366 research outputs found
A Review of the differences in Written Expressions between English and Chinese from the Perspective of Contrastive Analysis
Written expression plays an important role in students\u27 English learning and has always been a weak part in English teaching. In daily learning, the differences between mother tongue and second language inevitably have an impact on students\u27 writing. This paper aims to use contrastive analysis to explore the differences in lexical, syntactic, and discourse levels between English and Chinese writing, and proposes relevant teaching suggestions based on these, so as to improve students\u27 English writing level and teachers\u27 writing teaching level
Monitoring brain development of chick embryos in vivo using 3.0 T MRI: subdivision volume change and preliminary structural quantification using DTI
BACKGROUND: Magnetic resonance imaging (MRI) has many advantages in the research of in vivo embryonic brain development, specifically its noninvasive aspects and ability to avoid skeletal interference. However, few studies have focused on brain development in chick, which is a traditional animal model in developmental biology. We aimed to serially monitor chick embryo brain development in vivo using 3.0 T MRI. METHODS: Ten fertile Hy-line white eggs were incubated and seven chick embryo brains were monitored in vivo and analyzed serially from 5 to 20 days during incubation using 3.0 T MRI. A fast positioning sequence was pre-scanned to obtain sagittal and coronal brain planes corresponding to the established atlas. T2-weighted imaging (T2WI) was performed for volume estimation of the whole brain and subdivision (telencephalon, cerebellum, brainstem, and lateral ventricle [LV]); diffusion tensor imaging (DTI) was used to reflect the evolution of neural bundle structures. RESULTS: The chick embryos’ whole brain and subdivision grew non-linearly over time; the DTI fractional anisotropy (FA) value within the telencephalon increased non-linearly as well. All seven scanned eggs hatched successfully. CONCLUSIONS: MRI avoids embryonic sacrifice in a way that allows serial monitoring of longitudinal developmental processes of a single embryo. Feasibility for analyzing subdivision of the brain during development, and adding structural information related to neural bundles, makes MRI a powerful tool for exploring brain development
Modeling the Energy Performance of Event-Driven Wireless Sensor Network by Using Static Sink and Mobile Sink
Wireless Sensor Networks (WSNs) designed for mission-critical applications suffer from limited sensing capacities, particularly fast energy depletion. Regarding this, mobile sinks can be used to balance the energy consumption in WSNs, but the frequent location updates of the mobile sinks can lead to data collisions and rapid energy consumption for some specific sensors. This paper explores an optimal barrier coverage based sensor deployment for event driven WSNs where a dual-sink model was designed to evaluate the energy performance of not only static sensors, but Static Sink (SS) and Mobile Sinks (MSs) simultaneously, based on parameters such as sensor transmission range r and the velocity of the mobile sink v, etc. Moreover, a MS mobility model was developed to enable SS and MSs to effectively collaborate, while achieving spatiotemporal energy performance efficiency by using the knowledge of the cumulative density function (cdf), Poisson process and M/G/1 queue. The simulation results verified that the improved energy performance of the whole network was demonstrated clearly and our eDSA algorithm is more efficient than the static-sink model, reducing energy consumption approximately in half. Moreover, we demonstrate that our results are robust to realistic sensing models and also validate the correctness of our results through extensive simulations
Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients.
Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB
CURLS: Causal Rule Learning for Subgroups with Significant Treatment Effect
In causal inference, estimating heterogeneous treatment effects (HTE) is
critical for identifying how different subgroups respond to interventions, with
broad applications in fields such as precision medicine and personalized
advertising. Although HTE estimation methods aim to improve accuracy, how to
provide explicit subgroup descriptions remains unclear, hindering data
interpretation and strategic intervention management. In this paper, we propose
CURLS, a novel rule learning method leveraging HTE, which can effectively
describe subgroups with significant treatment effects. Specifically, we frame
causal rule learning as a discrete optimization problem, finely balancing
treatment effect with variance and considering the rule interpretability. We
design an iterative procedure based on the minorize-maximization algorithm and
solve a submodular lower bound as an approximation for the original.
Quantitative experiments and qualitative case studies verify that compared with
state-of-the-art methods, CURLS can find subgroups where the estimated and true
effects are 16.1% and 13.8% higher and the variance is 12.0% smaller, while
maintaining similar or better estimation accuracy and rule interpretability.
Code is available at https://osf.io/zwp2k/.Comment: 12 pages, 3 figure
Multimodal Identification of Alzheimer's Disease: A Review
Alzheimer's disease is a progressive neurological disorder characterized by
cognitive impairment and memory loss. With the increasing aging population, the
incidence of AD is continuously rising, making early diagnosis and intervention
an urgent need. In recent years, a considerable number of teams have applied
computer-aided diagnostic techniques to early classification research of AD.
Most studies have utilized imaging modalities such as magnetic resonance
imaging (MRI), positron emission tomography (PET), and electroencephalogram
(EEG). However, there have also been studies that attempted to use other
modalities as input features for the models, such as sound, posture,
biomarkers, cognitive assessment scores, and their fusion. Experimental results
have shown that the combination of multiple modalities often leads to better
performance compared to a single modality. Therefore, this paper will focus on
different modalities and their fusion, thoroughly elucidate the mechanisms of
various modalities, explore which methods should be combined to better harness
their utility, analyze and summarize the literature in the field of early
classification of AD in recent years, in order to explore more possibilities of
modality combinations
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