Force of Beauty or Object of Desire? The Priming Effects of Makeup Video Advertisements on Self-Objectification in College Women

Women are too often valued for their beauty and have shifted their focus from character to body improvement (Brumberg, 1998). Objectification theory (Frederickson & Roberts, 1997) posits that sexual objectification socializes females to evaluate themselves based on looks. Self-objectification is the attempt to control this external perception by monitoring one’s physical appearance. Women are more likely to think “How do I look?” than “What am I capable of?” The priming effects of positive and negative body-focused makeup advertisements on college-aged women’s level of self-objectification were examined in two separate studies. In study one, 87 participants viewing positive vs. negative advertisements reported more traits and abilities; this was especially true for high self-objectifiers. Participants viewing positive advertisements reported more positive emotions, suggesting the salutary role that positive messaging may play. Results were replicated in study two, with 172 participants who viewed positive vs. negative advertisements reporting significantly fewer body shape statements, more trait and abilities, as well as more physical competence statements. In addition, individuals who viewed advertisements with non-objectifying content responded with a significantly greater number of positively valenced statements and significantly fewer negative statements about themselves in comparison to women who viewed objectifying advertisements. These results suggest that marketers should eschew advertising that sexually objectifies women and promotes unattainable beauty goals. Future research should evaluate cumulative and long-term effects of advertisement and examine whether exposure that leads to lower levels of objectification also minimizes negative consequences associated with objectifying media influences (e.g., body shame, depression, eating disorder)

Intragenic alternative splicing coordination is essential for Caenorhabditis elegans slo-1 gene function

Alternative splicing is critical for diversifying eukaryotic proteomes, but the rules governing and coordinating splicing events among multiple alternate splice sites within individual genes are not well understood. We developed a quantitative PCR-based strategy to quantify the expression of the 12 transcripts encoded by the Caenorhabditis elegans slo-1 gene, containing three alternate splice sites. Using conditional probability-based models, we show that splicing events are coordinated across these sites. Further, we identify a point mutation in an intron adjacent to one alternate splice site that disrupts alternative splicing at all three sites. This mutation leads to aberrant synaptic transmission at the neuromuscular junction. In a genomic survey, we found that a UAAAUC element disrupted by this mutation is enriched in introns flanking alternate exons in genes with multiple alternate splice sites. These results establish that proper coordination of intragenic alternative splicing is essential for normal physiology of slo-1 in vivo and identify putative specialized cis-regulatory elements that regulate the coordination of intragenic alternative splicing

Polarization Requirements for Ensemble Implementations of Quantum Algorithms with a Single Bit Output

We compare the failure probabilities of ensemble implementations of quantum algorithms which use pseudo-pure initial states, quantified by their polarization, to those of competing classical probabilistic algorithms. Specifically we consider a class algorithms which require only one bit to output the solution to problems. For large ensemble sizes, we present a general scheme to determine a critical polarization beneath which the quantum algorithm fails with greater probability than its classical competitor. We apply this to the Deutsch-Jozsa algorithm and show that the critical polarization is 86.6%.Comment: 11 pages, 3 figure

The Parallel Worm Tracker: A Platform for Measuring Average Speed and Drug-Induced Paralysis in Nematodes

Background Caenorhabditis elegans locomotion is a simple behavior that has been widely used to dissect genetic components of behavior, synaptic transmission, and muscle function. Many of the paradigms that have been created to study C. elegans locomotion rely on qualitative experimenter observation. Here we report the implementation of an automated tracking system developed to quantify the locomotion of multiple individual worms in parallel. Methodology/Principal Findings Our tracking system generates a consistent measurement of locomotion that allows direct comparison of results across experiments and experimenters and provides a standard method to share data between laboratories. The tracker utilizes a video camera attached to a zoom lens and a software package implemented in MATLAB®. We demonstrate several proof-of-principle applications for the tracker including measuring speed in the absence and presence of food and in the presence of serotonin. We further use the tracker to automatically quantify the time course of paralysis of worms exposed to aldicarb and levamisole and show that tracker performance compares favorably to data generated using a hand-scored metric. Conclusions/Signficance Although this is not the first automated tracking system developed to measure C. elegans locomotion, our tracking software package is freely available and provides a simple interface that includes tools for rapid data collection and analysis. By contrast with other tools, it is not dependent on a specific set of hardware. We propose that the tracker may be used for a broad range of additional worm locomotion applications including genetic and chemical screening

The Dystrophin Complex Controls BK Channel Localization and Muscle Activity in Caenorhabditis elegans

Genetic defects in the dystrophin-associated protein complex (DAPC) are responsible for a variety of pathological conditions including muscular dystrophy, cardiomyopathy, and vasospasm. Conserved DAPC components from humans to Caenorhabditis elegans suggest a similar molecular function. C. elegans DAPC mutants exhibit a unique locomotory deficit resulting from prolonged muscle excitation and contraction. Here we show that the C. elegans DAPC is essential for proper localization of SLO-1, the large conductance, voltage-, and calcium-dependent potassium (BK) channel, which conducts a major outward rectifying current in muscle under the normal physiological condition. Through analysis of mutants with the same phenotype as the DAPC mutants, we identified the novel islo-1 gene that encodes a protein with two predicted transmembrane domains. We demonstrate that ISLO-1 acts as a novel adapter molecule that links the DAPC to SLO-1 in muscle. We show that a defect in either the DAPC or ISLO-1 disrupts normal SLO-1 localization in muscle. Consistent with observations that SLO-1 requires a high calcium concentration for full activation, we find that SLO-1 is localized near L-type calcium channels in muscle, thereby providing a mechanism coupling calcium influx with the outward rectifying current. Our results indicate that the DAPC modulates muscle excitability by localizing the SLO-1 channel to calcium-rich regions of C. elegans muscle

Pediatric Phantom Dosimetry of Kodak 9000 Cone-beam Computed Tomography

Purpose: The purpose of the study was to evaluate the radiation dose of the Kodak 9000 cone-beam computed tomography (CBCT) device for different anatomical areas using a pediatric phantom. Methods: Absorbed doses resulting from maxillary and mandibular region three by five cm CBCT volumes of an anthropomorphic 10-year-old child phantom were acquired using optical stimulated dosimetry. Equivalent doses were calculated for radiosensitive tissues in the head and neck area, and effective dose for maxillary and mandibular examinations were calculated following the 2007 recommendations of the International Commission on Radiological Protection (ICRP). Results: Of the mandibular scans, the salivary glands had the highest equivalent dose (1,598 microsieverts [μSv]), followed by oral mucosa (1,263 μSv), extrathoracic airway (pharynx, larynx, and trachea; 859 μSv), and thyroid gland (578 μSv). For the maxilla, the salivary glands had the highest equivalent dose (1,847 μSv), followed closely by oral mucosa (1,673 μSv), followed by the extrathoracic airway (pharynx, larynx, and trachea; 1,011 μSv) and lens of the eye (202 μSv). Conclusion: Compared to previous research of the Kodak 9000, completed with the adult phantom, a child receives one to three times more radiation for mandibular scans and two to 10 times more radiation for maxillary scans

Effects of increasing soybean hulls in finishing diets with wet or modified distillers grains plus solubles on performance and carcass characteristics of beef steers

Two experiments evaluated feeding soybean hulls (SBH) in finishing diets that contain distillers grains plus solubles on performance and carcass characteristics. Dietary concentrations of SBH were 0, 12.5, 25, and 37.5% of diet DM. In Exp. 1, 167 crossbred yearling steers (395 ± 22 kg of BW) were fed for 117 d in a randomized block design in which pelleted SBH replaced dry-rolled corn. All diets contained 25% modified distillers grains plus solubles, 15% corn silage, and 5% liquid supplement. As SBH concentration increased, DMI decreased linearly (P = 0.04). Gain and G:F decreased linearly (P \u3c 0.01) in response to increasing concentrations of SBH, which decreased relative energy value from 91 to 79% of corn. Hot carcass weight linearly decreased (P \u3c 0.01) by 24 kg as SBH increased. In Exp. 2, a randomized block design used 160 backgrounded steer calves (363 ± 16 kg of BW) in a 138-d finishing study with 0, 12.5, 25, or 37.5% SBH in the meal form. Basal ingredients consisted of a 1:1 ratio of high-moisture corn and dry-rolled corn, 40% wet distillers grains plus solubles, 8% sorghum silage, and 4% dry meal supplement. There was a tendency (P = 0.12) for a quadratic increase in ADG and G:F as dietary SBH increased, with numerically greatest ADG and G:F with 12.5% SBH. Feeding 12.5 to 25% SBH with 40% wet distillers grains plus solubles (Exp. 2) had little effect on performance but decreased ADG and G:F in diets with 25% modified distillers grains plus solubles (Exp. 1)

Validity and Value of Wave Energy Generation as Blackout Risk Mitigation for the Central Oregon Coast

Energy security is a vital but often unmet requirement for community resiliency. Electricity availability is essential to the functioning of the economy, individual households, and the collective essential services that provide health, safety, and the basic human needs to sustain life. Coastal communities in Oregon face special vulnerability because they are almost entirely dependent on outside sources of electricity generation routed via a limited number of transmission lines over a coastal mountain range, where they are prone to damage. When these lines fail, as has occurred in past storms, the coast can be electrically stranded from the regional grid network and large swaths of coastal communities are without power. This vulnerability raises a question whether this risk to coastal community energy resilience could be mitigated through utilization of a local and abundant renewable energy source: ocean wave energy. This transdisciplinary report assesses key technical, natural system, socio-economic, and regulatory considerations surrounding the validity and value of Wave Energy Converters (WECs) as an emergency power generation resource for the example community of Newport, Oregon. The work was performed by a collaborative, multi-disciplinary team of graduate researchers as part of the National Science Foundation National Research Traineeship in Risk and Uncertainty Quantification and Communication in Marine Sciences at Oregon State University. This report imagines a scenario in which an event such as a winter storm causes a regional transmission line outage in the example community of Newport, Oregon for a hypothetical duration of two weeks. We propose a system of rapidly deployed WECs connected to the local electrical grid to allow conversion of the Central Lincoln PUD service area into an “islanded microgrid” that can provide locally for the community’s critical infrastructure services. In this context, the goal of having an islanded microgrid is to be able to use local sources to supply the community’s electrical needs. We determine that marine renewable energy (MRE) may be a valid risk mitigation alternative from a technical and regulatory standpoint with the proper consideration of grid integration needs and support for emergency MRE options on a policy level. Based on the findings in this report, it appears that the temporary emergency WEC use case would be economically infeasible given the estimated power demand for critical services and the generation capabilities of currently available WEC devices. However, our research shows that there are significant gaps in knowledge regarding how we value critical services in a long emergency, and advancements in this field may change the value proposition of an emergency WEC use case. Additionally, advancements in wave energy technology or emergency power demand management may reduce the total size requirements for an emergency WEC array, or the logistical ability to deploy the WEC system, changing the feasibility and cost of the system in the future. Moreover, there is additional uncertainty regarding the recurrence interval of an outage of sufficient scale to warrant investment

Investigating the physical properties of transiting hot Jupiters with the 1.5-m Kuiper Telescope

We present new photometric data of 11 hot Jupiter transiting exoplanets (CoRoT-12b, HAT-P-5b, HAT-P-12b, HAT-P-33b, HAT-P-37b, WASP-2b, WASP-24b, WASP-60b, WASP-80b, WASP-103b, XO-3b) in order to update their planetary parameters and to constrain information about their atmospheres. These observations of CoRoT-12b, HAT-P-37b and WASP-60b are the first follow-up data since their discovery. Additionally, the first near-UV transits of WASP-80b and WASP-103b are presented. We compare the results of our analysis with previous work to search for transit timing variations (TTVs) and a wavelength dependence in the transit depth. TTVs may be evidence of a third body in the system and variations in planetary radius with wavelength can help constrain the properties of the exoplanet's atmosphere. For WASP-103b and XO-3b, we find a possible variation in the transit depths that may be evidence of scattering in their atmospheres. The B-band transit depth of HAT-P-37b is found to be smaller than its near-IR transit depth and such a variation may indicate TiO/VO absorption. These variations are detected from 2-4.6$\sigma$, so follow-up observations are needed to confirm these results. Additionally, a flat spectrum across optical wavelengths is found for 5 of the planets (HAT-P-5b, HAT-P-12b, WASP-2b, WASP-24b, WASP-80b), suggestive that clouds may be present in their atmospheres. We calculate a refined orbital period and ephemeris for all the targets, which will help with future observations. No TTVs are seen in our analysis with the exception of WASP-80b and follow-up observations are needed to confirm this possible detection.Comment: 18 pages, 7 figures, 9 Tables. Light Curves available online. Accepted to MNRAS (2017 August 25