Neoliberal extractivism and rural resistance: the anti-mining movement in the Peruvian Northern Highlands, Cajamarca (2011-2013)

This dissertation examines the political prospects of rural subaltern groups in the era of neoliberal globalisation by engaging with the ‘death of the peasantry’ debates. To achieve this, it concentrates on rural resistance in the northern highlands of Peru, Cajamarca, against ‘new mineral extraction’ by multinational capital in the form of Minera Yanacocha S.A. (MYSA), with a theoretical framework of critical geography on transnational activism. In particular, the dissertation devotes attention to the massive mobilisations against MYSA’s Conga mining project between 2011 and 2013. The dispossession and disempowerment of the peasantry have been highlighted as the accumulation of global capital has intensified alongside the implementation of market-led development models around the globe. In the 1990s, the extraction and export of abundant natural resources was promoted as a ‘new development alternative’. In tandem with the unprecedented width and depth of resource extraction, the continent has become witness to increasing incidences of struggles led by local communities, particularly in the countryside. Recent Peruvian economic growth has been boosted by a ‘new mining boom’. Simultaneously, many Peruvians are protesting against mining activities, particularly due to their negative social and environmental impact. Cajamarca is one obvious example where neoliberal mineral extraction has generated a series of local struggles since the arrival of MYSA in 1993. The asymmetrical power of multinational capital vis-à-vis campesinos stands out in the context of the emphasis of the central government on ‘national development’ based on natural resource extraction. Against this backdrop, this dissertation examines the re-articulation of rural subjectivities and the political possibilities in their ‘networked form of resistance’, instead of focusing on the fragmentation, powerlessness and passivity of subaltern groups in the face of global capital power. Economic reductionism restricts our understanding of neoliberal globalisation to the exploitation of global capital vs. dispossession of local communities. Following Doreen Massey’s relational geographical approach, the dissertation maintains that it is relevant to understand the ‘relational content’ of global capital mobility and complex dynamics of resistance. In addition, the dualistic framework of geography and power which is based on an essentialist geographical understanding of the spatial (i.e. space/place; powerful global and powerless local) tends to regard local resistance as ‘reactionary’ place-based struggle. Instead, the dissertation focuses on the ‘interconnectedness’ of subaltern groups. It argues that diverse social groups shape what Featherstone terms ‘prefigurative solidarity’ around ‘maps of grievance’, via political resistance. In this process, a political identity is constructed in order to bring neoliberal globalisation into contestation

Dual Therapy with Cidofovir and Mirtazapine for Progressive Multifocal Leukoencephalopathy in a Sarcoidosis Patient

Background: Progressive multifocal leukoencephalopathy (PML) is a demyelinating central nervous system disease caused by JC virus (JCV) reactivation in immunocompromised patients. The disease course of PML is often progressive, fatal and at present, there are few reports on successful treatment outcomes. Case Report: A 45-year-old man with systemic sarcoidosis presented with rapidly progressive dementia and right hemiparesis. The patient was diagnosed with PML as confirmed via brain biopsy and JCV PCR. With a combination treatment of cidofovir and mirtazapine, there was significant improvement of neurological symptoms without measurable functional deficit. Conclusion: This case suggests that dual therapy with cidofovir and mirtazapine might be an effective treatment option in PML patients with sarcoidosis

Experimental investigations on the characteristics of snow accretion using the EMU-320 model train

This paper presents a snow accretion test conducted in a climate wind tunnel to investigate the icing process on a model train. The model used within this experiment was the cleaned-up and 2/3-scaled version of EMU-320, which is a high-speed train in Korea. The model was designed without an electronic power source or heat source so that the wheels did not rotate and snow accretion on the model did not occur due to heat sources. To investigate snow accretion, four cases with different ambient temperatures were considered in the climate wind tunnel on Rail Tec Arsenal. Before analyzing the snow accretion on the train, the snow flux and liquid water content of snow were measured so that they could be used as the input conditions for the simulation and to ensure the analysis of the icing process was based on the characteristics of the snow. Both qualitative and quantitative data were obtained, whereby photographs was used for qualitative analysis, and the density of the snow sample and the thickness of snow accreted on the model were used for quantitative analysis. Based on the visual observations, it was deduced that as the ambient temperature increased, the range of the snow accreted was broader. The thickness of snow accreted on the model nose was the largest on the upper and lower part at -3 oC, and on the middle part at -5 oC. Additionally, the cross section of snow accreted was observed to be trench-like. Similar icing processes were observed to occur on the slope of nose. Snow accreted on all components of the bogie, and for all cases, the thickness of snow at wheel was the largest at an arc angle of 40 to 70 o. These detailed data of experimental conditions can be applied as an input to simulations to improve simulations of ice conditions. Thus, they can facilitate the development of appropriate anti-icing designs for trainsComment: 31 pages, 23 Figures, 8 Table

Brain-Driven Representation Learning Based on Diffusion Model

Interpreting EEG signals linked to spoken language presents a complex challenge, given the data's intricate temporal and spatial attributes, as well as the various noise factors. Denoising diffusion probabilistic models (DDPMs), which have recently gained prominence in diverse areas for their capabilities in representation learning, are explored in our research as a means to address this issue. Using DDPMs in conjunction with a conditional autoencoder, our new approach considerably outperforms traditional machine learning algorithms and established baseline models in accuracy. Our results highlight the potential of DDPMs as a sophisticated computational method for the analysis of speech-related EEG signals. This could lead to significant advances in brain-computer interfaces tailored for spoken communication

A Case of Congenital Common Bile Duct Web Treated with Balloon Dilation under Endoscopic Retrograde Cholangiopancreatography in a Young Child

Web in common bile duct (CBD web) is very rare. It is usually asymptomatic and detected incidentally during surgery for other causes in adults. It can be congenital or acquired, however congenital CBD web is extremely rare. Currently, despite its invasiveness and complications, endoscopic retrograde cholangiopancreatography (ERCP) is considered as a useful diagnostic and therapeutic modality in children with hepatobiliary pancreatic diseases as in adults. Herein we report a case of congenital CBD web presenting with acute pancreatitis and choledocholithiasis in a 4-year-old girl which was diagnosed and treated using balloon dilation under ERCP. After balloon dilation of the web, a common pancreatobiliary channel was observed. To the best of our knowledge, a case of congenital CBD web with pancreatobiliary junctional abnormality treated using ERCP in a child has not been reported to date

Phytohormone abscisic acid control RNA-dependent RNA polymerase 6 gene expression and post-transcriptional gene silencing in rice cells

RNA-dependent RNA polymerase 6 (RDR6) catalyses dsRNA synthesis for post-transcriptional gene silencing (PTGS)-associated amplification and the generation of endogeneous siRNAs involved in developmental determinations or stress responses. The functional importance of RDR6 in PTGS led us to examine its connection to the cellular regulatory network by analyzing the hormonal responses of RDR6 gene expression in a cultured cell system. Delivery of dsRNA, prepared in vitro, into cultured rice (Oryza sativa cv. Japonica Dongjin) cells successfully silenced the target isocitrate lyase (ICL) transcripts. Silencing was transient in the absence of abscisic acid (ABA), while it became persistent in the presence of ABA in growth medium. A transcription assay of the OsRDR6 promoter showed that it was positively regulated by ABA. OsRDR6-dependent siRNA(ICL) generation was also significantly up-regulated by ABA. The results showed that, among the five rice OsRDR isogenes, only OsRDR6 was responsible for the observed ABA-mediated amplification and silencing of ICL transcripts. We propose that ABA modulates PTGS through the transcriptional control of the OsRDR6 gene

Prevalence of sarcopenia and sarcopenic obesity in Korean adults: The Korean Sarcopenic Obesity Study (KSOS)

*Context:* Sarcopenic obesity (SO), a combination of excess weight and reduced muscle mass and/or strength, is suggested to be associated with an increased risk of adverse health outcomes. 
*Objectives:* To examine the prevalence and characteristics of Sarcopenic and SO defined by using different indices such as Appendicular Skeletal muscle Mass (ASM)/height^2^ and Skeletal Muscle Index (SMI (%): skeletal muscle mass (kg)/weight (kg) × 100) for Korean adults. 
*Methods:* 591 participants were recruited from the Korean Sarcopenic Obesity Study (KSOS) which is an ongoing prospective observational cohort study. Analysis was conducted in 526 participants (328 women, 198 men) who had complete data on body composition using Dual X-ray absorptiometry and computed tomography. 
*Results:* The prevalence of sarcopenia and SO increases with aging. Using two or more standard deviations (SD) of ASM/height^2^ below reference values from young, healthy adults as a definition of sarcopenia, the prevalence of sarcopenia and SO was 6.3% and 1.3% in men and 4.1% and 1.7% in women over 60 years of age. However, using two or more SD of SMI, the prevalence of sarcopenia and SO was 5.1% and 5.1% respectively in men and 14.2% and 12.5% respectively in women. As defined by SMI, subjects with SO had 3 times the risk of metabolic syndrome (OR = 3.03, 95% confidence interval (CI) = 1.26-7.26) and subjects with non-sarcopenic obesity had approximately 2 times the risk of metabolic syndrome (OR = 1.89, 95% CI = 1.18-3.02) compared with normal subjects. 
*Conclusion:* Obese subjects with relative sarcopenia were associated with a greater likelihood for metabolic syndrome. As Koreans were more obese and aging, the prevalence of SO and its impact on health outcomes are estimated to be rapidly grow. Further research is requested to establish the definition, cause and consequences of SO.
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Personality traits and emotional status affecting academic achievements of medical students: testifying mediating effect of learning strategies

Purpose The purpose of this study is to identify possible causal relationships among personality traits, emotional status, learning strategies, and academic achievements of medical students and to testify mediating effect of learning strategies in these relationships. Methods The study subjects are 424 medical students in the academic year of 2020 at the Gyeongsang National University, Jinju, Korea. Using the Multi-dimensional Learning Strategy Test-II, we assessed the students’ academic achievements with personality traits, emotional status, and learning strategies. This study employed Structural Equation Modelling to explore the causal relationships among the latent variables. Results In the path model, personality traits directly affected academic achievements (β=0.285, p<0.05) and indirectly affected academic achievements via emotional status (β=0.063, p<0.01) and via learning strategies (β=0.244, p<0.05), respectively. Further, personality traits indirectly affected academic achievements via emotional status first and learning strategies next (β=0.019, p<0.05). Personality traits indirectly affected academic achievements through three multiple paths in the model (β=0.326, p<0.05). Learning strategies partially mediated the relationship between personality traits and academic achievements as well as the relationship between emotional status and academic achievements of medical students. Conclusion Study findings proved constructing the causal relationships among personality traits, emotional status, learning strategies, and academic achievements of medical students, thus supporting our hypotheses. Early habits of self-regulated learning are essential for the successful academic achievements of medical students. Therefore, medical students should know how to regulate personality traits and control emotional status, significantly affecting learning strategies

Customized Energy Down-Shift using Iridium Complexes for Enhanced Performance of Polymer Solar Cells

School of Molecular Sciences(Chemistry)For the higher performance of polymer solar cells (PSCs), many researchers tried to develop new polymers that can absorb broader range of spectrum. However, there are some limits to absorb broader range with single donor. Therefore, multi donor systems and energy transfer systems have been researched. With two different donors it is easier to enhance absorption range. As a result, multi donor and energy transfer was successful to increase performance. However, the existing systems are applying polymer-polymer systems. When two different polymers are mixed, the compatibility between two polymers is critical to morphology of blend film. Also, in polymer-polymer energy transfer, the boundary between charge transfer and energy transfer is unclear. Therefore, for the first time, we developed customized iridium (Ir(III)) complexes, with Ir(III) complex incorporated into the active materials poly(thieno[3,4-b]-thiophene/benzodithiophene) (PTB7, amorphous) or poly(3-hexylthiophene) (P3HT, high crystalline) as energy donor additives. The Ir(III) complex with the 2-phenyl quinolone ligand energy donor increased the power conversion efficiency of the corresponding devices by approximately 20%. The enhancements are attributed to the improved molecular compatibility and energy level between the Ir(III) complex and the active materials, long F??rster resonance energy transfer radius, and high energy down-shift efficiency. Overall, we reveal Ir(III) complex additives for amorphous and highly crystalline polymer active materialsthese additives would enable efficient energy transfer in polymer solar cells, while retaining the desirable active layer morphology, thereby resulting in improved light absorption and conversion.ope