Efficient chain structure for high-utility sequential pattern mining

High-utility sequential pattern mining (HUSPM) is an emerging topic in data mining, which considers both utility and sequence factors to derive the set of high-utility sequential patterns (HUSPs) from the quantitative databases. Several works have been presented to reduce the computational cost by variants of pruning strategies. In this paper, we present an efficient sequence-utility (SU)-chain structure, which can be used to store more relevant information to improve mining performance. Based on the SU-Chain structure, the existing pruning strategies can also be utilized here to early prune the unpromising candidates and obtain the satisfied HUSPs. Experiments are then compared with the state-of-the-art HUSPM algorithms and the results showed that the SU-Chain-based model can efficiently improve the efficiency performance than the existing HUSPM algorithms in terms of runtime and number of the determined candidates

Increased Levels of C1q in the prefrontal cortex of adult offspring after maternal immune activation: Prevention by 7,8-dihydroxyflavone

Objective: Prenatal infection is implicated in the etiology of schizophrenia. The objective of this paper is to study the role of complement protein C1q in the psychosis of adult offspring after maternal immune activation (MIA). In addition, effect of 7,8-dihydroxyflavone (7,8-DHF: A tropomyosin receptor kinase B [TrkB] agonist) was also examined. Methods: Western blot analysis of C1q in the brain regions from adult offspring after prenatal poly(I:C) (5.0 mg/kg/day from E12 to E17) exposure was performed. 7,8-DHF or vehicle was given from 4 to 8-weeks old. Results: Expression of C1q in the prefrontal cortex (PFC) of adult offspring from poly(I:C)-Treated pregnant mice was significantly higher than that of control group. Early treatment with 7,8-DHF during juvenile and adolescent stages could prevent an increase of C1q in the PFC of adult offspring after MIA. Conclusion: Therefore, it is likely that increased C1q expression in the frontal cortex may play a role in the behavioral abnormalities of adult offspring after MIA. Furthermore, supplementation with a TrkB agonist such as 7,8-DHF during the prodromal stage may have prophylactic effects on the behavioral abnormalities after MIA

FRIOD: a deeply integrated feature-rich interactive system for effective and efficient outlier detection

In this paper, we propose an novel interactive outlier detection system called feature-rich interactive outlier detection (FRIOD), which features a deep integration of human interaction to improve detection performance and greatly streamline the detection process. A user-friendly interactive mechanism is developed to allow easy and intuitive user interaction in all the major stages of the underlying outlier detection algorithm which includes dense cell selection, location-aware distance thresholding, and final top outlier validation. By doing so, we can mitigate the major difficulty of the competitive outlier detection methods in specifying the key parameter values, such as the density and distance thresholds. An innovative optimization approach is also proposed to optimize the grid-based space partitioning, which is a critical step of FRIOD. Such optimization fully considers the high-quality outliers it detects with the aid of human interaction. The experimental evaluation demonstrates that FRIOD can improve the quality of the detected outliers and make the detection process more intuitive, effective, and efficient

Observation of electric current induced by optically injected spin current

A normally incident light of linear polarization injects a pure spin current in a strip of 2-dimensional electron gas with spin-orbit coupling. We report observation of an electric current with a butterfly-like pattern induced by such a light shed on the vicinity of a crossbar shaped InGaAs/InAlAs quantum well. Its light polarization dependence is the same as that of the spin current. We attribute the observed electric current to be converted from the optically injected spin current caused by scatterings near the crossing. Our observation provides a realistic technique to detect spin currents, and opens a new route to study the spin-related science and engineering in semiconductors.Comment: 15 pages, 4 figure