Watch This Spot and Whose In It : Creating Space for Indigenous Educators?

Within Aotearoa/New Zealand, a bicultural relationship between Maori and Pakeha has produced a number of initiatives that are striving to be more inclusive of Maori needs, interests and language within the education system. The education system is attempting to ‘create space’ for Maori to be more proactively involved in decision-making forums with the integration of Maori knowledge and practices also occurring in areas like policy, research and teaching

Flooding of December 29, 1984 Through January 2, 1985, in Northern New York State, With Flood Profiles of the Black and Salmon Rivers

Precipitation, snowmelt, and resultant flooding throughout northern New York from December 28 through January 2, 1985, were investigated through a detailed analysis of 56 precipitation stations, 101 stage and/or discharge gaging stations, and 9 miscellaneous measurement sites. Flood damage to property and roads and bridges exceeded $5 million. Lewis and Oswego Counties were declared Federal disaster areas, primarily a result of flooding of the Black River and Salmon River. Storm-precipitation and runoff maps show the storms \u27 greatest intensity to have been over the Tug Hill and southwest Adirondack areas. Total rainfall from December 28 through January 2 was 6.90 inches at Stillwater Reservoir but only 0.69 inches at Lake Placid. New peak discharges of record occurred at 17 gaging stations throughout northern New York, and the maximum discharge at 17 sites had recurrence intervals equal to or greater than 100 years. Computed inflows to 11 major lakes and reservoirs in northern New York indicate that significant volumes of water (as much as 5 inches of storm runoff at Stillwater Reservoir) were stored during the storm-runoff period. Maximum 1-day flood volumes at two gaging stations on the Black River had recurrence intervals greater than 100 years. To help evaluate the extent of flooding, 67 floodmarks were obtained along a 94-mile reach of the Black River from Dexter to Forestport, and several floodmarks were surveyed within major communities along the Salmon River. The floodmarks were obtained primarily near major bridges and dams along these rivers. (Author \u27s abstract

The Role of Public and Private Insurance Expansions and Premiums for Low-Income Parents

Numerous states have implemented policies expanding public insurance eligibility or subsidizing private insurance for parents

Dysregulation of endothelial cell connexin-43 localisation in response to doxorubicin

Introduction: Anthracyclines, such as doxorubicin, remain an important class of chemotherapeutic agent however their efficacy in treating cancer is limited by a cumulative dose-dependent cardiotoxicity. Whilst most studies have focused on cardiomyocyte impairment, circulating doxorubicin has been shown to impact human microvascular responses to doxorubicin in coronary vessels.1 Studies show increased endothelial cell permeability resulting in increased paracellular permeability due to damage to the integrity of cell-cell junctions.2 Strategies to maintain vessel integrity and prevent endothelial cell dysregulation could represent a novel therapeutic opportunity to limit the toxic effects of doxorubicin. The aim of this project was to assess the impact of doxorubicin upon endothelial gap junction proteins, in particular connexin-43 (Cx43)

The specificity of pathogenic oxidative stress in schizophrenia

Abstract not available

A Randomized Controlled Dosing Study of Iyengar Yoga and Coherent Breathing for the Treatment of Major Depressive Disorder: Impact on Suicidal Ideation and Safety Findings

BACKGROUND: Yoga interventions offer promise for the treatment of major depressive disorder (MDD), yet their safety and potential impact on suicidal ideation (SI) have not been well documented. This study evaluated the safety of a randomized controlled dose-finding trial of Iyengar yoga plus coherent breathing for individuals with MDD, as well as the potential effects of the intervention on SI without intent. METHODS: Participants with Beck Depression Inventory-II (BDI-II) scores \u3e/=14 and a diagnosis of MDD (using DSM-IV criteria) were randomized to either a low dose group (LDG) or high dose group (HDG) and received a 12-week manualized intervention. The LDG included two 90-min yoga classes plus three 30-min homework sessions weekly. The HDG offered three 90-min classes plus four 30-min homework sessions weekly. RESULTS: Thirty-two individuals with MDD were randomized, of which 30 completed the protocol. At screening, SI without intent was endorsed on the BDI-II by 9 participants; after completing the intervention, 8 out of 9 reported resolution of SI. There were 17 adverse events possibly-related and 15 definitely-related to the intervention. The most common protocol-related adverse event was musculoskeletal pain, which resolved over the course of the study. CONCLUSIONS: The Iyengar yoga plus coherent breathing intervention was associated with the resolution of SI in 8 out of 9 participants, with mild side effects that were primarily musculoskeletal in nature. This preliminary evidence suggests that this intervention may reduce SI without intent and be safe for use in those with MDD

Enhancement of Antiferromagnetic Correlations Induced by Nonmagnetic Impurities: Origin and Predictions for NMR Experiments

Spin models that have been proposed to describe dimerized chains, ladders, two dimensional antiferromagnets, and other compounds are here studied when some spins are replaced by spinless vacancies, such as it occurs by $Zn$ doping. A small percentage of vacancies rapidly destroys the spin gap, and their presence induces enhanced antiferromagnetic correlations near those vacancies. The study is performed with computational techniques which includes Lanczos, world-line Monte Carlo, and the Density Matrix Renormalization Group methods. Since the phenomenon of enhanced antiferromagnetism is found to occur in several models and cluster geometries, a common simple explanation for its presence may exist. It is argued that the resonating-valence-bond character of the spin correlations at short distances of a large variety of models is responsible for the presence of robust staggered spin correlations near vacancies and lattice edges. The phenomenon takes place regardless of the long distance properties of the ground state, and it is caused by a ``pruning'' of the available spin singlets in the vicinity of the vacancies. The effect produces a broadening of the low temperature NMR signal for the compounds analyzed here. This broadening should be experimentally observable in the structurally dimerized chain systems $Cu(NO_3)_2\cdot2.5H_2O$, $CuWO_4$, $(VO)_2P_2O_7$, and $Sr_{14}Cu_{24}O_{41}$, in ladder materials such as $Sr Cu_2 O_3$, in the spin-Peierls systems $CuGeO_3$ and $NaV_2 O_5$, and in several others since it is a universal effect common to a wide variety of models and compounds.Comment: 18 pages revtex with 26 figures include

Contrast Limited Adaptive Histogram Equalization image processing to improve the detection of simulated spiculations in dense mammograms

The purpose of this project was to determine whether Contrast Limited Adaptive Histogram Equalization (CLAHE) improves detection of simulated spiculations in dense mammograms. Lines simulating the appearance of spiculations, a common marker of malignancy when visualized with masses, were embedded in dense mammograms digitized at 50 micron pixels, 12 bits deep. Film images with no CLAHE applied were compared to film images with nine different combinations of clip levels and region sizes applied. A simulated spiculation was embedded in a background of dense breast tissue, with the orientation of the spiculation varied. The key variables involved in each trial included the orientation of the spiculation, contrast level of the spiculation and the CLAHE settings applied to the image. Combining the 10 CLAHE conditions, 4 contrast levels and 4 orientations gave 160 combinations. The trials were constructed by pairing 160 combinations of key variables with 40 backgrounds. Twenty student observers were asked to detect the orientation of the spiculation in the image. There was a statistically significant improvement in detection performance for spiculations with CLAHE over unenhanced images when the region size was set at 32 with a clip level of 2, and when the region size was set at 32 with a clip level of 4. The selected CLAHE settings should be tested in the clinic with digital mammograms to determine whether detection of spiculations associated with masses detected at mammography can be improved

Effectiveness of earlier antenatal screening for sickle cell disease and thalassaemia in primary care: cluster randomised trial

Objective To evaluate the effectiveness of offering antenatal screening for sickle cell disease and thalassaemia in primary care as a way of facilitating earlier uptake of screening

Assembling a high-precision abundance catalogue of solar twins in GALAH for phylogenetic studies

© 2024 The Author(s). Published by Oxford University Press on behalf of Royal Astronomical Society. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/Stellar chemical abundances have proved themselves a key source of information for understanding the evolution of the Milky Way, and the scale of major stellar surveys such as GALAH have massively increased the amount of chemical data available. However, progress is hampered by the level of precision in chemical abundance data as well as the visualization methods for comparing the multidimensional outputs of chemical evolution models to stellar abundance data. Machine learning methods have greatly improved the former; while the application of tree-building or phylogenetic methods borrowed from biology are beginning to show promise with the latter. Here, we analyse a sample of GALAH solar twins to address these issues. We apply The Cannon algorithm to generate a catalogue of about 40 000 solar twins with 14 high precision abundances which we use to perform a phylogenetic analysis on a selection of stars that have two different ranges of eccentricities. From our analyses, we are able to find a group with mostly stars on circular orbits and some old stars with eccentric orbits whose age–[Y/Mg] relation agrees remarkably well with the chemical clocks published by previous high precision abundance studies. Our results show the power of combining survey data with machine learning and phylogenetics to reconstruct the history of the Milky Way.Peer reviewe