FADIGA E NÍVEL DE CAPACIDADE FUNCIONAL EM PACIENTES ONCOLÓGICOS

Introdução: O câncer tem um grande impacto na qualidade de vida dos indivíduos. Entre outras queixas comumente descritasestão a fadiga, perda de força muscular e dor. Objetivo: Avaliar o sintoma de fadiga e nível de capacidade funcional em pacientesoncológicos. Métodos: Trata-se de uma pesquisa transversal, prospectiva, de natureza quantitativa, realizada em um HospitalPúblico do Piauí. Foram avaliados indivíduos em sua primeira sessão de quimioterapia sendo investigados dados demográficos,clínicos, capacidade funcional por meio do Teste sentar-levantar da cadeira em 30s e o nível de fadiga através do questionárioFunctional Assessment of Chronic Illness Therapy – FACIT subescala (FACIT – Fadiga). Resultados: Foram avaliados 43 pacientes,55,8% do sexo feminino idade 59,9±14,2 anos. Com relação à capacidade funcional observou-se uma média de 11,7repetições para ambos os sexos, sendo abaixo do esperado. Quanto ao nível de fadiga dos indivíduos obteve-se uma média de40,8±8,2 (mínimo=21; máximo=52) em uma escala de 0 a 52. Conclusão: Pacientes oncológicos apresentaram sintomas defadigas e redução de capacidade funcional. A intensidade de fadiga foi maior no estadiamento mais avançado e presença demetástases. O sexo feminino apresentou associação entre maior fadiga e menor capacidade funcional.Palavras-chave: Aptidão Física. Câncer. Fadiga

Análise da ação do gel da Bryophyllum calycinum Salisb (folha santa) associado ao ultrassom na cicatrização de feridas cutâneas

Introduction: Healing is a cascade of cellular events that interact to occur replen-ish the tissue. Objective: To analyze the action of the Bryophyllum calycinum Salisb gel associated with the pulsed ultrasound in wound healing. Methods: Twenty rats were wounded and divided into four groups. After this, they were treated and observed daily. Group 1 did not receive any treatment; Group 2 was treated with ultrasound (10% pulsed mode, frequency of 1 MHz intensity of 0.5 W / cm2, direct coupling method with an oscillatory motion was 1 cm2 for two minutes) + Gel B. calycinum Salisb 2%; Group 3, with B. calycinum Salisb gel 2%; and Group 4, with ultrasound. Results: Group 2 had a greater reduction in wound areas, a decrease of type III collagen and an increase of the type I when compared to the control group. Conclusions: The gel of the holy sheet associated with ultrasound is able to accelerate the wound healing process

Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

Objective To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods. We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results. There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95% confidence interval [CI] −11.7 to −11.3, p \u3c 0.0001) decline. There were 13,334 IVT therapies in the 4 months preceding compared to 11,570 procedures during the pandemic, representing a 13.2% (95% CI −13.8 to −12.7, p \u3c 0.0001) drop. Interfacility IVT transfers decreased from 1,337 to 1,178, or an 11.9% decrease (95% CI −13.7 to −10.3, p = 0.001). Recovery of stroke hospitalization volume (9.5%, 95% CI 9.2–9.8, p \u3c 0.0001) was noted over the 2 later (May, June) vs the 2 earlier (March, April) pandemic months. There was a 1.48% stroke rate across 119,967 COVID-19 hospitalizations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was noted in 3.3% (1,722/52,026) of all stroke admissions. Conclusions. The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months