Investigation of Metal Oxide/Carbon Nano Material as Anode for High Capacity Lithium-ion Cells

NASA is developing high specific energy and high specific capacity lithium-ion battery (LIB) technology for future NASA missions. Current state-of-art LIBs have issues in terms of safety and thermal stability, and are reaching limits in specific energy capability based on the electrochemical materials selected. For example, the graphite anode has a limited capability to store Li since the theoretical capacity of graphite is 372 mAh/g. To achieve higher specific capacity and energy density, and to improve safety for current LIBs, alternative advanced anode, cathode, and electrolyte materials are pursued under the NASA Advanced Space Power System Project. In this study, the nanostructed metal oxide, such as Fe2O3 on carbon nanotubes (CNT) composite as an LIB anode has been investigated

Panoramic mosaics from Chang’E-3 PCAM images at Point A

This paper presents a unique approach for panoramic mosaics based on Moon surface images from the Chang’E-3 (CE-3) mission, with consideration of the exposure time and external illumination changes in CE-3 Panoramic Camera (PCAM) imaging. The engineering implementation involves algorithms of image feature points extraction by using Speed-Up Robust Features (SURF), and a newly defined measure is used to obtain the corresponding points in feature matching. Then, the transformation matrix is calculated and optimized between adjacent images by the Levenberg–Marquardt algorithm. Finally, an image is reconstructed by using a fade-in-fade-out method based on linear interpolation to achieve a seamless mosaic. The developed algorithm has been tested with CE-3 PCAM images at Point A (one of the rover sites where the rover is separated from the lander). This approach has produced accurate mosaics from CE-3 PCAM images, as is indicated by the value of the Peak Signal to Noise Ratio (PSNR), which is greater than 31 dB between the overlapped region of the images before and after fusion

Efficacy and safety of anlotinib in patients with advanced colorectal cancer and analysis of prognostic factors

Anlotinib, as the new RTK inhibitor molecule, has gained significant interest among researchers in drug development targeting tumors. In this study, we investigated the efficacy and safety of anlotinib in patients with advanced colorectal cancer and analyzed the prognostic factors. A total of 116 patients with advanced colorectal cancer who were treated in the oncology center of our hospital from March 2018 to March 2019 were selected. All patients were divided into a control group and an observation group according to the random number table method, with 58 cases in each group. The patients in the group were given docetaxel treatment, and the observer patients were given anlotinib treatment on this basis. The short-term efficacy, disease control rate, tumor progression time, median survival time and 1-year survival rate of the two groups after treatment were compared; The incidence of adverse reactions during treatment in the two groups; Kaplan-Meier method was used to analyze the prognostic factors of colorectal cancer patients. The total effective rate of patients in the observation group after treatment with anlotinib in the near future was 44.83%, which was significantly higher than 25.86% in the control group, the difference was statistically significant. The disease control rate and 1-year survival rate of the observation group after treatment with anlotinib were significantly higher than the control group, the difference was statistically significant, and the tumor progression time and survival time of the observation group were significantly longer than the control group. There was no significant difference in the total incidence of adverse reactions such as diarrhea, nausea and vomiting, leukopenia, thrombocytopenia, oral mucositis between the two groups of patients during treatment. Kaplan-Meier method analysis found that age, treatment plan, lymph node metastasis, and residual tumor diameter are all risk factors affecting the prognosis of colorectal cancer patients

Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation

Nonhealing diabetic wounds are common complications for diabetic patients. Because chronic hypoxia prominently delays wound healing, sustained oxygenation to alleviate hypoxia is hypothesized to promote diabetic wound healing. However, sustained oxygenation cannot be achieved by current clinical approaches, including hyperbaric oxygen therapy. Here, we present a sustained oxygenation system consisting of oxygen-release microspheres and a reactive oxygen species (ROS)-scavenging hydrogel. The hydrogel captures the naturally elevated ROS in diabetic wounds, which may be further elevated by the oxygen released from the administered microspheres. The sustained release of oxygen augmented the survival and migration of keratinocytes and dermal fibroblasts, promoted angiogenic growth factor expression and angiogenesis in diabetic wounds, and decreased the proinflammatory cytokine expression. These effects significantly increased the wound closure rate. Our findings demonstrate that sustained oxygenation alone, without using drugs, can heal diabetic wounds

Long‐lasting goodshielding at the equatorial ionosphere

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95323/1/jgra20828.pd

Efficacy and safety of anlotinib in patients with advanced colorectal cancer and analysis of prognostic factors

740-744Anlotinib, as the new RTK inhibitor molecule, has gained significant interest among researchers in drug development targeting tumors. In this study, we investigated the efficacy and safety of anlotinib in patients with advanced colorectal cancer and analyzed the prognostic factors. A total of 116 patients with advanced colorectal cancer who were treated in the oncology center of our hospital from March 2018 to March 2019 were selected. All patients were divided into a control group and an observation group according to the random number table method, with 58 cases in each group. The patients in the group were given docetaxel treatment, and the observer patients were given anlotinib treatment on this basis. The short-term efficacy, disease control rate, tumor progression time, median survival time and 1-year survival rate of the two groups after treatment were compared; The incidence of adverse reactions during treatment in the two groups; Kaplan-Meier method was used to analyze the prognostic factors of colorectal cancer patients. The total effective rate of patients in the observation group after treatment with anlotinib in the near future was 44.83%, which was significantly higher than 25.86% in the control group, the difference was statistically significant. The disease control rate and 1-year survival rate of the observation group after treatment with anlotinib were significantly higher than the control group, the difference was statistically significant, and the tumor progression time and survival time of the observation group were significantly longer than the control group. There was no significant difference in the total incidence of adverse reactions such as diarrhea, nausea and vomiting, leukopenia, thrombocytopenia, oral mucositis between the two groups of patients during treatment. Kaplan-Meier method analysis found that age, treatment plan, lymph node metastasis, and residual tumor diameter are all risk factors affecting the prognosis of colorectal cancer patients

A consensus linkage map of the grass carp (Ctenopharyngodon idella) based on microsatellites and SNPs

<p>Abstract</p> <p>Background</p> <p>Grass carp (<it>Ctenopharyngodon idella</it>) belongs to the family Cyprinidae which includes more than 2000 fish species. It is one of the most important freshwater food fish species in world aquaculture. A linkage map is an essential framework for mapping traits of interest and is often the first step towards understanding genome evolution. The aim of this study is to construct a first generation genetic map of grass carp using microsatellites and SNPs to generate a new resource for mapping QTL for economically important traits and to conduct a comparative mapping analysis to shed new insights into the evolution of fish genomes.</p> <p>Results</p> <p>We constructed a first generation linkage map of grass carp with a mapping panel containing two F1 families including 192 progenies. Sixteen SNPs in genes and 263 microsatellite markers were mapped to twenty-four linkage groups (LGs). The number of LGs was corresponding to the haploid chromosome number of grass carp. The sex-specific map was 1149.4 and 888.8 cM long in females and males respectively whereas the sex-averaged map spanned 1176.1 cM. The average resolution of the map was 4.2 cM/locus. BLAST searches of sequences of mapped markers of grass carp against the whole genome sequence of zebrafish revealed substantial macrosynteny relationship and extensive colinearity of markers between grass carp and zebrafish.</p> <p>Conclusions</p> <p>The linkage map of grass carp presented here is the first linkage map of a food fish species based on co-dominant markers in the family Cyprinidae. This map provides a valuable resource for mapping phenotypic variations and serves as a reference to approach comparative genomics and understand the evolution of fish genomes and could be complementary to grass carp genome sequencing project.</p