1,135 research outputs found

    With This Ring

    Get PDF
    Illustration of wedding band with flower in center of ringhttps://scholarsjunction.msstate.edu/cht-sheet-music/6833/thumbnail.jp

    “Putting History to Work in the World”: the National Council on Public History

    Get PDF
    poster abstractFor twenty-four years the National Council on Public History (NCPH) has been based in the Department of History as an external agency of IUPUI. A non-profit scholarly and professional group, with members across North America and in several other countries, NCPH serves public historians and promotes the burgeoning field of public history—which itself is an important form of civic engagement and translational research. What is public history? It describes the many and diverse ways in which history is put to work in the world. In this sense, it is history that is applied to real-world issues. While the theory and methodology of public history remain firmly in the discipline of history, and all good public history rests on sound scholarship, public historians routinely engage in collaborative work, conceptualize projects with a non-scholarly audience in mind, and typically frame their questions and evidence with the participation of these audiences. Some have shorthanded the definition of public history as “history outside of the classroom,” but increasingly the field or profession of public history moves back and forth between classrooms and the world beyond, involving historical consultants, museum professionals, government historians, archivists, oral historians, cultural resource managers, curators, film and media producers, historical interpreters, historic preservationists, policy advisers, local historians, and community activists, among many other job descriptions. The national executive office of NCPH collaborates with the Department of History’s Public History Program, which is one of the best and oldest of the 138 MA programs in the United States. A half-time graduate student intern from the IUPUI Public History Program provides crucial assistance, and the executive director of NCPH, a faculty member, works with the Department’s Public History Program director and co-director on a range of projects. Recently these have included or will include chairing the 600-person NCPH conference in Nashville in 2016 and hosting it in Indianapolis in 2017, creating Careers in History symposia for undergraduates, and a phone app project providing historical tours of Indianapolis created with community partners and local public history institutions. The latter will become a statewide effort in conjunction with the Indiana’s 2016 Bicentennial. NCPH helped launch a sister group, the International Federation for Public History, publishes the flagship peer-reviewed journal in the field, The Public Historian, issues best practice documents, organized the jointly produced “Tenure, Promotion, and the Publicly Engaged Academic Historian” report, maintains numerous digital and other venues for scholarly communication, recognizes cutting edge work with its annual awards program, and fosters many other ways of making the past useful in the present and to encouraging collaboration between historians and their public

    An Analysis of Strategic Treatment Interruptions During Imatinib Treatment of Chronic Myelogenous Leukemia with Imatinib-Resistant Mutations

    Get PDF
    Chronic myelogenous leukemia (CML) is a cancer of the white blood cells that results from increased and uncontrolled growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood. The most common form of treatment for CML is imatinib, a tyrosine kinase inhibitor. Although imatinib is an effective treatment for CML and most patients treated with imatinib do attain some form of remission, imatinib does not completely eradicate all leukemia cells, and if treatment is stopped, all patients eventually relapse (Cortes, 2005). In Kim (2008), the authors developed a mathematical model for the dynamics of CML under imatinib treatment that incorporates the anti-leukemia immune response, and in Paquin (2011), the authors used this mathematical model to study strategic treatment interruptions as a potential therapeutic strategy for CML patients. Although the authors presented the results of several numerical simulations in Paquin (2011), the studies in that work did not include the possibility of imatinib-resistant mutations or an initial population of imatinib-resistant leukemia cells. As resistance is a significant consideration in any drug treatment, it is important to study the efficacy of the strategic treatment interruption plan in the presence of imatinib resistance. In this work, we modify the delay differential equations model of Kim (2008), Paquin (2011) to include the possibility of imatinib resistance, and we analyze strategic treatment interruptions as a potential therapeutic tool in the case of patients with imatinib-resistance leukemia cells

    The Terry Score

    Get PDF
    This article is part of the District of Columbia Survey

    The Terry Score

    Get PDF
    This article is part of the District of Columbia Survey

    Positive Surgical Margins in the 10 Most Common Solid Cancers.

    Get PDF
    A positive surgical margin (PSM) following cancer resection oftentimes necessitates adjuvant treatments and carries significant financial and prognostic implications. We sought to compare PSM rates for the ten most common solid cancers in the United States, and to assess trends over time. Over 10 million patients were identified in the National Cancer Data Base from 1998-2012, and 6.5 million had surgical margin data. PSM rates were compared between two time periods, 1998-2002 and 2008-2012. PSM was positively correlated with tumor category and grade. Ovarian and prostate cancers had the highest PSM prevalence in women and men, respectively. The highest PSM rates for cancers affecting both genders were seen for oral cavity tumors. PSM rates for breast cancer and lung and bronchus cancer in both men and women declined over the study period. PSM increases were seen for bladder, colon and rectum, and kidney and renal pelvis cancers. This large-scale analysis appraises the magnitude of PSM in the United States in order to focus future efforts on improving oncologic surgical care with the goal of optimizing value and improving patient outcomes

    Factors associated with long-term mortality for stroke unit patients in Latvia

    Get PDF
    Publisher Copyright: © 2018 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.Aim: The aim of this study was to evaluate how pre-stroke risk factors, neurological symptoms, and the level of disability shortly after stroke are associated with poststroke mortality during a 7-year period after stroke, for persons treated in a stroke unit. Methods: The data of 231 patients were included in the study. Patients who were treated in the stroke unit at the Riga East University Hospital between February 1, 2009, and July 20, 2009, were included in this study. Three stepwise Cox proportional hazard analyses were performed to analyze mortality in the 7 years following stroke. Pre-stroke risk factors (type of stroke, arterial hypertension, diabetes mellitus, atrial fibrillation, smoking, alcohol abuse, obesity, recurrent stroke, age, gender), neurological symptoms (motor deficit, sensory disturbance, aphasia, poststroke urinary incontinence (PSUI), mental status), and limitations of activity (feeding, bathing, grooming, dressing, toilet use, transfers, mobility, stairs) were evaluated as factors associated with mortality after stroke. Results: A total of 145 (62.8%) patients died during the study period. The final model for each group of factors included only one of the factors used for the analysis. Patients who had alcohol abuse were 40% more likely to die earlier. The hazard for those with PSUI is 1.72 times higher than those without PSUI. The independence in grooming showed a 39% lower likelihood of dying earlier. Conclusion: Alcohol abuse as a pre-stroke risk factor, poststroke urinary incontinence as a neurological symptom, and dependence in grooming as a factor of disability were associated with earlier mortality in the first seven years after stroke.publishersversionPeer reviewe
    corecore