Temperature Dependent Motion of a Massive Quantum Particle

We report model calculations of the time-dependent internal energy and entropy for a single quasi-free massive quantum particle at a constant temperature. We show that the whole process started from a fully coherent quantum state to thermodynamic equilibrium can be understood, based on statistics of diffracted matter waves. As a result of thermal interaction between the particle and its surroundings, the motion of the particle shows new feature.Comment: 3 figure

Proteomic changes in response to lipin1 overexpression in 293T human renal epithelial cells

466-474Lipin1, a member of the lipin family, serves as a phospholipid phosphatase or a co-transcriptional regulator in lipid metabolism. Recent studies also show that lipin1 is involved in many other cellular metabolism processes. However, the clear regulatory mechanism for lipin1 is unknown. The 293T human renal epithelial cell line represents a commonly used and well established expression system for recombinant proteins. Herein, we used two-dimensional polyacrylamide gel electrophoresis (2D-GE) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) to explore the changes in protein expression induced by lipin1 overexpression in 293T cells. Western blotting was used to confirm one of the expression changes of related proteins. Subsequently, the function and relationship of these proteins were analyzed by bioinformatics approach. By using 2D-PAGE, approximately 152 proteins were separated and eleven proteins were found to be significantly affected by lipin1 overexpression compared to the control. Among them, three proteins (eEF-1B γ, CCT1 and CCT3) were up-regulated and other eight proteins (NDKA, Stathmin, HNRNP A1, TK, KRT1, PKM, RanBP1 and LDHB) were down-regulated. These proteins were successfully identified with peptide mass fingerprinting using MALDI-TOF-MS after in-gel trypsin digestion. The bioinformatic analysis showed that these proteins are classified into seven protein species, including transferase, cleavage enzyme, cytoskeleton protein, chaperone protein, regulatory protein, structural protein and oxidoreductase. The results highlight the potential roles of lipin1 involved in many cellular metabolism processes, including myelin synthesis, extracellular domain formation, membrane bound vesicle synthesis and companion protein T complex synthesis

Proteomic changes in response to lipin1 overexpression in 293T human renal epithelial cells

Lipin1, a member of the lipin family, serves as a phospholipid phosphatase or a co-transcriptional regulator in lipid metabolism. Recent studies also show that lipin1 is involved in many other cellular metabolism processes. However, the clear regulatory mechanism for lipin1 is unknown. The 293T human renal epithelial cell line represents a commonly used and well established expression system for recombinant proteins. Herein, we used two-dimensional polyacrylamide gel electrophoresis (2D-GE) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) to explore the changes in protein expression induced by lipin1 overexpression in 293T cells. Western blotting was used to confirm one of the expression changes of related proteins. Subsequently, the function and relationship of these proteins were analyzed by bioinformatics approach. By using 2D-PAGE, approximately 152 proteins were separated and eleven proteins were found to be significantly affected by lipin1 overexpression compared to the control. Among them, three proteins (eEF-1B γ, CCT1 and CCT3) were up-regulated and other eight proteins (NDKA, Stathmin, HNRNP A1, TK, KRT1, PKM, RanBP1 and LDHB) were down-regulated. These proteins were successfully identified with peptide mass fingerprinting using MALDI-TOF-MS after in-gel trypsin digestion. The bioinformatic analysis showed that these proteins are classified into seven protein species, including transferase, cleavage enzyme, cytoskeleton protein, chaperone protein, regulatory protein, structural protein and oxidoreductase. The results highlight the potential roles of lipin1 involved in many cellular metabolism processes, including myelin synthesis, extracellular domain formation, membrane bound vesicle synthesis and companion protein T complex synthesis

Building quantum neural networks based on swap test

Artificial neural network, consisting of many neurons in different layers, is an important method to simulate humain brain. Usually, one neuron has two operations: one is linear, the other is nonlinear. The linear operation is inner product and the nonlinear operation is represented by an activation function. In this work, we introduce a kind of quantum neuron whose inputs and outputs are quantum states. The inner product and activation operator of the quantum neurons can be realized by quantum circuits. Based on the quantum neuron, we propose a model of quantum neural network in which the weights between neurons are all quantum states. We also construct a quantum circuit to realize this quantum neural network model. A learning algorithm is proposed meanwhile. We show the validity of learning algorithm theoretically and demonstrate the potential of the quantum neural network numerically.Comment: 10 pages, 13 figure

In-situ tuning of catalytic activity by thermoelectric effect for ethylene oxidation

Thermoelectric material BiCuSeO used as a support and promoter for catalytic ethylene oxidation is reported here. The catalytic activity on the continuous and non-continuous catalyst Pt supported on BiCuSeO was observed to be promoted in-situ by a thermoelectric Seebeck voltage generated by the temperature gradient across the material. It is also shown this thermoelectric promotion of catalysis enabled the thermoelectric material BiCuSeO itself to be highly catalytic active for ethylene oxidation. A good linear relationship between the logarithm of the reaction rate and the thermoelectric Seebeck voltage was observed. This thermoelectric promotion of catalysis is attributed to the change of work function of the catalyst surface, accompanied by a charge transfer from the bulk to the surface due to the thermoelectric effect