1,240 research outputs found

    Hepatitis B virus prevalence in two institutions for the mentally handicapped

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    A comparative study of the prevalence of hepatitis B virus infection in two institutions for the mentally handicapped was carried out between April and November 1989 and April and August 1991. The institutions were situated within 10 km of each other in north-eastern Johannesburg. One institution had a significantly higher prevalence of virus markers, 68% (139 of 203) compared with 23% (40 of 176), was in poorer condition and had more severely handicapped residents with more aggressive behaviour. However, the most important difference between the two institutions was that residents at the higher-prevalence institution were admitted at a considerably younger age. Younger individuals appear to be more susceptible to infection and are more likely to develop persistent infection, thus contributing to a greater pool of infection in the institution

    Primary and secondary infection with human parvovirus B19 in pregnant women in South Africa

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    A study of human parvovirus B19 infection in 1 967 pregnant women of all races in Johannesburg revealed an overall prevalence of 24,9% for IgG antibodies and 3,3% for IgM antibodies. Of the 64 IgM-positive sera indicating active infection, 62 were resistant to urea denaturation. No differences in the prevalence of IgG antibodies between population groups were observed, but active infections, as demonstrated by IgM antibodies, were significantly more prevalent in black than in white, coloured or Asian mothers

    Neural correlates of the behavioral-autonomic interaction response to potentially threatening stimuli

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    Subjective assessment of emotional valence is typically associated with both brain activity and autonomic arousal. Accurately assessing emotional salience is particularly important when perceiving threat. We sought to characterize the neural correlates of the interaction between behavioral and autonomic responses to potentially threatening visual and auditory stimuli. Twenty-five healthy male subjects underwent fMRI scanning whilst skin conductance responses (SCR) were recorded. One hundred and eighty pictures, sentences, and sounds were assessed as “harmless” or “threatening.” Individuals’ stimulus-locked, phasic SCRs and trial-by-trial behavioral assessments were entered as regressors into a flexible factorial design to establish their separate autonomic and behavioral neural correlates, and convolved to examine psycho-autonomic interaction (PAI) effects. Across all stimuli, “threatening,” compared with “harmless” behavioral assessments were associated with mainly frontal and precuneus activation with specific within-modality activations including bilateral parahippocampal gyri (pictures), bilateral anterior cingulate cortex (ACC) and frontal pole (sentences), and right Heschl’s gyrus and bilateral temporal gyri (sounds). Across stimulus modalities SCRs were associated with activation of parieto-occipito-thalamic regions, an activation pattern which was largely replicated within-modality. In contrast, PAI analyses revealed modality-specific activations including right fusiform/parahippocampal gyrus (pictures), right insula (sentences), and mid-cingulate gyrus (sounds). Phasic SCR activity was positively correlated with an individual’s propensity to assess stimuli as “threatening.” SCRs may modulate cognitive assessments on a “harmless–threatening” dimension, thereby modulating affective tone and hence behavior

    Is antenatal screening for rubella and cytomegalovirus justified?

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    Altogether 2 250 asymptomatic pregnant women attending an antenatal clinic were investigated for serological evidence of past exposure to rubella and cytomegalovirus (CMV) as well as for active primary infection or reinfection/ reactivation. Only 7 (0,3%) active rubella infections were diagnosed, none of them primary. Similarly, out of 132 patients with active CMV, only 5 primary infections (3,8%) were diagnosed; the vast majority 127 (96%)- had reactivation infections. No congenital rubella infections were detected, while the transplacental transmission rate for CMV was 6,4%. None of the infants followed up was clinically affected at birth or at 6 months. No racial differences in seroprevalences for CMV or rubella immunoglobulin were observed, but immunoglobulin antibody prevalence to CMV was significantly lower in the white group. From this study there appeared to be no indication for routine antenatal screening for CMV in asymptomatic mothers

    Negative Kaons in Dense Baryonic Matter

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    Kaon polarization operator in dense baryonic matter of arbitrary isotopic composition is calculated including s- and p-wave kaon-baryon interactions. The regular part of the polarization operator is extracted from the realistic kaon-nucleon interaction based on the chiral and 1/N_c expansion. Contributions of the Lambda(1116), Sigma(1195), Sigma*(1385) resonances are taken explicitly into account in the pole and regular terms with inclusion of mean-field potentials. The baryon-baryon correlations are incorporated and fluctuation contributions are estimated. Results are applied for K- in neutron star matter. Within our model a second-order phase transition to the s-wave K- condensate state occurs at rho_c \gsim 4 \rho_0 once the baryon-baryon correlations are included. We show that the second-order phase transition to the p-wave K−K^- condensate state may occur at densities ρc∌3Ă·5ρ0\rho_c \sim 3\div 5 \rho_0 in dependence on the parameter choice. We demonstrate that a first-order phase transition to a proton-enriched (approximately isospin-symmetric) nucleon matter with a p-wave K- condensate can occur at smaller densities, \rho\lsim 2 \rho_0. The transition is accompanied by the suppression of hyperon concentrations.Comment: 41 pages, 24 figures, revtex4 styl

    Action research in physical education: focusing beyond myself through cooperative learning

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    This paper reports on the pedagogical changes that I experienced as a teacher engaged in an action research project in which I designed and implemented an indirect, developmentally appropriate and child‐centred approach to my teaching. There have been repeated calls to expunge – or at least rationalise – the use of traditional, teacher‐led practice in physical education. Yet despite the advocacy of many leading academics there is little evidence that such a change of approach is occurring. In my role as teacher‐as‐researcher I sought to implement a new pedagogical approach, in the form of cooperative learning, and bring about a positive change in the form of enhanced pupil learning. Data collection included a reflective journal, post‐teaching reflective analysis, pupil questionnaires, student interviews, document analysis, and non‐participant observations. The research team analysed the data using inductive analysis and constant comparison. Six themes emerged from the data: teaching and learning, reflections on cooperation, performance, time, teacher change, and social interaction. The paper argues that cooperative learning allowed me to place social and academic learning goals on an even footing, which in turn placed a focus on pupils’ understanding and improvement of skills in athletics alongside their interpersonal development

    Resonant transmission through an open quantum dot

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    We have measured the low-temperature transport properties of a quantum dot formed in a one-dimensional channel. In zero magnetic field this device shows quantized ballistic conductance plateaus with resonant tunneling peaks in each transition region between plateaus. Studies of this structure as a function of applied perpendicular magnetic field and source-drain bias indicate that resonant structure deriving from tightly bound states is split by Coulomb charging at zero magnetic field.Comment: To be published in Phys. Rev. B (1997). 8 LaTex pages with 5 figure
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