Brief Note Difficulties in Determining Factors that Influence Effective Groundwater Recharge in Ohio

Author Institution: COSI Academy, Center of Science and Industry ; US Geological SurveyAS part of a COSI Academy research project, data from a recent statewide analysis of effective groundwater recharge were reexamined by students to further discern relations between recharge and selected environmental characteristics of individual drainage basins: 1) location of the main stem of a river relative to coarse and fine surficial sediments and 2) influence of land use. Lack of sufficiently detailed data was the principal difficulty in most phases of the examination. Other than a potential relation between recharge and the percentages of agricultural and forested land, no relations were found in visual comparisons of mapped and tabulated data

Impactful Practice: Lessons Learned Through Ballooning Outreach

The goal of Bluegrass Community and Technical College’s (BCTC) Eclipse Outreach Ambassador Project was to get students across the Bluegrass excited and educated about the 2017 total solar eclipse. Several years ago the BalloonSat Project was started to provide hands-on earth and atmospheric science experiences to BCTC students. In linking the two initiatives, we allowed BCTC BalloonSat team members to continue learning to design, build, test, fly and retrieve balloon-borne payloads while using a novel method by which to engage local elementary and middle school students in learning more about and anticipating the upcoming eclipse. Eclipse practice flights carried payloads constructed by local K-12 STEM students. Balloon team members will discuss lessons learned in launch, flight, and recovery procedures, as well as, STEM outreach

High-efficiency frequency doubling of continuous-wave laser light

We report on the observation of high efficiency frequency doubling of 1550 nm continuous-wave laser light in a nonlinear cavity containing a periodically poled potassium titanyl phosphate crystal (PPKTP). The fundamental field had a power of 1.10 W and was converted into 1.05 W at 775 nm, yielding a total external conversion efficiency of (95 \pm 1)%. The latter value is based on the measured depletion of the fundamental field being consistent with the absolute values derived from numerical simulations. According to our model, the conversion efficiency achieved was limited by the non-perfect mode-matching into the nonlinear cavity and the pump power available. Our result shows that cavity-assisted frequency conversion based on PPKTP is well suited for low-decoherence frequency conversion of quantum states of light.Comment: 3 pages, 3 figure

Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects

Mental disorders are highly comorbid and occur together with physical diseases, which are often considered to arise from separate pathogenic pathways. We observed in alcohol-dependent patients increased serum activity of neutral sphingomyelinase. A genetic association analysis in 456,693 volunteers found associations of haplotypes of SMPD3 coding for NSM-2 (NSM) with alcohol consumption, but also with affective state, and bone mineralisation. Functional analysis in mice showed that NSM controls alcohol consumption, affective behaviour, and their interaction by regulating hippocampal volume, cortical connectivity, and monoaminergic responses. Furthermore, NSM controlled bone–brain communication by enhancing osteocalcin signalling, which can independently supress alcohol consumption and reduce depressive behaviour. Altogether, we identified a single gene source for multiple pathways originating in the brain and bone, which interlink disorders of a mental–physical co-morbidity trias of alcohol abuse—depression/anxiety—bone disorder. Targeting NSM and osteocalcin signalling may, thus, provide a new systems approach in the treatment of a mental–physical co-morbidity trias

Access to Difficult-to-reach Population Subgroups: A Family Midwife Based Home Visiting Service for Implementing Nutrition-related Preventive Activities - A Mixed Methods Explorative Study

Health and social inequality are tightly linked and still pose an important public health problem. However, vulnerable and disadvantaged populations are difficult to reach for health-related interventions. Given the long-lasting effects of an adverse, particular nutrition-related, intrauterine and neonatal environment on health development (perinatal programming), an early and easy access is essential for sustainable interventions. The goal of this explorative study was therefore to elucidate whether an existing access of family midwives (FMs) to families in need of support could be an option to implement effective public health and nutrition interventions. To that end three research objectives were formulated: (1) to determine whether a discernible impact of home visits by FMs can be described; (2) to identify subgroups among these families in need of more specific interventions; (3) to determine how relevant nutrition-related topics are for both FMs and the supported families. For addressing these objectives a mixed methods design was used: Routine documentation data from 295 families visited by a family midwife (FM) were analyzed (secondary analysis), and structured expert interviews with FMs were conducted and analyzed. Study reporting followed the STROBE (STrengthening the Reporting of OBservational studies in Epidemiology) statement. Based on the FMs reports, a significant improvement (p < 0.001) regarding psycho-social variables could be determined after the home visits. Single mothers, however, seemed to benefit less from the FMs service compared to their counterparts (p = 0.015). Nutritional counseling was demanded by 89% of the families during the home visits. In addition, nutrition-related topics were reported in the interviews to be of high interest to both families and the FMs. Based on the obtained results it is concluded that FMs home visits offer a promising access to vulnerable and disadvantaged families for implementing nutrition-related preventive activities

Absorption Measurements of Periodically Poled Potassium Titanyl Phosphate (PPKTP) at 775 nm and 1550 nm

The efficient generation of second-harmonic light and squeezed light requires non-linear crystals that have low absorption at the fundamental and harmonic wavelengths. In this work the photo-thermal self-phase modulation technique is exploited to measure the absorption coefficient of periodically poled potassium titanyl phosphate (PPKTP) at 1,550 nm and 775 nm. Themeasurement results are (84±40) ppm/cmand (127±24) ppm/cm, respectively. We conclude that the performance of state-of-the-art frequency doubling and squeezed light generation in PPKTP is not limited by absorption

Impactful Practice: Lessons Learned Through Ballooning Outreach

The goal of Bluegrass Community and Technical College’s (BCTC) Eclipse Outreach Ambassador Project was to get students across the Bluegrass excited and educated about the 2017 total solar eclipse. Several years ago the BalloonSat Project was started to provide hands-on earth and atmospheric science experiences to BCTC students. In linking the two initiatives, we allowed BCTC BalloonSat team members to continue learning to design, build, test, fly and retrieve balloon-borne payloads while using a novel method by which to engage local elementary and middle school students in learning more about and anticipating the upcoming eclipse. Eclipse practice flights carried payloads constructed by local K-12 STEM students. Balloon team members will discuss lessons learned in launch, flight, and recovery procedures, as well as, STEM outreach

Changes in clinical markers observed from pharmacist-managed cardiovascular risk reduction clinics in federally qualified health centers: A retrospective cohort study

Background Reductions in hemoglobin A1c (HbA1C) have been associated with improved cardiovascular outcomes and savings in medical expenditures. One public health approach has involved pharmacists within primary care settings. The objective was to assess change in HbA1C from baseline after 3–5 months of follow up in pharmacist-managed cardiovascular risk reduction (CVRR) clinics. Methods This retrospective cohort chart review occurred in eight pharmacist-managed CVRR federally qualified health clinics (FQHC) in Indiana, United States. Data were collected from patients seen by a CVRR pharmacist within the timeframe of January 1, 2015 through February 28, 2020. Data collected include: demographic characteristics and clinical markers between baseline and follow-up. HbA1C from baseline after 3 to 5 months was assessed with pared t-tests analysis. Other clinical variables were assessed and additional analysis were performed at 6–8 months. Additional results are reported between 9 months and 36 months of follow up. Results The primary outcome evaluation included 445 patients. Over 36 months of evaluation, 3,803 encounters were described. Compared to baseline, HbA1C was reduced by 1.6% (95%CI -1.8, -1.4, pConclusions Our study augments the existing literature by demonstrating the health improvement of pharmacist-managed CVRR clinics. The great proportion of loss to follow-up is a limitation of this study to be considered. Additional studies exploring the expansion of similar models may amplify the public health impact of pharmacist-managed CVRR services in primary care sites