4,647 research outputs found
Ionized interstellar froth in irregular galaxies
The warm interstellar medium of galaxies is a complicated place. It is often full of holes, neutral and ionized loops and shells, and diffuse ionized gas. Deep H alpha images of Magellanic-type irregular galaxies also reveal complex spatial structures consisting of loops and filaments in the interstellar gas outside of the boundaries of traditional HII regions. Researchers refer to these ionized structures as froth. Such structures could mark paths over which newly produced heavy elements are dispersed in irregular galaxies, and they could be the signatures of a feedback process related to star formation. In order to investigate the physical nature of the froth, researchers obtained narrow-band images and high and low dispersion spectra from Kitt Peak National Observatory (KPNO) and deep blue-passband plates from the Canada-France-Hawaii Observatory (CFHO)
CARMIL family proteins as multidomain regulators of actin-based motility
CARMILs are large multidomain proteins that regulate the actin-binding activity of capping protein (CP), a major capper of actin filament barbed ends in cells. CARMILs bind directly to CP and induce a conformational change that allosterically decreases but does not abolish its actin-capping activity. The CP-binding domain of CARMIL consists of the CP-interaction (CPI) and CARMIL-specific interaction (CSI) motifs, which are arranged in tandem. Many cellular functions of CARMILs require the interaction with CP; however, a more surprising result is that the cellular function of CP in cells appears to require binding to a CARMIL or another protein with a CPI motif, suggesting that CPI-motif proteins target CP and modulate its actin-capping activity. Vertebrates have three highly conserved genes and expressed isoforms of CARMIL with distinct and overlapping localizations and functions in cells. Various domains of these CARMIL isoforms interact with plasma membranes, vimentin intermediate filaments, SH3-containing class I myosins, the dual-GEF Trio, and other adaptors and signaling molecules. These biochemical properties suggest that CARMILs play a variety of membrane-associated functions related to actin assembly and signaling. CARMIL mutations and variants have been implicated in several human diseases. We focus on roles for CARMILs in signaling in addition to their function as regulators of CP and actin. </jats:p
Measuring star formation rates in blue galaxies
The problems associated with measurements of star formation rates in galaxies are briefly reviewed, and specific models are presented for determinations of current star formation rates from H alpha and Far Infrared (FIR) luminosities. The models are applied to a sample of optically blue irregular galaxies, and the results are discussed in terms of star forming histories. It appears likely that typical irregular galaxies are forming stars at nearly constant rates, although a few examples of systems with enhanced star forming activity are found among HII regions and luminous irregular galaxies
A comparison of Olpidium isolates from a range of host plants using internal transcribed spacer sequence analysis and host range studies
Olpidium brassicae is a ubiquitous obligate root-infecting fungal pathogen. It is an important vector of a wide range of plant viruses. Olpidium isolates that infected brassica plants did not infect lettuce plants and vice-versa. Host range tests, PCR amplification and sequencing of the internal transcribed spacer (ITS) and 5.8S regions of 25 Olpidium isolates from brassica, carrot, cucumber and lettuce originating from four continents revealed differences between isolates. Based on their ability to infect lettuce and brassicas and the differences between their ITS1, 5.8S and ITS2 regions they could be separated into a number of distinct groups. Comparisons with other published sequences revealed two distinct genetic groups of brassica-infecting isolates, two distinct groups of lettuce-infecting isolates, one of which contained a carrot-infecting isolate and a distinct group comprising a cucumber-infecting isolate and a melon-infecting isolate. The possibility of the isolates belonging to three distinct species is discussed
Shop Rotordynamic Testing - Options, Objectives, Benefits and Practices
TutorialUnderstanding the lateral rotordynamic behavior is critical in determining the reliability/operability of rotating equipment. Whether examining a centrifugal pump or compressor, steam or gas turbine, motor or generator, rotating machinery share the same need to accurately predict and measure dynamic behavior. Industrial specifications determining fit for purpose rely on the accuracy of rotordynamic predictions where direct measurement is impractical or otherwise impossible in an industrial setting. Testing to confirm rotordynamic prediction and behavior provides both the purchaser and vendor the confidence that the design will meet project expectations. Rotordynamic shop testing has several options available to the project during acceptance tests at the vendor’s shop. These options include mechanical run, string and full load/Type 1 testing as well as verification testing to validate unbalance response and stability predictions. Such testing has numerous advantages; the most important being the avoidance of production disruptions involved with testing at the job site. Each test option has associated costs as well as limitations as to what lateral vibration characteristics are revealed. Understanding these factors is vital to efficiently mitigate the risks associated with the purchased equipment. Applying best practices and an understanding of the industrial (API) test requirements are needed to derive the maximum benefit of each test option. The best practices not only involve the test procedure but also the associated analytical methods used to post process the measurement information. Whether performing a simple mechanical run test or more complex stability verification during ASME Type I testing, ensuring that a logical, repeatable and proven methodology is followed produces reliable evidence to confirm the rotordynamic model and lateral vibration performance. The rationale behind the API test requirements provides an understanding of why that test is being performed and its correct application to the dynamic behavior. Test options can be separated into two categories; tests that reveal portions of the dynamic behavior of the equipment to specific operating conditions and those used to verify the analytical predictions of that behavior. API mechanical, string and Type I (or full load) tests reveal the rotordynamic behavior of the equipment to a given set of conditions. These are used specifically to determine acceptability of the design. Unbalance and stability verification testing is used to confirm (or provide confidence in) the rotordynamic model. Confidence in the model permits extrapolation of the design (vendor) and operation (purchaser) beyond the machine’s asbuilt and specific shop test conditions
Distribution and incidence of viruses in Irish seed potato crops
peer-reviewedVirus diseases are of key importance in potato production and in particular for the production of disease-free potato seed. However, there is little known about the frequency and distribution of potato virus diseases in Ireland. Despite a large number of samples being tested each year, the data has never been collated either within or across years. Information from all known potato virus testing carried out in the years 2006–2012 by the Department of Agriculture Food and Marine was collated to give an indication of the distribution and incidence of potato virus in Ireland. It was found that there was significant variation between regions, varieties, years and seed classes. A definition of daily weather data suitable for aphid flight was developed, which accounted for a significant proportion of the variation in virus incidence between years. This use of weather data to predict virus risk could be developed to form the basis of an integrated pest management approach for aphid control in Irish potato crops
Flight Measurements to Determine Effect of a Spring-Loaded Tab on Longitudinal Stability of an Airplane
In conjunction with a program of research on the general problem of stability of airplanes in the climbing condition, tests have been made of a spring-loaded tb which. is referred to as a ?springy tab,? installed on the elevator of a low-wing scout bomber. The tab was arranged to deflect upward with decrease in speed which caused an increase in the pull force required to trim at low speeds and thereby increased the stick-free static longitudinal stability of the airplane. It was found that the springy tab would increase the stick-free stability in all flight conditions, would reduce the danger of inadvertent stalling because of the definite pull force required to stall the airplane with power on, would reduce the effect of center-of-gravity position on stick-free static stability, and would have little effect on the elevator stick forces in accelerated f11ght. Another advantage of the springy tab is that it might be used to provide almost any desired variation of elevator stick force with speed by adjusting the tab hinge-moment characteristics and the variation of spring moment with tab deflection. Unlike the bungee and the bobweight, the springy tab would provide stick-free static stability without requiring a pull force to hold the stick back while taxying. A device similar to the springy tab may be used on the rudder or ailerons to eliminate undesirable trim-force variations with speed
CARMIL2 is a novel molecular connection between vimentin and actin essential for cell migration and invadopodia formation
Within‑marsh and Landscape Features Structure Ribbed Mussel Distribution in Georgia, USA, Marshes
Ribbed mussels, Geukensia demissa, are marsh fauna that are used in coastal management and restoration due to the ecosystem services they provide. Ribbed mussel restoration efforts may be improved with a greater understanding of the environmental drivers of ribbed mussel distribution at multiple spatial scales to predict areas where restoration could be successful. This study sought to estimate the effects of within-marsh (4 m) and landscape (500 m) factors on ribbed mussel distribution. Ribbed mussel densities were surveyed at 11 sites along the coast of Georgia, USA, and overlaid with spatial data for within-marsh factors (elevation, distance to marsh features, slope) as well as landscape factors (percent cover by subtidal creek, forest, and development within a 500-m radius). The distribution model was then validated using three previously unsurveyed marshes and explained 55% of the variance in ribbed mussel abundance. Ribbed mussel abundances and occupancy were most sensitive to changes in within-marsh factors (elevation and distance to subtidal creeks, bodies of water inundated during the full tidal cycle) but were also sensitive to landscape features (percent landcover of forests and development). The highest ribbed mussel densities were found in mid-elevation areas (~ 0.7 m NAVD88), far from subtidal creeks, and in marshes surrounded with forest and development. These results contrast with distributions in the northeastern USA, where ribbed mussels are distributed along subtidal creek banks. This work suggests that restoration may be most effective when focused on appropriate elevations and at locations away from the marsh-creek ecotone
Preparation and Characterization of Photoactive Antimicrobial Graphitic Carbon Nitride (g-C\u3csub\u3e3\u3c/sub\u3eN\u3csub\u3e4\u3c/sub\u3e) Films
Photoactive films derived from nanostructured samples of the metal-free, intermediate band gap semiconductor graphitic carbon nitride (ns-g-C3N4) have been synthesized and characterized for their particle properties and antimicrobial activity. Physical characterization reveals that these materials are composed of discrete nanoparticles whose dimensions range from 200 nm to 700 nm. Investigation of the photochemical reactivity of ns-g-C3N4 using coumarin-3- carboxylic acid (3-CCA) indicates that this material produces reactive oxygen species (ROS) under visible radiation. When irradiated with 0.31J visible light, ns-g-C3N4-based materials reduced the viability of both gram-negative Escherichia coli O157:H7 and gram-positive Staphylococcus aureus by approximately 50%. Nearly complete inactivation of both strains of microorganisms was achieved upon administration of a 0.62J dose of visible radiation. Importantly, no biocidal activity was observed for non-irradiated samples, indicating that the g-C3N4-derived films are not inherently toxic in the absence of visible light. The results of this study suggest that materials and, by extention, films and coatings derived from g-C3N4 may present a novel route for controlling pathogenic microorganisms on surfaces in the environment, and could be useful in reducing incidents of hospital-acquired infections
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