813 research outputs found

    Guaranteed Quality of Service in Multimedia System

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    AbstractGuaranteed quality of service (QoS) and aggregate data throughput is needed for a variety of applications ranging from real-time data collection to multimedia applications. This paper presents a novel design and implementation technique called QoS and aggregate data throughput scheduling model (QTT) which solves the availability bandwidth and aggregate throughput problems in resource reservation system. The QTT is composed of batch generation module (BGM) and PEM. The BGM selects requests from reservation queue and places them in a batch. The PEM schedules requests in each batch to achieve the maximal aggregate throughput while providing a given level of QoS guarantees. The experimental results indicate that our scheduling model achieves remarkable aggregate throughput under a given level of QoS guarantees

    Solubility of MgO in chloride melts containing NdCl3 or LaCl3

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    Due to extremely low solubility in conventional magnesium electrolyte, MgO tends to attach to cathode and causes cathodic passivation, which will dramatically lower current efficiency of magnesium electrolysis. In this paper, NdCl3 or LaCl3 was added to conventional magnesium electrolyte to increase MgO solubility. We investigated the effects of NdCl3 or LaCl3 content, the form of MgO, and temperature on the dissolution rate of MgO and on MgO solubility. MgO solubility increased with increasing MgCl2 content of CaF2 content in MgCl2 -KCL-NaCL-CaCl2-CaF2 melt, the maximum being only 0.145% by weight in the above melt with 30% MgCl2 by weight. Both MgO solubility and dissolution rate increased with increasing NdCl3 concentration in MgCl2-NaCl-KCl-NdCl3 (15% by weight) melts can reach about 3.0 wt % at 780 C. Raising temperature from 700 to 800 C can slightly increase the MgO solubility and dissolution rate. Addition of LaCl3 to the MgCl2-NaCl-KCl-CaCl2-LaCl3 melt also improved MgO solubility, but it took more time (about 60 minutes) to achieve equilibrium between MgO and LaCl3 in the melt. Formation of the stable NdOCl compound examined by XRD analysis indicated that MgO can react with NdCl3 in chloride melts

    Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma

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    BACKGROUND: Teniposide (VM-26) has been widely used in the treatment of small cell lung cancer, malignant lymphoma, breast cancer, etc. However, there are few reports on VM-26 against oral cancers. The present study was designed to identify the effect of VM-26 against oral squamous cell carcinoma in vitro, and to provide evidence for the feasibility and effectiveness of VM-26 for application to the patients with oral cancer. METHODS: Human tongue squamous cell carcinoma cell line, Tca8113, was used. Cells were incubated with different concentrations of VM-26 for a variety of time span. Cisplatin (CDDP) was employed as a control reagent. MTT assay was used to assess the inhibitory rate of Tca8113 growth. Flow cytometer (FCM), transmission electronic microscope (TEM) and fluorescence staining were employed for determining the cell apoptotic rate. Cell cycle distribution of Tca8113 incubated with VM-26 was examined by flow cytometer assay. Statistic software (SAS 6.12, USA) was used for one-way ANOVA. RESULTS: The IC50 of VM-26 against Tca8113 cells was 0.35 mg/l and that of CDDP was 1.1 mg/l. The morphological changes of Tca8113 cells were observed with fluorescence microscope and TEM. Apoptotic morphological feature could be found in the nucleus. Apoptotic rate of Tca8113 cells incubated with 5.0 mg/l of VM-26 for 72 hours was 81.67% and cells waere arrested at S phase. However, when exposed to 0.15 mg/l of VM-26 for 72 hours, G2/M phase increased from 12.75% to 98.71%, while the apoptotic rate was 17.38%, which was lower than that exposed to 5.0 mg/l of VM-26. CONCLUSION: VM-26 could significantly induce apoptosis of oral squamous cell carcinoma and inhibit cell growth. There may be another pathway to induce apoptosis of oral squamous cell carcinoma cells except for G2/M phase arrest

    Construction and Characterization of a Chimeric Virus (BIV/HIV-1) Carrying the Bovine Immunodeficiency Virus \u3ci\u3egag\u3c/i\u3e-\u3ci\u3epol\u3c/i\u3e Gene: Research Letters

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    HIV-1HXB2 5′LTR region, most of BIVR29 gag-pol segment and HIV-1HXB2 pol IN-3′LTR region were respectively amplified. A chimeric clone, designated as pHBIV3753, was constructed by cloning three fragments sequentially into pUC18. MT4 cells were transfected with pHBIV3753. The replication and expressions of the chimeric virus (HBIV3753) were monitored by RT activity and IFA. The results firstly demonstrated that it is possible to generate a new type of the BIV/HIV-1 chimeric virus containing BIV gag-pol gene

    Simultaneous assimilation of Fengyun-4A and Himawari-8 aerosol optical depth retrieval to improve air quality simulations during one storm event over East Asia

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    Aerosols are the main components of air pollutants, which are closely related to haze, dust storm and air pollution. In this study, an aerosol data assimilation system was developed using Gridpoint Statistical Interpolation (GSI) system to assimilate the Aerosol Optical Depth (AOD) observations from FY4 and Himawari-8 for the first time and applied in the heavy dust case over east Asia in March 2018. Three parallel experiments assimilated AOD from FY4, Himawari-8 and both the FY4 and Himawari-8 respectively and a control experiment which did not employ DA were performed. The hourly aerosol analyses and forecasts are compared with the assimilated FY-4 AOD, Himawari-8 AOD and independent AOD from Aerosol Robotic Network (AERONET). The results showed that all forms of DA experiments improved a low Bias and the RMSE reduced about 20%. The aerosol data assimilation with observations from both the FY-4 and Himawari-8 satellites substantially improved aerosol analyses and subsequent forecasts with more abundant aerosol observation information, especially over the northwest of China. This study indicates that the new generation geostationary meteorological satellites have potential to dramatically contribute to air quality forecasting
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