751 research outputs found
TESS Observations of Kepler systems with Transit Timing Variations
We identify targets in the Kepler field that may be characterized by transit
timing variations (TTVs) and are detectable by the Transiting Exoplanet Survey
Satellite (TESS). Despite the reduced signal-to-noise ratio of TESS transits
compared to Kepler, we recover 48 transits from 13 systems in Sectors 14, 15,
26, 40 and 41. We find strong evidence of a nontransiting perturber orbiting
Kepler-396 (KOI-2672) and explore two possible cases of a third planet in that
system that could explain the measured transit times. We update the ephemerides
and mass constraints where possible at KOI-70 (Kepler-20), KOI-82 (Kepler-102),
KOI-94 (Kepler-89), KOI-137 (Kepler-18), KOI-244 (Kepler-25), KOI-245
(Kepler-37), KOI-282 (Kepler-130), KOI-377 (Kepler-9), KOI-620 (Kepler-51),
KOI-806 (Kepler-30), KOI-1353 (Kepler-289) and KOI-1783 (Kepler-1662).Comment: 26 pages, 9 figure
Properties of the H-alpha-emitting Circumstellar Regions of Be Stars
Long-baseline interferometric observations obtained with the Navy Prototype
Optical Interferometer of the H-alpha-emitting envelopes of the Be stars eta
Tauri and beta Canis Minoris are presented. For compatibility with the
previously published interferometric results in the literature of other Be
stars, circularly symmetric and elliptical Gaussian models were fitted to the
calibrated H-alpha observations. The models are sufficient in characterizing
the angular distribution of the H-alpha-emitting circumstellar material
associated with these Be stars. To study the correlations between the various
model parameters and the stellar properties, the model parameters for eta Tau
and beta CMi were combined with data for other Be stars from the literature.
After accounting for the different distances to the sources and stellar
continuum flux levels, it was possible to study the relationship between the
net H-alpha emission and the physical extent of the H-alpha-emitting
circumstellar region. A clear dependence of the net H-alpha emission on the
linear size of the emitting region is demonstrated and these results are
consistent with an optically thick line emission that is directly proportional
to the effective area of the emitting disk. Within the small sample of stars
considered in this analysis, no clear dependence on the spectral type or
stellar rotation is found, although the results do suggest that hotter stars
might have more extended H-alpha-emitting regions.Comment: 24 pages, 16 figures, accepted for publication in Ap
Validation of Kepler's Multiple Planet Candidates. III: Light Curve Analysis & Announcement of Hundreds of New Multi-planet Systems
The Kepler mission has discovered over 2500 exoplanet candidates in the first
two years of spacecraft data, with approximately 40% of them in candidate
multi-planet systems. The high rate of multiplicity combined with the low rate
of identified false-positives indicates that the multiplanet systems contain
very few false-positive signals due to other systems not gravitationally bound
to the target star (Lissauer, J. J., et al., 2012, ApJ 750, 131). False
positives in the multi- planet systems are identified and removed, leaving
behind a residual population of candidate multi-planet transiting systems
expected to have a false-positive rate less than 1%. We present a sample of 340
planetary systems that contain 851 planets that are validated to substantially
better than the 99% confidence level; the vast majority of these have not been
previously verified as planets. We expect ~2 unidentified false-positives
making our sample of planet very reliable. We present fundamental planetary
properties of our sample based on a comprehensive analysis of Kepler light
curves and ground-based spectroscopy and high-resolution imaging. Since we do
not require spectroscopy or high-resolution imaging for validation, some of our
derived parameters for a planetary system may be systematically incorrect due
to dilution from light due to additional stars in the photometric aperture.
None the less, our result nearly doubles the number of verified exoplanets.Comment: 138 pages, 8 Figures, 5 Tables. Accepted for publications in the
Astrophysical Journa
K2-19b and c are in a 3:2 Commensurability but out of Resonance: A Challenge to Planet Assembly by Convergent Migration
K2-19b and c were among the first planets discovered by NASA's K2 mission and together stand in stark contrast with the physical and orbital properties of the solar system planets. The planets are between the size of Uranus and Saturn at 7.0 ± 0.2 R⊕ and 4.1 ± 0.2 R⊕, respectively, and reside a mere 0.1% outside the nominal 3:2 mean-motion resonance. They represent a different outcome of the planet formation process than the solar system, as well as the vast majority of known exoplanets. We measured the physical and orbital properties of these planets using photometry from K2, Spitzer, and ground-based telescopes, along with radial velocities from Keck/HIRES. Through a joint photodynamical model, we found that the planets have moderate eccentricities of e ≈ 0.20 and well-aligned apsides Δϖ ≈ 0°. The planets occupy a strictly nonresonant configuration: the resonant angles circulate rather than librate. This defies the predictions of standard formation pathways that invoke convergent or divergent migration, both of which predict Δ ≈ 180° and eccentricities of a few percent or less. We measured masses of M_(p,b) = 32.4 ± 1.7 M⊕ and M_(p,c) = 10.8 ± 0.6 M⊕. Our measurements, with 5% fractional uncertainties, are among the most precise of any sub-Jovian exoplanet. Mass and size reflect a planet's core/envelope structure. Despite having a relatively massive core of M_(core) ≈ 15 M⊕, K2-19b is envelope-rich, with an envelope mass fraction of roughly 50%. This planet poses a challenge to standard models of core-nucleated accretion, which predict that cores ≳10 M⊕ will quickly accrete gas and trigger runaway accretion when the envelope mass exceeds that of the core
The Transcriptional Response of Drosophila melanogaster to Infection with the Sigma Virus (Rhabdoviridae)
Bacterial and fungal infections induce a potent immune response in Drosophila melanogaster, but it is unclear whether viral infections induce an antiviral immune response. Using microarrays, we examined the changes in gene expression in Drosophila that occur in response to infection with the sigma virus, a negative-stranded RNA virus (Rhabdoviridae) that occurs in wild populations of D. melanogaster. We detected many changes in gene expression in infected flies, but found no evidence for the activation of the Toll, IMD or Jak-STAT pathways, which control immune responses against bacteria and fungi. We identified a number of functional categories of genes, including serine proteases, ribosomal proteins and chorion proteins that were overrepresented among the differentially expressed genes. We also found that the sigma virus alters the expression of many more genes in males than in females. These data suggest that either Drosophila do not mount an immune response against the sigma virus, or that the immune response is not controlled by known immune pathways. If the latter is true, the genes that we identified as differentially expressed after infection are promising candidates for controlling the host's response to the sigma virus
Population transcriptomics of Drosophila melanogaster females
<p>Abstract</p> <p>Background</p> <p>Variation at the level of gene expression is abundant in natural populations and is thought to contribute to the adaptive divergence of populations and species. Gene expression also differs considerably between males and females. Here we report a microarray analysis of gene expression variation among females of 16 <it>Drosophila </it><it>melanogaster </it>strains derived from natural populations, including eight strains from the putative ancestral range in sub-Saharan Africa and eight strains from Europe. Gene expression variation among males of the same strains was reported previously.</p> <p>Results</p> <p>We detected relatively low levels of expression polymorphism within populations, but much higher expression divergence between populations. A total of 569 genes showed a significant expression difference between the African and European populations at a false discovery rate of 5%. Genes with significant over-expression in Europe included the insecticide resistance gene <it>Cyp6g1</it>, as well as genes involved in proteolysis and olfaction. Genes with functions in carbohydrate metabolism and vision were significantly over-expressed in the African population. There was little overlap between genes expressed differently between populations in females and males.</p> <p>Conclusions</p> <p>Our results suggest that adaptive changes in gene expression have accompanied the out-of-Africa migration of <it>D. melanogaster</it>. Comparison of female and male expression data indicates that the vast majority of genes differing in expression between populations do so in only one sex and suggests that most regulatory adaptation has been sex-specific.</p
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing
molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin
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