3,778 research outputs found
Green 5G Heterogeneous Networks through Dynamic Small-Cell Operation
Traditional macro-cell networks are experiencing an upsurge of data traffic,
and small-cells are deployed to help offload the traffic from macro-cells.
Given the massive deployment of small-cells in a macro-cell, the aggregate
power consumption of small-cells (though being low individually) can be larger
than that of the macro-cell. Compared to the macro-cell base station (MBS)
whose power consumption increases significantly with its traffic load, the
power consumption of a small-cell base station (SBS) is relatively flat and
independent of its load. To reduce the total power consumption of the
heterogeneous networks (HetNets), we dynamically change the operating states
(on and off) of the SBSs, while keeping the MBS on to avoid any service failure
outside active small-cells. First, we consider that the wireless users are
uniformly distributed in the network, and propose an optimal location-based
operation scheme by gradually turning off the SBSs closer to the MBS. We then
extend the operation problem to a more general case where users are
non-uniformly distributed in the network. Although this problem is NP-hard, we
propose a joint location and user density based operation scheme to achieve
near-optimum (with less than 1\% performance loss in our simulations) in
polynomial time.Comment: The longer version of a paper to appear in IEEE Journal on Selected
Areas in Communications, green communications and networking serie
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A 25-hydroxycholecalciferol–fortified dairy drink is more effective at raising a marker of postprandial vitamin D status than cholecalciferol in men with suboptimal vitamin D status
Background: One strategy for improving population vitamin D status is consumption of fortified foods. However, the
effects of dairy products fortified with different vitamin D isoforms on postprandial vitamin D status and metabolic
outcomes have not been addressed.
Objective: We investigated whether consumption of dairy drinks fortified with either 25-hydroxycholecalciferol [25(OH)D3] or
cholecalciferol (vitamin D3) had differential effects on 24-h circulating plasma 25(OH)D3 concentration (a marker of vitamin
D status) and cardiometabolic risk markers.
Methods: A randomized, controlled, 3-way crossover, double-blind, postprandial study was conducted in 17 men with
suboptimal vitamin D status [mean 6 SEM age: 49 6 3 y; body mass index (in kg/m2): 26.4 6 0.6; and plasma 25(OH)D3
concentration: 31.7 6 3.4 nmol/L]. They were randomly assigned to consume 3 different test meals (4.54 MJ, 51 g fat, 125 g
carbohydrate, and 23 g protein),which contained either a nonfortified dairy drink (control), 20 mg 25(OH)D3-fortified (+HyD3) dairy
drink, or 20 mg vitamin D3–fortified (+D3) dairy drink with toasted bread and jam on different occasions, separated by a 2-wk
washout. Plasma 25(OH)D3 concentrations and cardiometabolic risk markers, including vascular stiffness, serum lipids, and
inflammatory markers, were measured frequently within 8 h postprandially and 24 h after the dairy drink was consumed.
Results: Plasma 25(OH)D3 concentrations (the primary outcome) were significantly higher after the +HyD3 dairy drink was
consumed compared with +D3 and control (P = 0.019), which was reflected in the 1.5-fold and 1.8-fold greater incremental
area under the curve for the 0–8 h response, respectively. The change in plasma 25(OH)D3 concentrations from baseline to
24 h for the +HyD3 dairy drink was also 0.9-fold higher than the +D3 dairy drink and 4.4-fold higher than the control
(P < 0.0001), which were not significantly different from each other.
Conclusion: The dairy drink fortified with 25(OH)D3 was more effective at raising plasma 25(OH)D3 concentrations
postprandially than was the dairy drink fortified with vitamin D3 in men with suboptimal vitamin D status
Persistent spin current in mesoscopic ferrimagnetic spin ring
Using a semiclassical approach, we study the persistent magnetization current
of a mesoscopic ferrimagnetic ring in a nonuniform magnetic field. At zero
temperature, there exists persistent spin current because of the quantum
fluctuation of magnons, similar to the case of an antiferromagnetic spin ring.
At low temperature, the current shows activation behavior because of the
field-induced gap. At higher temperature, the magnitude of the spin current is
proportional to temperature T, similar to the reported result of a
ferromagnetic spin ring.Comment: 6 pages, 3 figures, one more reference adde
Selection and environmental adaptation along a path to speciation in the Tibetan frog Nanorana parkeri.
Tibetan frogs, Nanorana parkeri, are differentiated genetically but not morphologically along geographical and elevational gradients in a challenging environment, presenting a unique opportunity to investigate processes leading to speciation. Analyses of whole genomes of 63 frogs reveal population structuring and historical demography, characterized by highly restricted gene flow in a narrow geographic zone lying between matrilines West (W) and East (E). A population found only along a single tributary of the Yalu Zangbu River has the mitogenome only of E, whereas nuclear genes of W comprise 89-95% of the nuclear genome. Selection accounts for 579 broadly scattered, highly divergent regions (HDRs) of the genome, which involve 365 genes. These genes fall into 51 gene ontology (GO) functional classes, 14 of which are likely to be important in driving reproductive isolation. GO enrichment analyses of E reveal many overrepresented functional categories associated with adaptation to high elevations, including blood circulation, response to hypoxia, and UV radiation. Four genes, including DNAJC8 in the brain, TNNC1 and ADORA1 in the heart, and LAMB3 in the lung, differ in levels of expression between low- and high-elevation populations. High-altitude adaptation plays an important role in maintaining and driving continuing divergence and reproductive isolation. Use of total genomes enabled recognition of selection and adaptation in and between populations, as well as documentation of evolution along a stepped cline toward speciation
Stem cell protein Piwil1 endowed endometrial cancer cells with stem-like properties via inducing epithelial-mesenchymal transition
Exploring interfacial exchange coupling and sublattice effect in heavy metal/ferrimagnetic insulator heterostructures using Hall measurements, x-ray magnetic circular dichroism, and neutron reflectometry
We use temperature-dependent Hall measurements to identify contributions of
spin Hall, magnetic proximity, and sublattice effects to the anomalous Hall
signal in heavy metal/ferrimagnetic insulator heterostructures with
perpendicular magnetic anisotropy. This approach enables detection of both the
magnetic proximity effect onset temperature and the magnetization compensation
temperature and provides essential information regarding the interfacial
exchange coupling. Onset of a magnetic proximity effect yields a local extremum
in the temperature-dependent anomalous Hall signal, which occurs at higher
temperature as magnetic insulator thickness increases. This magnetic proximity
effect onset occurs at much higher temperature in Pt than W. The magnetization
compensation point is identified by a sharp anomalous Hall sign change and
divergent coercive field. We directly probe the magnetic proximity effect using
x-ray magnetic circular dichroism and polarized neutron reflectometry, which
reveal an antiferromagnetic coupling between W and the magnetic insulator.
Finally, we summarize the exchange-coupling configurations and the anomalous
Hall-effect sign of the magnetized heavy metal in various heavy metal/magnetic
insulator heterostructures
A genome draft of the legless anguid lizard, Ophisaurus gracilis
BACKGROUND: Transition from a lizard-like to a snake-like body form is one of the most important transformations in reptilian evolution. The increasing number of sequenced reptilian genomes is enabling a deeper understanding of vertebrate evolution, although the genetic basis of the loss of limbs in reptiles remains enigmatic. Here we report genome sequencing, assembly, and annotation for the Asian glass lizard Ophisaurus gracilis, a limbless lizard species with an elongated snake-like body form. Addition of this species to the genome repository will provide an excellent resource for studying the genetic basis of limb loss and trunk elongation. FINDINGS: O. gracilis genome sequencing using the Illumina HiSeq2000 platform resulted in 274.20 Gbp of raw data that was filtered and assembled to a final size of 1.78 Gbp, comprising 6,717 scaffolds with N50 = 1.27 Mbp. Based on the k-mer estimated genome size of 1.71 Gbp, the assembly appears to be nearly 100% complete. A total of 19,513 protein-coding genes were predicted, and 884.06 Mbp of repeat sequences (approximately half of the genome) were annotated. The draft genome of O. gracilis has similar characteristics to both lizard and snake genomes. CONCLUSIONS: We report the first genome of a lizard from the family Anguidae, O. gracilis. This supplements currently available genetic and genomic resources for amniote vertebrates, representing a major increase in comparative genome data available for squamate reptiles in particular
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