119 research outputs found

    Drone-Based Identification of Erosive Processes in Open-Pit Mining Restored Areas

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    Altres ajuts: European Union LIFE20 PRE/IT/000007Unmanned Aerial Systems, or drones, are very helpful tools for managing open-pit mining operations and developing ecological restoration activities. This article presents a method for identifying water erosion processes in active quarries by means of drone imagery remote sensing, in the absence of pre-existing imagery or mapping for comparison. A Digital Elevation Model (DEM) with a spatial resolution (SR) >10 cm and an orthophoto with an SR >2.5 cm were generated from images captured with a drone and their subsequent photogrammetric processing. By using Geographical Information Systems tools to process the DEM, a detailed drainage network was obtained, the areas of detected water erosion were separated, and the watersheds in the gullies identified. Subsequently, an estimated DEM before the erosive processes was reconstructed by interpolating the gully ridges; this DEM serves as a reference for the relief before the erosion. To calculate the volume of eroded material, the DEM of Differences was calculated, which estimates the volume difference between the previously estimated DEM and the current DEM. Additionally, we calculated the material necessary for the geomorphological adaptation of the quarry and the slope map, which are two valuable factors closely related to the monitoring of erosive processes. The results obtained allowed us to identify the erosion factors quickly and accurately in this type of mining. In the case of water-filled quarries, it would be important to characterize the subsurface relief. Essentially, the presented method can be applied with affordable and non-invasive materials to create digital grid maps at 10 cm resolution, obtaining data ready for 3D metrics, being a very practical landscape modelling tool for characterizing the restoration evolution of open-pit mining spaces

    UAS remote sensing products for supporting extraction management and restoration monitoring in open-pit mines

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    Accurate mapping of open-pit mine areas is a prerequisite for the efficient resource management of extractive companies, but also detailed mapping is a requirement for public administrations, especially regarding the monitoring of restored areas. In previous works, our team has contributed to a better knowledge of the use of Unmanned Aerial Systems (UAS) technologies for soil/vegetation restoration monitoring purposes, and in this work, we present a novel protocol to support combined interests of both private companies and governmental agencies. We introduce a case study in which we show the capability of multispectral sensors onboard of a low-weight multicopter to describe land cover typologies in restored areas (such as grass, scrubs, trees, topsoil and mine spoils) by applying remote sensing and GIS techniques. Moreover, we assess the capability of digital terrain models (Digital Elevation Model, Digital Surface Model, Digital Slope Model) derived from photogrammetric techniques, to provide useful and fast topographic information for the proper management of open-pit mine exploitation and restoration. By applying these techniques, we present a cost-effective workflow adequate to monitor land cover dynamics in restored areas, but also volumetric changes in stockpiles, waste dumps and extraction faces. This combined approach, supporting both environmental and industrial needs, aims to enhance the collaboration between sectors, establishing synergies, reducing costs by sharing knowledge, and adding transparency to their relation

    Engineering new mycobacterial vaccine design for HIV-TB pediatric vaccine vectored by lysine auxotroph of BCG

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    In this study, we have engineered a new mycobacterial vaccine design by using an antibiotic-free plasmid selection system. We assembled a novel Escherichia coli (E. coli)-mycobacterial shuttle plasmid p2auxo.HIVA, expressing the HIV-1 clade A immunogen HIVA. This shuttle vector employs an antibiotic resistance-free mechanism for plasmid selection and maintenance based on glycine complementation in E. coli and lysine complementation in mycobacteria. This plasmid was first transformed into glycine auxotroph of E. coli strain and subsequently transformed into lysine auxotroph of Mycobacterium bovis BCG strain to generate vaccine BCG.HIVA 2auxo. We demonstrated that the episomal plasmid p2auxo.HIVA was stable in vivo over a 7-week period and genetically and phenotypically characterized the BCG.HIVA 2auxo vaccine strain. The BCG.HIVA 2auxo vaccine in combination with modified vaccinia virus Ankara (MVA). HIVA was safe and induced HIV-1 and Mycobacterium tuberculosis -specific interferon-γ-producing T-cell responses in adult BALB/c mice. Polyfunctional HIV-1-specific CD8+ T cells, which produce interferon-γ and tumor necrosis factor-α and express the degranulation marker CD107a, were induced. Thus, we engineered a novel, safer, good laboratory practice-compatible BCG-vectored vaccine using prototype immunogen HIVA. This antibiotic-free plasmid selection system based on "double" auxotrophic complementation might be a new mycobacterial vaccine platform to develop not only recombinant BCG-based vaccines expressing second generation of HIV-1 immunogens but also other major pediatric pathogens to prime protective response soon after birth

    Tuberculosis recurrence after completion treatment in a European city: reinfection or relapse?

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    Background Tuberculosis (TB) recurrence can be due to reinfection or relapse. The contribution of each to TB incidence and the factors associated with recurrence are not well known. Effectiveness of TB control programs is assessed in part by recurrence rates. The aim of this study was to establish the recurrence rate of TB in Barcelona, the associated risk factors and the role of reinfection. Methods A population-based retrospective longitudinal study was performed in Barcelona, Spain. TB patients with positive culture results who completed treatment between Jan 1st, 2003 and Dec 31st, 2006 were followed-up until December 31st, 2009 by the TB Control Program. The incidence rate of recurrence was calculated per person-year of follow-up (py). Kaplan-Meier and Cox regression methods were used for the survival analysis by calculating the hazard ratio (HR) with 95% confidence intervals (CI). Results Of the 1,823 TB cases identified, 971 fulfilled the inclusion criteria and 13 (1.3%) had recurrent TB. The recurrence rate was 341 cases per 100,000 py, 13 times higher than the TB incidence of the general population. Likelihood of TB recurrence at the 1st, 3rd and 5th year of follow-up was 0.1%, 1.4% and 1.6%, respectively. Factors associated with recurrence were HIV infection (HR: 4.7, CI: 1.4-15.7), living in the inner city district (HR: 3.9, CI: 1.3-11.8) and history of TB treatment (HR: 5.2, CI: 1.7-16.2). Genotyping results of recurrent cases were available for 6 patients (3 reinfections and 3 relapses). Conclusion The rate of TB recurrence in Barcelona is low and most episodes occur within the first three years. Patients at higher risk of recurrence are co-infected with HIV, living in neighborhoods with high TB incidence or with a history of TB treatment. When available, genotyping results help determine whether the recurrence is due to reinfection or relapse

    Evaluation and assessment of professional skills in the Final Year Project

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    In this paper, we present a methodology for Final Year Project (FYP) monitoring and assessment that considers the inclusion of the professional skills required in the particular engineering degree. This proper monitoring and clear evaluation framework provides the student with valuable support for the project implementation as well as for improving the quality of the projects, thereby reducing the academic drop-out rate. The proposed methodology has been implemented at the Barcelona School of Informatics at the Universitat Politècnica de Catalunya - BarcelonaTech. The FYP is structured around three milestones: project definition, project monitoring and project completion. Skills are assigned to each milestone according to the tasks required in that phase, and a list of indicators is defined for each phase. The evaluation criteria for each indicator at each phase are specified in a rubric, and are made public both to students and teachers. Thus, the FYP includes an exhaustive evaluation method distributed throughout the whole project implementation, thereby facilitating project organization for the student as well as providing a clear and homogeneous assessment framework. The methodology for the FYP organization, assessment and evaluation was launched and piloted over two semesters. We believe the experience to be general in the sense that it has been conducted as part of an ICT engineering degree, but may easily be extended to any other engineering degree.Postprint (author’s final draft

    Re-design of a component of a lower-limb robotic exoskeleton for integrating sensing capacity and enhancing multi-material direct additive manufacturing

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    The quest for the materialisation of advanced products is expanding the need for intelligent components and devices. One of the fields of application for such products is the medical technology industry, in which many value-added products could benefit from extending its embedded functionalities. To this regard, the obtention of such products via Additive Manufacturing Technologies would be very beneficial, providing that the design requirements could be met in a seamless and direct manner. In this context, the present article develops and analyses three design iterations of a component of a lower-limb robotic exoskeleton for integrating sensing capacity on it via multi-material direct additive manufacturing. In subsequent steps, the component geometry is optimised for additive direct manufacturing, and different functionalities are incorporated (padding for comfort and circuitry for sensing). For each iteration, the design is validated by means of finite element analysis and the main manufacturing parameters are assessed to compare the different times and costs yield. The third redesign incorporates three different materials (ABS, TPU and PE+Cu), but still it is possible to be 3D printed with a two extruder-head FDM 3D printer. The design and manufacturing results obtained could be implemented in further biomedical products or other parts requiring advanced functionalities.Peer ReviewedObjectius de Desenvolupament Sostenible::9 - Indústria, Innovació i InfraestructuraObjectius de Desenvolupament Sostenible::3 - Salut i BenestarPostprint (published version

    Predictors of Death among Patients Who Completed Tuberculosis Treatment: A Population-Based Cohort Study

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    Background: Mortality among patients who complete tuberculosis (TB) treatment is still high among vulnerable populations. The objective of the study was to identify the probability of death and its predictive factors in a cohort of successfully treated TB patients. Methods: A population-based retrospective longitudinal study was performed in Barcelona, Spain. All patients who successfully completed TB treatment with culture-confirmation and available drug susceptibility testing between 1995-1997 were retrospectively followed-up until December 31, 2005 by the Barcelona TB Control Program. Socio-demographic, clinical, microbiological and treatment variables were examined. Mortality, TB Program and AIDS registries were reviewed. Kaplan-Meier and a Cox regression methods with time-dependent covariates were used for the survival analysis, calculating the hazard ratio (HR) with 95% confidence intervals (CI). Results: Among the 762 included patients, the median age was 36 years, 520 (68.2%) were male, 178 (23.4%) HIV-infected, and 208 (27.3%) were alcohol abusers. Of the 134 (17.6%) injecting drug users (IDU), 123 (91.8%) were HIV-infected. A total of 30 (3.9%) recurrences and 173 deaths (22.7%) occurred (mortality rate: 3.4/100 person-years of follow-up). The predictors of death were: age between 41-60 years old (HR: 3.5; CI:2.1-5.7), age greater than 60 years (HR: 14.6; CI:8.9-24), alcohol abuse (HR: 1.7; CI:1.2-2.4) and HIV-infected IDU (HR: 7.9; CI:4.7-13.3). Conclusions: The mortality rate among TB patients who completed treatment is associated with vulnerable populations such as the elderly, alcohol abusers, and HIV-infected IDU. We therefore need to fight against poverty, and promote and develop interventions and social policies directed towards these populations to improve their survival

    Black Rings in Taub-NUT and D0-D6 interactions

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    We analyze the dynamics of neutral black rings in Taub-NUT spaces and their relation to systems of D0 and D6 branes in the supergravity approximation. We employ several recent techniques, both perturbative and exact, to construct solutions in which thermal excitations of the D0-branes can be turned on or off, and the D6-brane can have BB-fluxes turned on or off in its worldvolume. By explicit calculation of the interaction energy between the D0 and D6 branes, we can study equilibrium configurations and their stability. We find that although D0 and D6 branes (in the absence of BB fields, and at zero temperature) repeal each other at non-zero separation, as they get together they go over continuosly to an unstable bound state of an extremal singular Kaluza-Klein black hole. We also find that, for BB-fields larger than a critical value, or sufficiently large thermal excitation, the D0 and D6 branes form stable bound states. The bound states with thermally excited D0 branes are black rings in Taub-NUT, and we provide an analysis of their phase diagram.Comment: 50 pages, 8 figures; v3: minor changes and references added; v4: improved figs. 7 and 8, matches with published versio
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