757 research outputs found
How volatilities nonlocal in time affect the price dynamics in complex financial systems
What is the dominating mechanism of the price dynamics in financial systems
is of great interest to scientists. The problem whether and how volatilities
affect the price movement draws much attention. Although many efforts have been
made, it remains challenging. Physicists usually apply the concepts and methods
in statistical physics, such as temporal correlation functions, to study
financial dynamics. However, the usual volatility-return correlation function,
which is local in time, typically fluctuates around zero. Here we construct
dynamic observables nonlocal in time to explore the volatility-return
correlation, based on the empirical data of hundreds of individual stocks and
25 stock market indices in different countries. Strikingly, the correlation is
discovered to be non-zero, with an amplitude of a few percent and a duration of
over two weeks. This result provides compelling evidence that past volatilities
nonlocal in time affect future returns. Further, we introduce an agent-based
model with a novel mechanism, that is, the asymmetric trading preference in
volatile and stable markets, to understand the microscopic origin of the
volatility-return correlation nonlocal in time.Comment: 16 pages, 7 figure
Word Embedding based Correlation Model for Question/Answer Matching
With the development of community based question answering (Q&A) services, a
large scale of Q&A archives have been accumulated and are an important
information and knowledge resource on the web. Question and answer matching has
been attached much importance to for its ability to reuse knowledge stored in
these systems: it can be useful in enhancing user experience with recurrent
questions. In this paper, we try to improve the matching accuracy by overcoming
the lexical gap between question and answer pairs. A Word Embedding based
Correlation (WEC) model is proposed by integrating advantages of both the
translation model and word embedding, given a random pair of words, WEC can
score their co-occurrence probability in Q&A pairs and it can also leverage the
continuity and smoothness of continuous space word representation to deal with
new pairs of words that are rare in the training parallel text. An experimental
study on Yahoo! Answers dataset and Baidu Zhidao dataset shows this new
method's promising potential.Comment: 8 pages, 2 figure
Scaling in directed dynamical small-world networks with random responses
A dynamical model of small-world network, with directed links which describe
various correlations in social and natural phenomena, is presented. Random
responses of every site to the imput message are introduced to simulate real
systems. The interplay of these ingredients results in collective dynamical
evolution of a spin-like variable S(t) of the whole network. In the present
model, global average spreading length \langel L >_s and average spreading time
_s are found to scale as p^-\alpha ln N with different exponents.
Meanwhile, S behaves in a duple scaling form for N>>N^*: S ~ f(p^-\beta
q^\gamma t'_sc), where p and q are rewiring and external parameters, \alpha,
\beta, \gamma and f(t'_sc) are scaling exponents and universal functions,
respectively. Possible applications of the model are discussed.Comment: 4 pages, 6 Figure
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Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus.
Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection. Staphylococcal accessory regulator A (SarA), a global virulence regulator, plays a critical role in pathogenesis and β-lactam antibiotic resistance in Staphylococcus aureus. Hypericin is believed to act as an antibiotic, antidepressant, antiviral and non-specific kinase inhibitor. In the current study, we investigated the impact of hypericin on β-lactam antibiotics susceptibility and mechanism(s) of its activity. We demonstrated that hypericin significantly decreased the minimum inhibitory concentrations of β-lactam antibiotics (e.g., oxacillin, cefazolin and nafcillin), biofilm formation and fibronectin binding in MRSA strain JE2. In addition, hypericin significantly reduced sarA expression, and subsequently decreased mecA, and virulence-related regulators (e.g., agr RNAⅢ) and genes (e.g., fnbA and hla) expression in the studied MRSA strain. Importantly, the in vitro synergistic effect of hypericin with β-lactam antibiotic (e.g., oxacillin) translated into in vivo therapeutic outcome in a murine MRSA bacteremia model. These findings suggest that hypericin plays an important role in abrogation of β-lactam resistance against MRSA through sarA inhibition, and may allow us to repurpose the use of β-lactam antibiotics, which are normally ineffective in the treatment of MRSA infections (e.g., oxacillin)
Fabrication and Characterization of Al/NiO Energetic Nanomultilayers
The redox reaction between Al and metallic oxide has its advantage compared with intermetallic reaction and Al/NiO nanomutlilayers are a promising candidate for enhancing the performance of energetic igniter. Al/NiO nanomutlilayers with different modulation periods are prepared on alumina substrate by direct current (DC) magnetron sputtering. The thicknesses of each period are 250 nm, 500 nm, 750 nm, 1000 nm, and 1500 nm, respectively, and the total thickness is 3 μm. The X-ray diffraction (XRD) and scanning electron microscope (SEM) results of the as-deposited Al/NiO nanomutlilayers show that the NiO films are amorphous and the layered structures are clearly distinguished. The X-ray photoelectron spectroscopy (XPS) demonstrates that the thickness of Al2O3 increases on the side of Al monolayer after annealing at 450°C. The thermal diffusion time becomes greater significantly as the amount of thermal boundary conductance across the interfaces increases with relatively smaller modulation period. Differential scanning calorimeter (DSC) curve suggests that the energy release per unit mass is below the theoretical heat of the reaction due to the nonstoichiometric ratio between Al and NiO and the presence of impurities
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