Bibliografía usada en la formación matemática del profesorado de infantil

Para realizar el estudio se escogió una muestra de 13 universidades españolas en las que se imparte la titulación y cuyas guías docentes son accesibles desde sus páginas webs. Se descargaron todas las guías docentes y se pasó la información a una base de datos ad hoc. Se realizó un proceso de estandarización de los nombres y de las referencias porque para cada asignatura utilizan formatos distintos incluso en la misma universidad. Se obtuvieron 493 referencias, que se presentan como bibliografía básica, específica, recomendada o complementaria. Posteriormente se hicieron conteos de frecuencias de cada autor, referencia y año para determinar la antigüedad de las mismas

Distinguished trajectories in time dependent vector fields

We introduce a new definition of distinguished trajectory that generalises the concepts of fixed point and periodic orbit to aperiodic dynamical systems. This new definition is valid for identifying distinguished trajectories with hyperbolic and non-hyperbolic types of stability. The definition is implemented numerically and the procedure consist in determining a path of limit coordinates. It has been successfully applied to known examples of distinguished trajectories. In the context of highly aperiodic realistic flows our definition characterises distinguished trajectories in finite time intervals, and states that outside these intervals trajectories are no longer distinguished.Comment: Chaos 19 (2009), 013111-1-013111-1

Identificando las relaciones dimensionales de la escala de actitudes hacia las matemáticas propuesta por Auzmendi en maestros en formación

Diversas investigaciones señalan que las actitudes hacia contenidos o asignaturas de Matemáticas atienden a uno de los factores más influyentes en la futura labor docente de los maestros en formación. Por ello, consideramos que es necesario y de interés comparar las diferentes dimensiones que posee la actitud hacia las matemáticas entre los alumnos de Educación Primaria, debido a que en el grado que están estudiando deben adquirir tanto conocimientos de Matemáticas como la capacidad para impartirlos en su futuro empeño laboral

The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection

Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from that of B lymphoblasts. We discuss the case of a 3-month infant with an active cytomegalovirus infection, with hepatitis and pancytopenia associated with 13% hematogones in the bone marrow

Big rip avoidance via black holes production

We consider a cosmological scenario in which the expansion of the Universe is dominated by phantom dark energy and black holes which condense out of the latter component. The mass of black holes decreases via Hawking evaporation and by accretion of phantom fluid but new black holes arise continuously whence the overall evolution can be rather complex. We study the corresponding dynamical system to unravel this evolution and single out scenarios where the big rip singularity does not occur.Comment: 16 pages, two figures. Key words. Cosmology, phantom energy, black holes. Sligthly extended version to be published in Gravitation and Cosmolog

Evolution of a Kerr-Newman black hole in a dark energy universe

This paper deals with the study of the accretion of dark energy with equation of state $p=w\rho$ onto Kerr-Newman black holes. We have obtained that when $w>-1$ the mass and specific angular momentum increase, and that whereas the specific angular momentum increases up to a given plateau, the mass grows up unboundedly. On the regime where the dominant energy condition is violated our model predicts a steady decreasing of mass and angular momentum of black holes as phantom energy is being accreted. Masses and and angular momenta of all black holes tend to zero when one approaches the big rip. The results that cosmic censorship is violated and that the black hole size increases beyond the universe size itself are discussed in terms of considering the used models as approximations to a more general descriptions where the metric is time-dependent.Comment: 11 figures added. Some explanations extended. E-mails updated. References updated. Conclusions unchanged. Accepted in Gravitation & Cosmolog

Imported malaria in pregnancy in Madrid

<p>Abstract</p> <p>Background</p> <p>Malaria in pregnancy is associated with maternal and foetal morbidity and mortality in endemic areas, but information on imported cases to non-endemic areas is scarce.</p> <p>The aim of this study was to describe the clinical and epidemiological characteristics of malaria in pregnancy in two general hospitals in Madrid, Spain.</p> <p>Methods</p> <p>Retrospective descriptive study of laboratory-confirmed malaria in pregnant women at the Fuenlabrada University Hospital and the Príncipe de Asturias University Hospital, in Madrid, over a six- and 11-year period, respectively. Relevant epidemiological, clinical and laboratory data was obtained from medical records.</p> <p>Results</p> <p>There were 19 pregnant women among 346 malaria cases (5.4%). The average age was 27 years. The gestational age (trimester) was: 53% 3^rd, 31% 1st, 16% 2^nd. All but one were multigravidae. Three were HIV positive. All were sub-Saharan immigrants: two were recently arrived immigrants and seventeen (89%) had visited friends and relatives. None had taken prophylaxis nor seeked pre-travel advice. Presentation: 16 symptomatic patients (fever in fourteen, asthenia in two), three asymptomatic. Median delay in diagnosis: 7.5 days. Laboratory tests: anaemia (cut off Hb level 11 g/dl) 78.9% (mild 31.6%, moderate 31.6%, severe 15.8%) thrombocytopaenia 73.7%, hypoglycaemia 10.5%. All cases were due to <it>Plasmodium falciparum</it>, one case of hyperparasitaemia. Quinine + clindamycin prescribed in 84%. Outcomes: no severe maternal complications or deaths, two abortions, fifteen term pregnancies, no low-birth-weight newborns, two patients were lost to follow-up.</p> <p>Conclusions</p> <p>Though cases of malaria in pregnancy are uncommon, a most at risk group is clearly defined: young sub-Saharan mothers visiting friends and relatives without pre-travel counselling and recently-arrived immigrants. The most common adverse maternal and foetal effects were anaemia and stillbirth. Given that presentation can be asymptomatic, malaria should always be considered in patients with unexplained anaemia arriving from endemic areas. These findings could help Maternal Health programme planners and implementers to target preventive interventions in the immigrant population and should create awareness among clinicians.</p

A Novel Circulating MicroRNA for the Detection of Acute Myocarditis.

The diagnosis of acute myocarditis typically requires either endomyocardial biopsy (which is invasive) or cardiovascular magnetic resonance imaging (which is not universally available). Additional approaches to diagnosis are desirable. We sought to identify a novel microRNA for the diagnosis of acute myocarditis. To identify a microRNA specific for myocarditis, we performed microRNA microarray analyses and quantitative polymerase-chain-reaction (qPCR) assays in sorted CD4+ T cells and type 17 helper T (Th17) cells after inducing experimental autoimmune myocarditis or myocardial infarction in mice. We also performed qPCR in samples from coxsackievirus-induced myocarditis in mice. We then identified the human homologue for this microRNA and compared its expression in plasma obtained from patients with acute myocarditis with the expression in various controls. We confirmed that Th17 cells, which are characterized by the production of interleukin-17, are a characteristic feature of myocardial injury in the acute phase of myocarditis. The microRNA mmu-miR-721 was synthesized by Th17 cells and was present in the plasma of mice with acute autoimmune or viral myocarditis but not in those with acute myocardial infarction. The human homologue, designated hsa-miR-Chr8:96, was identified in four independent cohorts of patients with myocarditis. The area under the receiver-operating-characteristic curve for this novel microRNA for distinguishing patients with acute myocarditis from those with myocardial infarction was 0.927 (95% confidence interval, 0.879 to 0.975). The microRNA retained its diagnostic value in models after adjustment for age, sex, ejection fraction, and serum troponin level. After identifying a novel microRNA in mice and humans with myocarditis, we found that the human homologue (hsa-miR-Chr8:96) could be used to distinguish patients with myocarditis from those with myocardial infarction. (Funded by the Spanish Ministry of Science and Innovation and others.).Supported by a grant (PI19/00545, to Dr. Martín) from the Ministry of Science and Innovation through the Carlos III Institute of Health–Fondo de Investigación Sanitaria; by a grant from the Biomedical Research Networking Center on Cardiovascular Diseases (to Drs. Martín, Sánchez-Madrid, and Ibáñez); by grants (S2017/BMD-3671-INFLAMUNE-CM, to Drs. Martín and Sánchez-Madrid; and S2017/BMD-3867-RENIM-CM, to Dr. Ibáñez) from Comunidad de Madrid; by a grant (20152330 31, to Drs. Martín, Sánchez-Madrid, and Alfonso) from Fundació La Marató de TV3; by grants (ERC-2011-AdG 294340-GENTRIS, to Dr. Sánchez-Madrid; and ERC-2018-CoG 819775-MATRIX, to Dr. Ibáñez) from the European Research Council; by grants (SAF2017-82886R, to Dr. Sánchez-Madrid; RETOS2019-107332RB-I00, to Dr. Ibáñez; and SAF2017-90604-REDT-NurCaMeIn and RTI2018-095928-BI00, to Dr. Ricote) from the Ministry of Science and Innovation; by Fondo Europeo de Desarrollo Regional (FEDER); and by a 2016 Leonardo Grant for Researchers and Cultural Creators from the BBVA Foundation to Dr. Martín. The National Center for Cardiovascular Research (CNIC) is supported by the Carlos III Institute of Health, the Ministry of Science and Innovation, the Pro CNIC Foundation, and by a Severo Ochoa Center of Excellence grant (SEV-2015-0505). Mr. Blanco-Domínguez is supported by a grant (FPU16/02780) from the Formación de Profesorado Universitario program of the Spanish Ministry of Education, Culture, and Sports. Ms. Linillos-Pradillo is supported by a fellowship (PEJD-2016/BMD-2789) from Fondo de Garantía de Empleo Juvenil de Comunidad de Madrid. Dr. Relaño is supported by a grant (BES-2015-072625) from Contratos Predoctorales Severo Ochoa para la Formación de Doctores of the Ministry of Economy and Competitiveness. Dr. Alonso-Herranz is supported by a fellowship from La Caixa–CNIC. Dr. Caforio is supported by Budget Integrato per la Ricerca dei Dipartimenti BIRD-2019 from Università di Padova. Dr. Das is supported by grants (UG3 TR002878 and R35 HL150807) from the National Institutes of Health and the American Heart Association through its Strategically Focused Research Networks.S