusive radial platelet transport. This effect is important near the edge of the cell-free layer, but it is only observed for $Ca > 0.2$, when red blood cells are tank-treading rather than tumbling. It is also shown that platelet trapping in the cell-free layer is reversible for $Ca \leq 0.2$. Only for the smallest investigated tube ($D = 10 \mu\text{m}$) margination is essentially independent of $Ca$. Once platelets have reached the cell-free layer, they tend to slide rather than tumble. The tumbling rate is essentially independent of $Ca$ but increases with $D$. Tumbling is suppressed by the strong confinement due to the relatively small cell-free layer thickness at $\approx 37\%$ tube haematocrit.Comment: 16 pages, 10 figure