q-deformed dynamics and Josephson junction

We define a generalized rate equation for an observable in quantum mechanics, that involves a parameter q and whose limit $q\to 1$ gives the standard Heisenberg equation. The generalized rate equation is used to study dynamics of current biased Josephson junction. It is observed that this toy model incorporates diffraction like effects in the critical current. Physical interpretation for q is provided which is also shown to be q-deformation parameter.Comment: LaTeX 9 pages, submitted Mod. Phys. Lett. B, e-mail: [email protected]

Evaluation of novel glass-ionomer cements for hard tissue repair using in vitro and in vivo methods

Ionomeric cements (ICs) have a successful history as restorative materials in dentistry where they are called glass-ionomer cements (GICs). More recently they have potential for use as bone substitutes and cements in orthopaedic, otolaryngology and maxillofacial surgery. The influence of glass composition on IC properties such as biocompatibility has not been adequately studied. The broad aim of this research was to characterise a series of ICs of defined composition and evaluate their biocompatibility in vitro and in vivo. The hypothesis was that ICs could be optimised through their glass composition for clinical use as bone substitutes or cements. ICs are formed by the neutralisation reaction of an inorganic basic glass and organic polyelectrolyte acid. In vitro studies involved the determination of ions eluted from set cement discs and evaluation of the toxicology and biocompatibility of the ICs using cell culture techniques. In vivo studies involved the implantation of set and wet ICs into the midshaft of the rat femur. The osteoconduction and osseointegration of specified ICs were determined by histomorphometric analysis. Additionally, the role of noncollagenous extracellular matrix bone proteins were studied as they play an important role in the interactions of the healing of hard tissues with implants. The response of bone was dependent upon IC formulation with increase in fluoride and phosphate stimulating bone cell response. Bone response was negatively correlated with aluminium. It was concluded that the IC from the apatite stoichiometric series (designated LG26) had the most promising formulation for biomedical applications. This study confirmed that ICs have some potential clinical use as a bone substitute and cement. However, in vitro studies suggested that aluminium ions released from set ICs were responsible for some cytotoxicity and further work might usefully be directed at reducing the release of this ion from the cement

(How) does productivity matter in the foundational economy?

Academics and policy makers have increasingly recognised the importance of mundane economic activities – variously termed foundational or everyday – by academics and policy makers. The foundational or everyday economy is now featuring in local industrial strategy and economic action plans, because the desirable high-tech sectors on the ‘frontier’ cannot diffuse prosperity within and between regions. This paper aims to distinguish between several different approaches to the foundational or everyday economy and argues that a constructive approach needs to break with the preoccupation about improving productivity. This argument is developed in three stages. First, we distinguish between a social approach and a more technical economic approach to delimiting this other mundane economy; the defining feature of the foundational in the social approach is contribution to wellbeing and in the technical economic approach it is low productivity. The second section presents and explores productivity evidence on output per worker hour across a range of foundational activities and by region. Drawing out the implications of observed diversity and heterogeneity, the third section develops an argument about how productivity has limited relevance as measure and target in foundational activitie

Performance Evaluation of Multiple Differential Detection for Third Generation Mobile Communication System

Third generation mobile communication system is widely used nowadays. One of its parameter standard, which is QPSK modulation has been adopted by International Telecommunication Union (ITU) to be used in IMT-2000. However, due to amplitude variations introduced in QPSK, a rather robust and reliable data modulation technique, namely the p/4-shift Differential QPSK is proposed. For detection purposes, two types of detectors are evaluated for their performance in AWGN and Rayleigh fading channels.A differential detection technique called multiple differential detection technique which uses maximumlikelihood sequence estimation (MLSE) of the transmitted phases is compared with conventional differential detection which uses symbol-by-symbol detection. By using some of the IMT-2000 standard parameters, the simulation results show that multiple differential detection scheme performs much better than conventional differential detection scheme

National Vascular Registry: 2015 Annual Report.

The National Vascular Registry is commissioned by the Healthcare Quality Improvement Partnership (HQIP) to measure the quality and outcomes of care for patients who undergo major vascular surgery in NHS hospitals in England and Wales. It aims to provide comparative information on the performance of NHS vascular units and thereby support local quality improvement as well as inform patients about major vascular interventions delivered in the NHS. As such, all NHS hospitals in England, Wales, Scotland and Northern Ireland are encouraged to participate in the Registry. The measures used to describe the patterns and outcomes of care are drawn from various national guidelines including: the “Provision of Services for Patients with Vascular Disease” document and the Quality Improvement Frameworks published by the Vascular Society, and the National Institute for Health and Care Excellence (NICE) guidelines on stroke and peripheral arterial disease. This report provides a description of the care provided by NHS vascular units, and contains information on the process and outcomes of care for: (i) patients undergoing abdominal aortic aneurysm (AAA) repair, (ii) patients undergoing carotid endarterectomy, (iii) patients undergoing a revascularisation procedure (angioplasty/stent or bypass) or major amputation for lower-limb peripheral arterial disease (PAD). In addition, the report presents the findings of an organisational audit conducted in August 2015

Ruthenium volatilisation from reprocessed spent nuclear fuel - Studying the baseline thermodynamics of Ru(III)

Ruthenium is a fission product possessed of two relatively long lived isotopes, Ru and Ru, both of which form part of the Highly Active (HA) waste raffinate during spent nuclear fuel reprocessing. During reprocessing ruthenium, which may be in the form of the RuNO+ complex, encounters temperatures conducive to volatilization. Due rutheium's high specific radioactivity it is important to understand the mechanism by which volatilisation occurs. Here we use combined CV, RDE and electrochemical microgravimetry experiments in a study of the the RuCl3 system for the first time. We do this in the interest of establishing NO-free Ru(III) baseline behaviour so as to support future studies on NO complexed ruthenium. Using wide aqueous solvent window carbon electrodes we have observed discrete oxidations to a solution phase Ru(III)-Ru(IV)-Ru(III) trimer, to solid RuO2 and volatile RuO4. We have also observed and assigned discrete reductions of solid RuO2 back to Ru(III) and Ru(III) reduction to ruthenium metal

National Vascular Registry: 2014 Progress Report.

The National Vascular Registry is commissioned by the Healthcare Quality Improvement Partnership (HQIP) to measure the quality and outcomes of care for patients who undergo major vascular surgery in NHS hospitals in England and Wales. It aims to provide comparative information on the performance of NHS hospitals and thereby support local quality improvement as well as inform patients about the care delivered in the NHS. As such, all NHS hospitals in England, Wales, Scotland and Northern Ireland are encouraged to participate in the Registry. The measures used to describe the patterns and outcomes of care are drawn from various national guidelines including: the “2014 The Provision of Services for Patients with Vascular Disease” and the Quality Improvement Frameworks published by the Vascular Society, and the National Institute for Health and Care Excellence (NICE) guidelines on stroke and peripheral arterial disease. In 2014, the Registry published NHS trust and surgeon-level information for elective infrarenal Abdominal Aortic Aneurysm (AAA) repair and carotid endarterectomy on the Registry website. From 28 October, information on both procedures has been available on the www.vsqip.org.uk website for all UK NHS trusts that currently perform them. For English NHS trusts, the same information was published for individual consultants, as part of NHS England’s “Everyone Counts: Planning for Patients 2013/4” initiative. Consultant-level information was also published for NHS hospitals in Wales, Scotland and Northern Ireland for consenting surgeons. This progress report aims to complement that information by (1) providing an overview of care delivered by the NHS at a national level, and (2) describing various developments within the National Vascular Registry. The Registry will publish its next annual report on major vascular surgery in November 2015

5 year follow up of a hydroxyapatite coated short stem femoral component for hip arthroplasty: a prospective multicentre study

Short stem, uncemented femoral implants for hip arthroplasty are bone conserving achieving stability through initial metaphyseal press-fit and biological fixation. This study aimed to evaluate the survivorship, mid-term function and health related quality of life outcomes in patients who have undergone total hip arthroplasty (THA) with a fully hydroxyapatite coated straight short stem femoral component with up to 5 years follow-up. 668 patients were recruited to a multicentre study investigating the performance of the cementless Furlong Evolution® stem for THA. 137 patients withdrew at various time points. The mean follow-up was 49 months. Clinical (Harris Hip Score (HHS), radiographic and patient-reported outcome measures—Oxford Hip Score (OHS) and EuroQol 5D (EQ-5D), were recorded pre-operatively and at 6 weeks, 6 months, 1 year, 3 year and 5 year follow ups. At 5-year follow-up, 12 patients underwent revision surgery, representing a cumulative revision rate of 1.8%. Median OHS, HHS and EQ5D scores improved significantly: OHS improved from a pre-operative median of 21 (IQR 14–26) to 47 (IQR 44–48) (p < 0.001). HHS improved from 52 (IQR 40–63) to 98 (IQR 92–100) (p < 0.001) and EQ5D improved from 70 (IQR 50–80) to 85 (IQR 75–95) (p < 0.001). This fully HA-coated straight short femoral stem implant demonstrated acceptable mid-term survivorship and delivered substantial improvements in function and quality of life after THA

Disposition kinetics and dosage regimen of ceftriaxone in crossbred calves (Short Communication)

Disposition kinetics and urinary excretion of ceftriaxone were investigated in healthy crossbred calves after its single intravenous administration (10 mg kg–1). Based on kinetic parameters, an appropriate dosage regimen of ceftriaxone in calves was calculated. The peak plasma level of ceftriaxone at 1 min was 84.0 ± 1.55 μg ml–1 which declined to 0.43 ± 0.05 μg ml–1 at 8 h. The value of elimination half-life (t1/2α), volume of distribution Vd (area) and total body clearance (ClB) were 4.39 ± 0.63 h, 1.91 ± 0.19 L kg–1 and 0.31 ± 0.01 L kg–1 h–1, respectively. Approximately 41 per cent of total administered drug was recovered in the urine within 24 h of its administration. The plasma protein binding of ceftriaxone was found to be concentration dependent with an overall mean of 38.55 per cent. The binding capacity of ceftriaxone to plasma proteins and the dissociation rate constant of protein-drug complex were 20.1 × 10–8 ± 18.4 × 10–8 mole g–1 and 1.07 × 10–6 ± 0.52 × 10–6 mole, respectively. An appropriate intravenous dosage regimen of ceftriaxone in cattle would be 12 mg kg–1 repeated at 24 h