Digital news report: Australia 2015

This report gives a clear picture of how the Australian news consumer compares to eleven other countries surveyed in 2015: Denmark, Finland, France, Germany, Ireland, Italy, Japan, Spain, UK, USA and urban Brazil. The Digital News Report: Australia is part of a global survey by the Reuters Institute for the Study of Journalism at the University of Oxford. Further in-depth analysis of Australian digital news consumption has been conducted and published by the News & Media Research Centre at the University of Canberra

Ethnic Insularity among 1.5- and Second-Generation Korean-American Christians

Building on insights from Min (2010) comparisons between Korean Protestants and Indian Hindus, and my findings of elite freshmen Korean racial insularity (Park 2012), I use data from the Immigration and Intergenerational Mobility in Metropolitan Los Angeles (2004) survey to examine the extent to which religion serves to not only preserve ethnicity but also support insularity in young adult 1.5- and second-generation (second generation hereafter) Korean Americans. Findings suggest that at the racial level of comparison, second-generation Korean-American endogamy resembles that of white, black, and Latino endogamy; second-generation Korean-American endogamy reflects not only the highest intraracial marriage rate, but also the highest intraethnic marriage rate of all Asian groups in the sample. Further, religious married second-generation Korean Americans have the highest racially homogeneous composition rate in the congregations they attend relative to other racial groups and other Asian ethnicities. In multivariate analyses, these two dynamics of marital endogamy and congregational racial homophily produce strong effects on one another and diminish the unique Korean effect. Findings suggest that these group relational patterns are more evident for second-generation Korean Americans and may have implications for social mobility in a racialized context

Angular Differential Cross Sections for 25-, 50-, and 100-kev-proton Excitation of Helium to the n=2 Level

Differential cross sections for 25-, 50-, and 100-keV-proton excitation of helium to the n=2 level have been determined for center-of-mass scattering angles from 0 to 1.2 mrad. The cross sections were obtained from an analysis of the angular distribution of the scattered protons which had lost an energy corresponding to the excitation of the helium target to its n=2 level. The differential cross section is very sharply peaked in the forward direction and decreases by a factor of 45 in 1.0 mrad at 25 keV and by a factor of 650 in 1.0 mrad at 100 keV. The data are in excellent agreement with a recent multistate eikonal calculation

Angular Differential Cross Sections for Excitation of Atomic Hydrogen to the n=2 Level by Proton Impact

Differential cross sections for 15-145-keV proton impact excitation of atomic hydrogen to the n=2 level have been determined for center-of-mass scattering angles 0 to 1.2 mrad. The cross sections were obtained from an analysis of the angular distribution of protons which had lost an energy corresponding to the excitation of atomic hydrogen to its n=2 level. The differential cross sections obtained are in rather good agreement with available coupled-state calculations as well as the simpler Glauber-approximation calculations. However, at the larger scattering angles the cross sections obtained from the theoretical treatments appear to decrease more rapidly than the experimental data

ATSC 3.0 Next Generation Digital TV Standard - An Overview and Preview of the Issue

"(c) 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works."The Advanced Television Committee (ATSC) has been working on the next generation broadcast television system, known as ATSC 3.0, to replace the first-generation (ATSC 1.0) A/53 standard, the basic component technologies of which have been in use for 20 years.Chernock, R.; Gómez Barquero, D.; Whitaker, J.; Park, S.; Wu, Y. (2016). ATSC 3.0 Next Generation Digital TV Standard - An Overview and Preview of the Issue. IEEE Transactions on Broadcasting. 62(1):154-158. doi:10.1109/TBC.2016.2515542S15415862

New Perspectives from International Visitors to Thailand

publishedVersio

eIF4A inhibitors suppress cell-cycle feedback response and acquired resistance to CDK4/6 inhibition in cancer

CDK4/6 inhibitors are FDA-approved drugs for estrogen receptor-positive (ER+) breast cancer and are being evaluated to treat other tumor types, including KRAS-mutant non-small cell lung cancer (NSCLC). However, their clinical utility is often limited by drug resistance. Here, we sought to better understand the resistant mechanisms and help devise potential strategies to overcome this challenge. We show that treatment with CDK4/6 inhibitors in both ER+ breast cancer and KRAS-mutant NSCLC cells induces feedback upregulation of cyclin D1, CDK4, and cyclin E1, mediating drug resistance. We demonstrate that rocaglates, which preferentially target translation of key cell-cycle regulators, effectively suppress this feedback upregulation induced by CDK4/6 inhibition. Consequently, combination treatment of CDK4/6 inhibitor palbociclib with the eukaryotic initiation factor (eIF) 4A inhibitor, CR-1-31-B, is synergistic in suppressing the growth of these cancer cells in vitro and in vivo Furthermore, ER+ breast cancer and KRAS-mutant NSCLC cells that acquired resistance to palbociclib after chronic drug exposure are also highly sensitive to this combination treatment strategy. Our findings reveal a novel strategy using eIF4A inhibitors to suppress cell-cycle feedback response and to overcome resistance to CDK4/6 inhibition in cancer.Accepted manuscrip