First Records of the White People Shoot Border, Eucosma Gloriola (Lepidoptera: Olethreutidae) in Michigan

Excerpt: During late June and early July, 1965, it was apparent that plantations of Scotch and Austrian pines in various Michigan counties were being damaged by lepidopterous larvae mining in the pith of newly developed lateral and terminal branches. Infested samples were examined by Dr. William Wallner, Department of Entomology, Michigan State University, and an attempt was made to rear the extracted larvae. Although as many as two larvae were present in some of the shoots, none survived and no adult moths were secured. A series of larvae was preserved for future study

Moth Species New to Michigan

This is a compilation of moth species previously unrecorded from Michigan. Moore\u27s (1955) publication has been critically examined necessitating some specific changes. All questionable material has been determined by present day specialists in their particular fields. The McDunnough (1938) checklist is followed in the arrangement of the new data together with most of the recent changes in nomenclature as presented by Forbes (1948, 1954, 1960), Hardwick (1970), Hodges (1971), and Covell (1970, 1971). With the advent of more sophisticated collecting equipment and the easier access to Michigan\u27s Upper Peninsula a total of 154 species has been added. Many institutional and private collections have been examined including the large collection at Michigan State University which was not considered in the Moore publication

The Genus Phragmatobia in North America, with the Description of a New Species (Lepidoptera: Arctiidae)

Excerpt: This paper, based on the examination of 1,879 specimens, serves to resolve the taxonomic problems involving the three North American species of Phragmatobia. The genus Phragmatobia, the ruby tiger moths, has had a checkered history since it was described by Stephens in 1829 (type, by monotypy, Noctua j\u27uliginosa Linnaeus, 1758). Although many species have been described in or transferred to this genus, in both the Old and New Worlds, most of them have been removed to other genera. By 1902 Dyar recognized only two North American species, a status since then unchanged (McDunnough, 1938; Forbes, 1960). Despite the recent stability of the names, there has been much confusion as to which names to apply to particular specimens. This problem is resolved below, with the description of a third North American species, long confused with the two named species

Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model.

The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice engrafted with the human t(4;11) ALL SEM cell line. SEM cells were injected into the tail vein and engraftment was monitored by flow cytometry. Once engraftment was observed, mice were injected intraperitoneally with resveratrol (10 mg/kg body weight) dissolved in dimethylsulfoxide (DMSO) or DMSO alone (control) every other day, or vincristine (0.5 mg/kg body weight) 3 times per week for 4 weeks (n=16 per group). Comparisons of the percent of human leukemia cells in blood and survival curves showed resveratrol did not inhibit progression of the disease. Liquid chromatography-tandem mass spectrometry analyses of mouse sera showed resveratrol was rapidly metabolized to glucuronidated and sulfated forms 1 h post-injection, with low to no resveratrol or metabolites observed in sera by 24-48 h. These data indicate that in contrast to findings in in vitro models, parenterally administered resveratrol does not have potential as a preventive agent against high risk t(4;11) ALL

20S human proteasomes bind with a specific orientation to lipid monolayers in vitro

Abstract20S Proteasomes are non-lysosomal, high molecular weight proteinases implicated in the degradation of misfolded proteins and several short-lived regulatory proteins. They have a well established role, as the core of the 26S proteasome complex, in the ubiquitin-dependent proteolytic pathway and in antigen processing. While correctly folded proteins are not degraded by the 20S proteasome, unfolding, for example by oxidation, may render them degradable. The 20S proteasome is a 700-kDa cylindrical particle, composed of 14 subunits of molecular masses 20–35 kDa. There is evidence that 20S proteasomes are in close proximity to or associate with the endoplasmic reticulum and nuclear and plasma membranes in vivo. To better understand the lipid association of 20S proteasomes in vitro, we used a lipid monolayer system as a simple model system for biological membranes. The structure and orientation of the monolayer lipid bound 20S proteasomes has been determined by electron microscopy. 20S proteasomes associated in an ‘end-on’ configuration specifically on PI lipid monolayers forming large arrays, with their channels opposite the lipid headgroups. On ER and Golgi lipid films 20S proteasones were oriented in the same way as on the PI lipid film but were monodisperse. Protein molecules were randomly oriented in the presence of PA, PG, PS, PC and mitochondrial lipid monolayers. We show that 20S proteasomes bind to phospholipids in vitro in a preferred orientation which places the proteasome channel perpendicular to the membrane

Method for repairing cracks in structures

A first material with a known maximum temperature of operation is coated with a second material on at least one surface of the first material. The coating has a melting temperature that is greater than the maximum temperature of operation of the first material. The coating is heated to its melting temperature until the coating flows into any cracks in the first material's surface

The close limit from a null point of view: the advanced solution

We present a characteristic algorithm for computing the perturbation of a Schwarzschild spacetime by means of solving the Teukolsky equation. We implement the algorithm as a characteristic evolution code and apply it to compute the advanced solution to a black hole collision in the close approximation. The code successfully tracks the initial burst and quasinormal decay of a black hole perturbation through 10 orders of magnitude and tracks the final power law decay through an additional 6 orders of magnitude. Determination of the advanced solution, in which ingoing radiation is absorbed by the black hole but no outgoing radiation is emitted, is the first stage of a two stage approach to determining the retarded solution, which provides the close approximation waveform with the physically appropriate boundary condition of no ingoing radiation.Comment: Revised version, published in Phys. Rev. D, 34 pages, 13 figures, RevTe