72 research outputs found

    A Short Note On Sums of Powers of Reciprocals of Polygonal Numbers

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    This paper presents the summation of powers of reciprocals of polygonal numbers. Several summation formulas of the reciprocals of generalized polygonal numbers are presented as examples of specific cases in this paper

    Navigating in Patient Space Using Camera Pose Estimation Relative to the External Anatomy

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    Ultrasound probe localization is essential for volumetric imaging with a 2D ultrasound probe, and for establishing a recorded anatomical context for ultrasound-guided surgery and for longitudinal studies. The existing techniques for probe localization, however, require external tracking devices, making them inconvenient for clinical use. In addition, the probe pose is typically measured with respect to a fixed coordinate system independent of the patient’s anatomy, making it difficult to correlate ultrasound studies across time. This dissertation concerns the development and evaluation of a novel self-contained ultrasound probe tracking system, which navigates the probe in patient space using camera pose estimation relative to the anatomical context. As the probe moves in patient space, a video camera on the probe is used to automatically identify natural skin features and subdermal cues, and match them with a pre-acquiring high-resolution 3D surface map that serves as an atlas of the anatomy. We have addressed the problem of distinguishing rotation from translation by including an inertial navigation system (INS) to accurately measure rotation. Experiments on both a phantom containing an image of human skin (palm) as well as actual human upper extremity (fingers, palm, and wrist) validate the effectiveness of our approach. We have also developed a real-time 3D interactive visualization system that superimposes the ultrasound data within the anatomical context of the exterior of the patient, to permit accurate anatomic localization of ultrasound data. The combination of the proposed tracking approach and the visualization system may have broad implications for ultrasound imaging, permitting the compilation of volumetric ultrasound data as the 2D probe is moved, as well as comparison of real-time ultrasound scans registered with previous scans from the same anatomical location. In a broader sense, tools that self-locate by viewing the patient’s exterior could have broad beneficial impact on clinical medicine

    Modeling Hydrophobic Effects at different lengthscales

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    Understanding hydrophobic effects at different length scales is relevant to many complex and poorly understood everyday phenomena in materials science and biology. In this thesis, a variety of theory/computational methods in statistical physics and statistical mechanics are used to address three separated, but interconnected problems: (1) How solvation free energy scales with a partical size that is charged? This problem has never been attempted to solve before despite its immense importance in colloidal and protein solutions (J. Wang, D. Bratko, K. Leung and A. Luzar, Hydrophobic hydration at different length-scales: manipulating the crossover by charges, to be submitted to J. Stat. Phys. (Special issue on Water and Associated Liquids)); (2) Can onset to capillary evaporation, seen in some protein complexes with large hydrophobic areas be predicted in a simple way? A simple coarse-grained model of water/protein system, which is developed here shows the conditions for wet and dry hydrophobic protein cavities, and is able to reproduce all atom simulation results. The method should serve as an intermediate step between the initial screening of protein hydrophobic cavities and expensive molecular simulations (J. Wang, S. Kudesia, and A. Luzar, Computational probe of dewetting events in protein systems, in preparation for submission to J. Phys. Chem. B); (3) How to predicts hydrophobicity of a mixed surface from the knowledge of its pure constituents? To this end, wetting free energy on synthetic and biological heterogeneous surfaces is studied. Two distinct mechanisms responsible for their non-additivity have been identified in each case (J. Wang, D. Bratko and A. Luzar, Probing surface tension additivity on heterogenous surfaces: a molecular approach, Proc. Natl. Acad. Sci, under revision

    Enhancing the resilience of the power system to accommodate the construction of the new power system: key technologies and challenges

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    The increasingly frequent extreme events pose a serious threat to the resilience of the power system. At the same time, the power grid is transforming into a new type of clean and low-carbon power system due to severe environmental issues. The system shows strong randomness with a high proportion of renewable energy, which has increased the difficulty of maintaining the safe and stable operation of the power system. Therefore, it is urgent to improve the resilience of the new power system. This paper first elaborates on the concept of power system resilience, listing the characteristics of new power systems and their impact on grid resilience. Secondly, the evaluation methods for resilient power grids are classified into two categories, and measures to improve the resilience of the new power system are reviewed from various stages of disasters. Then, the critical technologies for improving the resilience of the new power system are summarized. Finally, the prospective research directions for new power system resilience enhancement are expounded

    Topological Edge Transport in Twisted Double-Bilayer Graphene

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    Topological insulators realized in materials with strong spin-orbit interactions challenged the long-held view that electronic materials are classified as either conductors or insulators. The emergence of controlled, two-dimensional moire patterns has opened new vistas in the topological materials landscape. Here we report on evidence, obtained by combining thermodynamic measurements, local and non-local transport measurements, and theoretical calculations, that robust topologically non-trivial, valley Chern insulators occur at charge neutrality in twisted double-bilayer graphene (TDBG). These time reversal-conserving valley Chern insulators are enabled by valley-number conservation, a symmetry that emerges from the moir\'e pattern. The thermodynamic gap extracted from chemical potential measurements proves that TDBG is a bulk insulator under transverse electric field, while transport measurements confirm the existence of conducting edge states. A Landauer-Buttiker analysis of measurements on multi-terminal samples allows us to quantitatively assess edge state scattering and demonstrate that it does not destroy the edge states, leaving the bulk-boundary correspondence largely intact

    Intracoronary artery retrograde thrombolysis combined with percutaneous coronary interventions for ST-segment elevation myocardial infarction complicated with diabetes mellitus: A case report and literature review

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    BackgroundThe management of a large thrombus burden in patients with acute myocardial infarction and diabetes is still a worldwide problem.Case presentationA 74-year-old Chinese woman presented with ST-segment elevation myocardial infarction (STEMI) complicated with diabetes mellitus and hypertension. Angiography revealed massive thrombus formation in the mid-segment of the right coronary artery leading to vascular occlusion. The sheared balloon was placed far from the occlusion segment and urokinase (100,000 u) was administered for intracoronary artery retrograde thrombolysis, and thrombolysis in myocardial infarction (TIMI) grade 3 blood flow was restored within 7 min. At last, one stent was accurately implanted into the culprit’s vessel. No-reflow, coronary slow flow, and reperfusion arrhythmia were not observed during this process.ConclusionIntracoronary artery retrograde thrombolysis (ICART) can be effectively and safely used in patients with STEMI along with diabetes mellitus and hypertension, even if the myocardial infarction exceeds 12 h (REST or named ICART ClinicalTrials.gov number, ChiCTR1900023849)
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